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Aliases for FAM72C Gene

Aliases for FAM72C Gene

  • Family With Sequence Similarity 72 Member C 2 3 5
  • Family With Sequence Similarity 72, Member C 2
  • Protein FAM72C 3
  • RP5-998N21.9 3

External Ids for FAM72C Gene

Previous GeneCards Identifiers for FAM72C Gene

  • GC01U901175
  • GC01M149438
  • GC01M143944

Summaries for FAM72C Gene

GeneCards Summary for FAM72C Gene

FAM72C (Family With Sequence Similarity 72 Member C) is a Protein Coding gene. An important paralog of this gene is FAM72D.

Additional gene information for FAM72C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM72C Gene

Genomics for FAM72C Gene

GeneHancer (GH) Regulatory Elements for FAM72C Gene

Promoters and enhancers for FAM72C Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I143971 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 550.8 +1.1 1104 4.2 HDGF PKNOX1 ATF1 SIN3A GLIS2 ZNF143 ATF7 FOS SP3 NFYC FAM72C SRGAP2D
GH01I143988 Enhancer 0.8 Ensembl 0.4 -15.3 -15296 1.8 PKNOX1 INSM2 KLF17 FEZF1 ZNF2 ZEB1 ZNF366 ZSCAN5C ZNF680 CEBPB FAM72C SRGAP2D GC01P144021
GH01I144009 Enhancer 0.6 Ensembl ENCODE 0.3 -35.7 -35695 1 PKNOX1 IKZF1 ATF7 GC01P144021 SRGAP2D FAM72C
GH01I143966 Enhancer 0.4 ENCODE 0.4 +7.9 7876 0.1 PRDM6 SP7 FAM72C SRGAP2D GC01M143949
GH01I144014 Enhancer 0.5 Ensembl 0.3 -41.1 -41095 2.6 MEIS2 LEF1 FOXK2 NR2C1 ZNF592 GC01P144021 SRGAP2D FAM72C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM72C on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM72C Gene

Genomic Locations for FAM72C Gene
18,842 bases
Minus strand

Genomic View for FAM72C Gene

Genes around FAM72C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM72C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM72C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM72C Gene

Proteins for FAM72C Gene

  • Protein details for FAM72C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM72C
    Protein Accession:

    Protein attributes for FAM72C Gene

    149 amino acids
    Molecular mass:
    16730 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM72C Gene

Post-translational modifications for FAM72C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM72C Gene

Domains & Families for FAM72C Gene

Gene Families for FAM72C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM72C Gene


Suggested Antigen Peptide Sequences for FAM72C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM72 family.
  • Belongs to the FAM72 family.
genes like me logo Genes that share domains with FAM72C: view

Function for FAM72C Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM72C Gene

Localization for FAM72C Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM72C gene
Compartment Confidence
extracellular 3
plasma membrane 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Plasma membrane (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for FAM72C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IDA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with FAM72C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM72C Gene

Pathways & Interactions for FAM72C Gene

SuperPathways for FAM72C Gene

No Data Available

Interacting Proteins for FAM72C Gene

Gene Ontology (GO) - Biological Process for FAM72C Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM72C Gene

Drugs & Compounds for FAM72C Gene

No Compound Related Data Available

Transcripts for FAM72C Gene

mRNA/cDNA for FAM72C Gene

(8) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM72C Gene

Family with sequence similarity 72, member C:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM72C Gene

No ASD Table

Relevant External Links for FAM72C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM72C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM72C Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM72C Gene:


SOURCE GeneReport for Unigene cluster for FAM72C Gene:

genes like me logo Genes that share expression patterns with FAM72C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM72C Gene

Orthologs for FAM72C Gene

Evolution for FAM72C Gene

Gene Tree for FAM72C (if available)
Gene Tree for FAM72C (if available)

No data available for Orthologs for FAM72C Gene

Paralogs for FAM72C Gene

Paralogs for FAM72C Gene

(3) SIMAP similar genes for FAM72C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM72C: view

Variants for FAM72C Gene

Sequence variations from dbSNP and Humsavar for FAM72C Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs10718 -- 143,955,516(-) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1260177 -- 143,955,304(-) C/T downstream_transcript_variant
rs1321214 -- 143,955,031(-) G/A/C downstream_transcript_variant
rs1338870 -- 143,955,645(-) T/C 3_prime_UTR_variant, genic_downstream_transcript_variant
rs139024480 -- 143,958,249(-) G/A genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM72C Gene

Variant ID Type Subtype PubMed ID
dgv380n100 CNV gain+loss 25217958
dgv381n100 CNV gain 25217958
dgv383n100 CNV loss 25217958
dgv397n100 CNV loss 25217958
esv21838 CNV gain+loss 19812545
esv26241 CNV gain+loss 19812545
esv3894067 CNV gain 25118596
esv3894156 CNV loss 25118596
esv3894189 CNV gain+loss 25118596
nsv1128610 CNV duplication 24896259
nsv1139490 CNV duplication 24896259
nsv1148298 CNV duplication 26484159
nsv831237 CNV gain 17160897
nsv946195 CNV duplication 23825009
nsv946220 CNV duplication 23825009
nsv946367 CNV duplication 23825009

Additional Variant Information for FAM72C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM72C Gene

Disorders for FAM72C Gene

Additional Disease Information for FAM72C

No disorders were found for FAM72C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM72C Gene

Publications for FAM72C Gene

  1. All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci. (PMID: 26206078) Kutzner A … Heese K (Genomics 2015) 2 3 58
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58

Products for FAM72C Gene

Sources for FAM72C Gene

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