This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple ... See more...

Aliases for FARP1 Gene

Aliases for FARP1 Gene

  • FERM, ARH/RhoGEF And Pleckstrin Domain Protein 1 2 3 5
  • PLEKHC2 2 3 4
  • CDEP 2 3 4
  • FERM, RhoGEF (ARHGEF) And Pleckstrin Domain Protein 1 (Chondrocyte-Derived) 2 3
  • FERM, ARHGEF And Pleckstrin Domain-Containing Protein 1 3 4
  • FERM, RhoGEF And Pleckstrin Domain-Containing Protein 1 3 4
  • Pleckstrin Homology Domain-Containing Family C Member 2 3 4
  • Protein Phosphatase 1, Regulatory Subunit 75 2 3
  • PH Domain-Containing Family C Member 2 3 4
  • Chondrocyte-Derived Ezrin-Like Protein 3 4
  • PPP1R75 2 3
  • FARP1-IT1 3
  • MGC87400 2
  • FARP1 5

External Ids for FARP1 Gene

Previous GeneCards Identifiers for FARP1 Gene

  • GC13P097155
  • GC13P093182
  • GC13P097632
  • GC13P096493
  • GC13P097593
  • GC13P098795
  • GC13P079393

Summaries for FARP1 Gene

Entrez Gene Summary for FARP1 Gene

  • This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

GeneCards Summary for FARP1 Gene

FARP1 (FERM, ARH/RhoGEF And Pleckstrin Domain Protein 1) is a Protein Coding gene. Diseases associated with FARP1 include Nystagmus 3, Congenital, Autosomal Dominant and Nystagmus 7, Congenital, Autosomal Dominant. Among its related pathways are Regulation of RhoA activity. Gene Ontology (GO) annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and Rac GTPase binding. An important paralog of this gene is FARP2.

UniProtKB/Swiss-Prot Summary for FARP1 Gene

  • Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).

Gene Wiki entry for FARP1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FARP1 Gene

Genomics for FARP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FARP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J098141 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 +2.3 2270 5.8 KLF9 CEBPA POLR2A ZIC2 YY1 MXD4 ZNF639 ZNF341 CTCF SIN3A FARP1 LOC105370328 lnc-IPO5-3 lnc-RNF113B-1 RNF113B STK24-AS1 piR-49957
GH13J098143 Enhancer 0.4 CraniofacialAtlas 250.7 -0.7 -715 0.2 KLF9 SIN3A RXRA FARP1 lnc-IPO5-3 LOC105370328 lnc-RNF113B-1 HSALNG0098840 IPO5
GH13J098142 Enhancer 0.2 Ensembl 250.7 -1.3 -1261 0.2 FARP1 lnc-IPO5-3 LOC105370328 lnc-RNF113B-1 HSALNG0098840 IPO5
GH13J098205 Enhancer 0.8 Ensembl ENCODE dbSUPER 19 +65.0 65033 3.8 ZNF585B RBM22 RAD21 JUND YY1 EP300 FOS MIR3170 FARP1 STK24-AS1 HSALNG0098843 RN7SKP8 lnc-RNF113B-4 RNF113B RF00017-1337 lnc-IPO5-3 STK24
GH13J098219 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.5 +79.2 79152 4.5 NCOR1 ZNF580 FEZF1 ZNF341 TAL1 EBF1 PRDM6 TCF7L2 HDAC2 SCRT1 FARP1 MIR3170 ENSG00000269189 RF00017-1337 RNF113B STK24
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FARP1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FARP1

Top Transcription factor binding sites by QIAGEN in the FARP1 gene promoter:
  • AML1a
  • AP-1
  • c-Fos
  • c-Jun
  • CREB
  • deltaCREB
  • Elk-1
  • Msx-1
  • NRF-2
  • Pax-4a

Genomic Locations for FARP1 Gene

Latest Assembly
chr13:98,142,562-98,455,176
(GRCh38/hg38)
Size:
312,615 bases
Orientation:
Plus strand

