Aliases for FAM83A Gene
External Ids for FAM83A Gene
Previous GeneCards Identifiers for FAM83A Gene
GeneCards Summary for FAM83A Gene
FAM83A (Family With Sequence Similarity 83 Member A) is a Protein Coding gene. Diseases associated with FAM83A include Amelogenesis Imperfecta, Type Iiia and Trichorhinophalangeal Syndrome, Type Ii. An important paralog of this gene is FAM83C.
UniProtKB/Swiss-Prot Summary for FAM83A Gene
Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation.