Aliases for FAM25E Gene

Aliases for FAM25E Gene

  • Family With Sequence Similarity 25 Member E 2 3 5
  • Family With Sequence Similarity 25 Member D 2 3
  • Protein FAM25E 3 4
  • FAM25D 3 4
  • Family With Sequence Similarity 25, Member E 2
  • Family With Sequence Similarity 25, Member D 2
  • Protein FAM25D/E 3
  • AC012044.5 2
  • BA592B15.5 2
  • FAM25E 5

External Ids for FAM25E Gene

Previous HGNC Symbols for FAM25E Gene

  • FAM25D

Previous GeneCards Identifiers for FAM25E Gene

  • GC10U900497
  • GC10M050888
  • GC10M046310

Summaries for FAM25E Gene

GeneCards Summary for FAM25E Gene

FAM25E (Family With Sequence Similarity 25 Member E) is a Protein Coding gene.

Additional gene information for FAM25E Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM25E Gene

Genomics for FAM25E Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FAM25E Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J045726 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.2 +89.8 89823 3.4 SP1 CREB1 PRDM10 ZNF629 TFE3 LEF1 IKZF1 ZNF692 FOS TARDBP WASHC2C ENSG00000228702 FAM21FP LOC107984227 MN296977 lnc-ZFAND4-2 lnc-ZFAND4-3 PARGP1 AGAP4 ENSG00000229227
GH10J045802 Enhancer 0.4 Ensembl 0.4 +13.8 13823 2.2 RFX1 FOXA2 FOXA1 MNT ENSG00000270434 lnc-AGAP4-3 FAM25E MN309166-001 WASHC2C
GH10J045821 Enhancer 0.2 Ensembl 0.7 -4.4 -4377 4.6 MN309098-001 FAM25E piR-40318-002 AGAP4
GH10J045814 Enhancer 0.2 Ensembl 0.7 +2.8 2823 0.2 ENSG00000270434 lnc-AGAP4-3 FAM25E lnc-AGAP4-1 WASHC2C
GH10J045812 Enhancer 0.2 Ensembl 0.7 +4.4 4423 0.2 ENSG00000270434 lnc-AGAP4-3 FAM25E MN309166-001 WASHC2C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM25E on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FAM25E

Genomic Locations for FAM25E Gene

Genomic Locations for FAM25E Gene
chr10:45,815,428-45,817,324
(GRCh38/hg38)
Size:
1,897 bases
Orientation:
Minus strand
chr10:46,310,876-46,313,036
(GRCh37/hg19)
Size:
2,161 bases
Orientation:
Minus strand

Genomic View for FAM25E Gene

Genes around FAM25E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM25E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM25E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM25E Gene

Proteins for FAM25E Gene

  • Protein details for FAM25E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MYX2-FM25E_HUMAN
    Recommended name:
    Protein FAM25E
    Protein Accession:
    A8MYX2

    Protein attributes for FAM25E Gene

    Size:
    175 amino acids
    Molecular mass:
    18345 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM25E Gene

Post-translational modifications for FAM25E Gene

No Post-translational modifications

Other Protein References for FAM25E Gene

REFSEQ proteins:

No data available for DME Specific Peptides for FAM25E Gene

Domains & Families for FAM25E Gene

Protein Domains for FAM25E Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM25E Gene

GenScript: Design optimal peptide antigens:
  • Protein FAM25D/E (F25DE_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A8MYX2

UniProtKB/Swiss-Prot:

FM25E_HUMAN :
  • Belongs to the FAM25 family.
Family:
  • Belongs to the FAM25 family.
genes like me logo Genes that share domains with FAM25E: view

No data available for Gene Families for FAM25E Gene

Function for FAM25E Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM25E Gene

Localization for FAM25E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM25E Gene

Pathways & Interactions for FAM25E Gene

PathCards logo

SuperPathways for FAM25E Gene

No Data Available

Interacting Proteins for FAM25E Gene

Gene Ontology (GO) - Biological Process for FAM25E Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM25E Gene

Drugs & Compounds for FAM25E Gene

No Compound Related Data Available

Transcripts for FAM25E Gene

mRNA/cDNA for FAM25E Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM25E Gene

No ASD Table

Relevant External Links for FAM25E Gene

GeneLoc Exon Structure for
FAM25E

Expression for FAM25E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM25E Gene

Protein differential expression in normal tissues from HIPED for FAM25E Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM25E Gene



Protein tissue co-expression partners for FAM25E Gene

genes like me logo Genes that share expression patterns with FAM25E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM25E Gene

Orthologs for FAM25E Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM25E Gene

Organism Taxonomy Gene Similarity Type Details
Cow
(Bos Taurus)
Mammalia -- 31
  • 70 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Fam25c 31
  • 65 (a)
OneToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 58 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 53 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 49 (a)
OneToMany
Species where no ortholog for FAM25E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for FAM25E Gene

ENSEMBL:
Gene Tree for FAM25E (if available)
TreeFam:
Gene Tree for FAM25E (if available)

Paralogs for FAM25E Gene

(4) SIMAP similar genes for FAM25E Gene using alignment to 1 proteins:

  • F25DE_HUMAN
genes like me logo Genes that share paralogs with FAM25E: view

No data available for Paralogs for FAM25E Gene

Variants for FAM25E Gene

Additional dbSNP identifiers (rs#s) for FAM25E Gene

Additional Variant Information for FAM25E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM25E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for FAM25E Gene

Disorders for FAM25E Gene

Additional Disease Information for FAM25E

No disorders were found for FAM25E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM25E Gene

Publications for FAM25E Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4

Products for FAM25E Gene

Sources for FAM25E Gene