Previous Assembly
chr13:98,794,843-99,107,430
(GRCh37/hg19 by Entrez Gene)
Size:
312,588 bases
Orientation:
Plus strand

chr13:98,794,816-99,102,027
(GRCh37/hg19 by Ensembl)
Size:
307,212 bases
Orientation:
Plus strand

Genomic View for FARP1 Gene

Genes around FARP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FARP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FARP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FARP1 Gene

Proteins for FARP1 Gene

  • Protein details for FARP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y4F1-FARP1_HUMAN
    Recommended name:
    FERM, ARHGEF and pleckstrin domain-containing protein 1
    Protein Accession:
    Q9Y4F1
    Secondary Accessions:
    • Q5JVI9
    • Q6IQ29

    Protein attributes for FARP1 Gene

    Size:
    1045 amino acids
    Molecular mass:
    118633 Da
    Quaternary structure:
    • Interacts with CADM1. Interacts with RAC1 (By similarity).

    Three dimensional structures from OCA and Proteopedia for FARP1 Gene

    Alternative splice isoforms for FARP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FARP1 Gene

Post-translational modifications for FARP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FARP1 Gene

Domains & Families for FARP1 Gene

Suggested Antigen Peptide Sequences for FARP1 Gene

GenScript: Design optimal peptide antigens:
  • Pleckstrin homology domain-containing family C member 2 (FARP1_HUMAN)
  • FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) (Q5JV91_HUMAN)
  • FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) (Q5JV94_HUMAN)
  • FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) (Q5JVI9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9Y4F1

UniProtKB/Swiss-Prot:

FARP1_HUMAN :
  • Intramolecular interaction between the DH domain and the PH domains can stabilize the protein in an autoinhibited conformation.
Domain:
  • Intramolecular interaction between the DH domain and the PH domains can stabilize the protein in an autoinhibited conformation.
genes like me logo Genes that share domains with FARP1: view

Function for FARP1 Gene

Molecular function for FARP1 Gene

UniProtKB/Swiss-Prot Function:
Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).
UniProtKB/Swiss-Prot Induction:
Up-regulated in response to cAMP in cultured embryonic chondrocytes.

Phenotypes From GWAS Catalog for FARP1 Gene

Gene Ontology (GO) - Molecular Function for FARP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005085 guanyl-nucleotide exchange factor activity IEA,ISS --
GO:0005515 protein binding IPI 32296183
GO:0008092 cytoskeletal protein binding IEA --
GO:0031267 small GTPase binding IEA --
genes like me logo Genes that share ontologies with FARP1: view
genes like me logo Genes that share phenotypes with FARP1: view

Animal Models for FARP1 Gene

MGI Knock Outs for FARP1:
  • Farp1 Farp1<tm1b(EUCOMM)Hmgu>

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FARP1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FARP1 Gene

Localization for FARP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FARP1 Gene

Cell membrane. Peripheral membrane protein. Cytoplasmic side. Cell junction, synapse. Cell junction, synapse, synaptosome. Cytoplasm, cytosol. Cell projection, filopodium. Cell projection, dendrite. Cell projection, dendritic spine. Note=Recruited to the cell membrane via interaction with CADM1. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FARP1 gene
Compartment Confidence
cytosol 5
plasma membrane 4
cytoskeleton 4
nucleus 3
extracellular 1
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for FARP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IEA,ISS --
GO:0005856 cytoskeleton IEA --
GO:0005886 plasma membrane IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with FARP1: view

Pathways & Interactions for FARP1 Gene

PathCards logo

SuperPathways for FARP1 Gene

SuperPathway Contained pathways
1 Regulation of RhoA activity
genes like me logo Genes that share pathways with FARP1: view

