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Aliases for FAM27E3 Gene

Subcategory (RNA class) for FAM27E3 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for FAM27E3 Gene

  • Family With Sequence Similarity 27 Member E3 2 3 5
  • Family With Sequence Similarity 27, Member E3 2

External Ids for FAM27E3 Gene

Previous GeneCards Identifiers for FAM27E3 Gene

  • GC09U900765
  • GC09M067375
  • GC09M046277

Summaries for FAM27E3 Gene

GeneCards Summary for FAM27E3 Gene

FAM27E3 (Family With Sequence Similarity 27 Member E3) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for FAM27E3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM27E3 Gene

Genomics for FAM27E3 Gene

GeneHancer (GH) Regulatory Elements for FAM27E3 Gene

Promoters and enhancers for FAM27E3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I067717 Enhancer 0.2 Ensembl 550.8 +1.2 1160 1.2 FAM27E3 ENSG00000278735 ENSG00000275614
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM27E3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the FAM27E3 gene promoter:

Genomic Locations for FAM27E3 Gene

Genomic Locations for FAM27E3 Gene
1,769 bases
Minus strand

Genomic View for FAM27E3 Gene

Genes around FAM27E3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM27E3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM27E3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM27E3 Gene

Proteins for FAM27E3 Gene

  • Protein details for FAM27E3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM27E3
    Protein Accession:

    Protein attributes for FAM27E3 Gene

    113 amino acids
    Molecular mass:
    13507 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM27E3 Gene

Post-translational modifications for FAM27E3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM27E3 Gene

Domains & Families for FAM27E3 Gene

Protein Domains for FAM27E3 Gene


Suggested Antigen Peptide Sequences for FAM27E3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM27 family.
  • Belongs to the FAM27 family.
genes like me logo Genes that share domains with FAM27E3: view

No data available for Gene Families for FAM27E3 Gene

Function for FAM27E3 Gene

Gene Ontology (GO) - Molecular Function for FAM27E3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM27E3: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM27E3 Gene

Localization for FAM27E3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM27E3 Gene

Pathways & Interactions for FAM27E3 Gene

SuperPathways for FAM27E3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM27E3 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM27E3 Gene

Drugs & Compounds for FAM27E3 Gene

No Compound Related Data Available

Transcripts for FAM27E3 Gene

mRNA/cDNA for FAM27E3 Gene

(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM27E3 Gene

Family with sequence similarity 27, member E3:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM27E3 Gene

No ASD Table

Relevant External Links for FAM27E3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM27E3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM27E3 Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM27E3 Gene:


SOURCE GeneReport for Unigene cluster for FAM27E3 Gene:

genes like me logo Genes that share expression patterns with FAM27E3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM27E3 Gene

Orthologs for FAM27E3 Gene

Evolution for FAM27E3 Gene

Gene Tree for FAM27E3 (if available)
Gene Tree for FAM27E3 (if available)

No data available for Orthologs for FAM27E3 Gene

Paralogs for FAM27E3 Gene

(3) SIMAP similar genes for FAM27E3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM27E3: view

No data available for Paralogs for FAM27E3 Gene

Variants for FAM27E3 Gene

Sequence variations from dbSNP and Humsavar for FAM27E3 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000995894 -- 67,718,183(-) C/G non_coding_transcript_variant
rs1001278026 -- 67,718,767(-) T/A non_coding_transcript_variant
rs1002665183 -- 67,720,353(-) G/A/C upstream_transcript_variant
rs1002782024 -- 67,718,909(-) T/C non_coding_transcript_variant
rs1004428894 -- 67,718,549(-) T/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM27E3 Gene

Variant ID Type Subtype PubMed ID
dgv1348e199 CNV deletion 23128226
esv2672729 CNV deletion 23128226
esv28583 CNV gain+loss 19812545
esv996891 CNV gain 20482838
nsv1077126 CNV deletion 25765185
nsv8471 CNV gain 18304495
nsv951169 CNV deletion 24416366
nsv968661 CNV duplication 23825009

Variation tolerance for FAM27E3 Gene

Gene Damage Index Score: 0.08; 1.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM27E3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM27E3 Gene

Disorders for FAM27E3 Gene

Additional Disease Information for FAM27E3

No disorders were found for FAM27E3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM27E3 Gene

Publications for FAM27E3 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. (PMID: 27880917) St-Denis N … Gingras AC (Cell reports 2016) 3 58
  4. A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. (PMID: 25036637) Taipale M … Lindquist S (Cell 2014) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for FAM27E3 Gene

Sources for FAM27E3 Gene

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