Aliases for FAM83D Gene
External Ids for FAM83D Gene
Previous HGNC Symbols for FAM83D Gene
Previous GeneCards Identifiers for FAM83D Gene
GeneCards Summary for FAM83D Gene
FAM83D (Family With Sequence Similarity 83 Member D) is a Protein Coding gene. An important paralog of this gene is FAM83G.
UniProtKB/Swiss-Prot Summary for FAM83D Gene
Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.