Pathways by source for FARP1 Gene

1 BioSystems pathway for FARP1 Gene

Gene Ontology (GO) - Biological Process for FARP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organism development IEA --
GO:0007416 synapse assembly IEA,ISS --
GO:0010923 negative regulation of phosphatase activity IDA 19389623
GO:0048813 dendrite morphogenesis IEA,ISS --
GO:0050790 regulation of catalytic activity IEA --
genes like me logo Genes that share ontologies with FARP1: view

No data available for SIGNOR curated interactions for FARP1 Gene

Drugs & Compounds for FARP1 Gene

(1) Drugs for FARP1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
cyclic amp Experimental Pharma 0
genes like me logo Genes that share compounds with FARP1: view

Transcripts for FARP1 Gene

mRNA/cDNA for FARP1 Gene

3 REFSEQ mRNAs :
18 NCBI additional mRNA sequence :
42 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FARP1

Alternative Splicing Database (ASD) splice patterns (SP) for FARP1 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22a ·
SP1: - - - - - - -
SP2: - - - - -
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:

ExUns: 22b ^ 23a · 23b ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32a · 32b ^ 33 ^ 34
SP1: -
SP2: - -
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:

Relevant External Links for FARP1 Gene

GeneLoc Exon Structure for
FARP1

Expression for FARP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FARP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for FARP1 Gene

This gene is overexpressed in Frontal cortex (8.6), Brain (8.6), and Fetal ovary (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FARP1 Gene



Protein tissue co-expression partners for FARP1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FARP1

SOURCE GeneReport for Unigene cluster for FARP1 Gene:

Hs.403917

mRNA Expression by UniProt/SwissProt for FARP1 Gene:

Q9Y4F1-FARP1_HUMAN
Tissue specificity: Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung.

Evidence on tissue expression from TISSUES for FARP1 Gene

  • Nervous system(4.9)
  • Skin(4.6)
  • Liver(4.2)
  • Eye(2.6)
  • Lung(2.4)
  • Kidney(2.2)
genes like me logo Genes that share expression patterns with FARP1: view

Primer products for research

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for FARP1 Gene

Orthologs for FARP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FARP1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia FARP1 29 30
  • 99.49 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia FARP1 29 30
  • 90.4 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia FARP1 30
  • 89 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia FARP1 29 30
  • 88.7 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia FARP1 30
  • 87 (a)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Farp1 29
  • 86.51 (n)
Mouse
(Mus musculus)
Mammalia Farp1 29 16 30
  • 86.32 (n)
OneToOne
Chicken
(Gallus gallus)
Aves FARP1 29 30
  • 78.99 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia FARP1 30
  • 85 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia farp1 29
  • 72.76 (n)
Zebrafish
(Danio rerio)
Actinopterygii farp1 30
  • 71 (a)
OneToOne
LOC100329707 29
  • 69.86 (n)
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10646 29
Fruit Fly
(Drosophila melanogaster)
Insecta Cdep 30
  • 35 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea frm-3 31
  • 33 (a)
F52D10.6 31
  • 29 (a)
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.8849 30
  • 44 (a)
OneToMany
Species where no ortholog for FARP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for FARP1 Gene

ENSEMBL:
Gene Tree for FARP1 (if available)
TreeFam:
Gene Tree for FARP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FARP1: view image
Alliance of Genome Resources:
Additional Orthologs for FARP1

Paralogs for FARP1 Gene

Paralogs for FARP1 Gene

(18) SIMAP similar genes for FARP1 Gene using alignment to 6 proteins:

  • FARP1_HUMAN
  • C9JME2_HUMAN
  • H0Y783_HUMAN
  • M0QXT1_HUMAN
  • M0QYB0_HUMAN
  • M0R262_HUMAN
genes like me logo Genes that share paralogs with FARP1: view

Variants for FARP1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FARP1 Gene

