Aliases for FAM47B Gene

Aliases for FAM47B Gene

  • Family With Sequence Similarity 47 Member B 2 3 5
  • Protein FAM47B 3 4
  • Family With Sequence Similarity 47, Member B 2

External Ids for FAM47B Gene

Previous GeneCards Identifiers for FAM47B Gene

  • GC0XP034720
  • GC0XP032702

Summaries for FAM47B Gene

GeneCards Summary for FAM47B Gene

FAM47B (Family With Sequence Similarity 47 Member B) is a Protein Coding gene. An important paralog of this gene is FAM47C.

Additional gene information for FAM47B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM47B Gene

Genomics for FAM47B Gene

GeneHancer (GH) Regulatory Elements for FAM47B Gene

Promoters and enhancers for FAM47B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ034915 Enhancer 0.4 Ensembl 0.3 -26.9 -26895 0.2 FOS JUND HNF4A ATF3 SP1 piR-39858-682 FAM47B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM47B on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FAM47B

Top Transcription factor binding sites by QIAGEN in the FAM47B gene promoter:
  • Evi-1
  • GCNF
  • GCNF-1
  • GCNF-2
  • Pax-6

Genomic Locations for FAM47B Gene

Genomic Locations for FAM47B Gene
2,122 bases
Plus strand
2,122 bases
Plus strand

Genomic View for FAM47B Gene

Genes around FAM47B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM47B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM47B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM47B Gene

Proteins for FAM47B Gene

  • Protein details for FAM47B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM47B
    Protein Accession:
    Secondary Accessions:
    • Q5JQN5
    • Q6PIG3

    Protein attributes for FAM47B Gene

    645 amino acids
    Molecular mass:
    73945 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM47B Gene

Post-translational modifications for FAM47B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM47B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM47B Gene

Domains & Families for FAM47B Gene

Gene Families for FAM47B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM47B Gene


Suggested Antigen Peptide Sequences for FAM47B Gene

GenScript: Design optimal peptide antigens:
  • Protein FAM47B (FA47B_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM47 family.
  • Belongs to the FAM47 family.
genes like me logo Genes that share domains with FAM47B: view

Function for FAM47B Gene

Phenotypes From GWAS Catalog for FAM47B Gene

genes like me logo Genes that share phenotypes with FAM47B: view

miRNA for FAM47B Gene

miRTarBase miRNAs that target FAM47B

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM47B Gene

Localization for FAM47B Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM47B gene
Compartment Confidence
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM47B Gene

Pathways & Interactions for FAM47B Gene

PathCards logo

SuperPathways for FAM47B Gene

No Data Available

Interacting Proteins for FAM47B Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000328307 Q8NA70-FA47B_HUMAN for FAM47B Gene via STRING IID


Gene Ontology (GO) - Biological Process for FAM47B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM47B Gene

Drugs & Compounds for FAM47B Gene

No Compound Related Data Available

Transcripts for FAM47B Gene

mRNA/cDNA for FAM47B Gene

4 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM47B Gene

No ASD Table

Relevant External Links for FAM47B Gene

GeneLoc Exon Structure for

Expression for FAM47B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM47B Gene

mRNA differential expression in normal tissues according to GTEx for FAM47B Gene

This gene is overexpressed in Testis (x52.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FAM47B

SOURCE GeneReport for Unigene cluster for FAM47B Gene:

genes like me logo Genes that share expression patterns with FAM47B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM47B Gene

Orthologs for FAM47B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM47B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM47B 31
  • 95 (a)
LOC473866 30
  • 84.92 (n)
(Canis familiaris)
Mammalia -- 31
  • 45 (a)
(Mus musculus)
Mammalia Fam47c 31
  • 37 (a)
4930480E11Rik 31
  • 25 (a)
4930402K13Rik 31
  • 21 (a)
(Monodelphis domestica)
Mammalia -- 31
  • 27 (a)
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 26 (a)
(Anolis carolinensis)
Reptilia -- 31
  • 24 (a)
-- 31
  • 21 (a)
(Danio rerio)
Actinopterygii zgc:158260 31 31
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4199 31
  • 20 (a)
Species where no ortholog for FAM47B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM47B Gene

Gene Tree for FAM47B (if available)
Gene Tree for FAM47B (if available)
Evolutionary constrained regions (ECRs) for FAM47B: view image

Paralogs for FAM47B Gene

(1) SIMAP similar genes for FAM47B Gene using alignment to 1 proteins:

  • FA47B_HUMAN Pseudogenes for FAM47B Gene

genes like me logo Genes that share paralogs with FAM47B: view

Variants for FAM47B Gene

Additional dbSNP identifiers (rs#s) for FAM47B Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM47B Gene

Variant ID Type Subtype PubMed ID
esv2664433 CNV deletion 23128226
esv3573850 CNV loss 25503493
nsv519107 CNV gain 19592680
nsv527976 CNV gain 19592680

Variation tolerance for FAM47B Gene

Residual Variation Intolerance Score: 96% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.27; 40.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM47B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM47B Gene

Disorders for FAM47B Gene

Additional Disease Information for FAM47B

No disorders were found for FAM47B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM47B Gene

Publications for FAM47B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4 54
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 54
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  4. Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. (PMID: 24510904) Beilina A … Cookson MR (Proceedings of the National Academy of Sciences of the United States of America 2014) 3 54
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 54

Products for FAM47B Gene

Sources for FAM47B Gene