SNP ID Clinical significance and condition Chr 13 pos Variation AA Info Type
rs145802885 A breast cancer sample p.Arg714Leu
rs61730893 Benign: not provided 98,439,187(+) T/C
NM_005766.4(FARP1):c.2424T>C (p.Tyr808=)
SYNONYMOUS
rs9584848 Benign: not provided 98,440,189(+) C/T
NM_005766.4(FARP1):c.2583C>T (p.Ser861=)
SYNONYMOUS
rs9300466 -- p.Pro8Leu

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for FARP1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for FARP1 Gene

Variant ID Type Subtype PubMed ID
dgv3340n54 CNV gain 21841781
dgv3341n54 CNV loss 21841781
dgv3342n54 CNV gain 21841781
dgv3343n54 CNV loss 21841781
dgv3344n54 CNV gain 21841781
dgv3345n54 CNV loss 21841781
esv1283656 CNV insertion 17803354
esv2568558 CNV insertion 19546169
esv2642055 CNV insertion 19546169
esv2657451 CNV deletion 23128226
esv27463 CNV loss 19812545
esv2751157 CNV loss 17911159
esv2759959 CNV loss 17122850
esv3305227 CNV mobile element insertion 20981092
esv3310565 CNV novel sequence insertion 20981092
esv3334889 CNV duplication 20981092
esv3366644 CNV insertion 20981092
esv3382243 CNV insertion 20981092
esv3414683 CNV insertion 20981092
esv34957 CNV loss 17911159
esv3580856 CNV loss 25503493
esv3633305 CNV loss 21293372
esv3633306 CNV loss 21293372
esv3633309 CNV loss 21293372
esv3633310 CNV loss 21293372
esv988052 CNV insertion 20482838
nsv1039403 CNV loss 25217958
nsv1045047 CNV gain 25217958
nsv1118269 CNV deletion 24896259
nsv1121865 CNV deletion 24896259
nsv1134344 CNV deletion 24896259
nsv1138254 CNV deletion 24896259
nsv1142837 CNV tandem duplication 24896259
nsv1144697 CNV deletion 24896259
nsv456087 CNV loss 19166990
nsv456088 CNV gain 19166990
nsv471172 CNV gain 18288195
nsv473246 CNV novel sequence insertion 20440878
nsv476994 CNV novel sequence insertion 20440878
nsv509511 CNV insertion 20534489
nsv510359 OTHER sequence alteration 20534489
nsv517409 CNV gain+loss 19592680
nsv528803 CNV loss 19592680
nsv562855 CNV gain 21841781
nsv562860 CNV gain 21841781
nsv562863 CNV loss 21841781
nsv562866 CNV loss 21841781
nsv562867 CNV loss 21841781
nsv562868 CNV gain 21841781
nsv562871 CNV loss 21841781
nsv562872 CNV loss 21841781
nsv7246 OTHER inversion 18451855
nsv818991 CNV loss 17921354
nsv832695 CNV loss 17160897

Variation tolerance for FARP1 Gene

Residual Variation Intolerance Score: 33.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.63; 72.65% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FARP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FARP1
Leiden Open Variation Database (LOVD)
FARP1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FARP1 Gene

Disorders for FARP1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for FARP1 Gene - From: COP

- elite association - COSMIC cancer census association via MalaCards
Search FARP1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for FARP1

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with FARP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FARP1 Gene

Publications for FARP1 Gene

  1. Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors. (PMID: 9425278) Koyano Y … Kato Y (Biochemical and biophysical research communications 1997) 2 3 4 22
  2. Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2. (PMID: 23375260) He X … Zhang X (Structure (London, England : 1993) 2013) 3 4
  3. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PMID: 21116278) Furney SJ … AddNeuroMed Consortium (Molecular psychiatry 2011) 3 40
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 40
  5. Voxelwise genome-wide association study (vGWAS). (PMID: 20171287) Stein JL … Alzheimer's Disease Neuroimaging Initiative (NeuroImage 2010) 3 40

Products for FARP1 Gene

Sources for FARP1 Gene