Aliases for FAM25C Gene

Aliases for FAM25C Gene

  • Family With Sequence Similarity 25 Member C 2 3 5
  • Protein FAM25C 3 4
  • BA164N7.4 2 3
  • Family With Sequence Similarity 25, Member C 2
  • Protein FAM25G 3
  • Protein FAM25 3
  • FAM25C 5

External Ids for FAM25C Gene

Previous GeneCards Identifiers for FAM25C Gene

  • GC10U900496
  • GC10P047870
  • GC10M046601
  • GC10P088777
  • GC10M048879
  • GC10M049199

Summaries for FAM25C Gene

GeneCards Summary for FAM25C Gene

FAM25C (Family With Sequence Similarity 25 Member C) is a Protein Coding gene. An important paralog of this gene is FAM25G.

Additional gene information for FAM25C Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM25C Gene

Genomics for FAM25C Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FAM25C Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J047999 Promoter/Enhancer 0.5 EPDnew Ensembl 600.7 0.0 -10 0.4 FAM25C MN309098-004 FRMPD2
GH10J048002 Enhancer 0.2 Ensembl 600.7 -1.9 -1910 2.6 FAM25C MN309098-004 FRMPD2
GH10J048102 Enhancer 0.2 Ensembl 4.3 -103.0 -103010 0.8 FAM25C lnc-NPY4R2-6 piR-37541-002 PTPN20CP FRMPD2
GH10J048010 Promoter 0.3 EPDnew 0.4 -10.7 -10697 0.1 piR-32403-007 piR-36657-007 piR-31838-005 piR-35327-004 piR-40318-007 piR-53110-006 piR-61533-007 AGAP9 FAM25C AGAP12P
GH10J048004 Enhancer 0.2 Ensembl 0.4 -5.1 -5110 0.2 MN309098-004 FAM25C FRMPD2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM25C on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FAM25C

Top Transcription factor binding sites by QIAGEN in the FAM25C gene promoter:
  • AML1a
  • CUTL1
  • FAC1
  • GATA-1
  • Ik-3
  • p300
  • YY1

Genomic Locations for FAM25C Gene

Genomic Locations for FAM25C Gene
4,470 bases
Minus strand
8,177 bases
Minus strand

Genomic View for FAM25C Gene

Genes around FAM25C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM25C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM25C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM25C Gene

Proteins for FAM25C Gene

  • Protein details for FAM25C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM25C
    Protein Accession:
    Secondary Accessions:
    • B2RV02
    • Q5VTM1

    Protein attributes for FAM25C Gene

    89 amino acids
    Molecular mass:
    9320 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM25C Gene

Post-translational modifications for FAM25C Gene

No Post-translational modifications

Other Protein References for FAM25C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM25C Gene

Domains & Families for FAM25C Gene

Gene Families for FAM25C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM25C Gene


Suggested Antigen Peptide Sequences for FAM25C Gene

GenScript: Design optimal peptide antigens:
  • Family with sequence similarity 25, member C (B7ZW47_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM25 family.
  • Belongs to the FAM25 family.
genes like me logo Genes that share domains with FAM25C: view

Function for FAM25C Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM25C

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM25C Gene

Localization for FAM25C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM25C Gene

Pathways & Interactions for FAM25C Gene

PathCards logo

SuperPathways for FAM25C Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM25C Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM25C Gene

Drugs & Compounds for FAM25C Gene

No Compound Related Data Available

Transcripts for FAM25C Gene

mRNA/cDNA for FAM25C Gene

10 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM25C

Alternative Splicing Database (ASD) splice patterns (SP) for FAM25C Gene

No ASD Table

Relevant External Links for FAM25C Gene

GeneLoc Exon Structure for

Expression for FAM25C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM25C Gene

mRNA differential expression in normal tissues according to GTEx for FAM25C Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x18.3), Skin - Not Sun Exposed (Suprapubic) (x15.7), and Esophagus - Mucosa (x6.8).

Protein differential expression in normal tissues from HIPED for FAM25C Gene

This gene is overexpressed in Saliva (68.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM25C Gene

Protein tissue co-expression partners for FAM25C Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FAM25C

SOURCE GeneReport for Unigene cluster for FAM25C Gene:

genes like me logo Genes that share expression patterns with FAM25C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM25C Gene

Orthologs for FAM25C Gene

Evolution for FAM25C Gene

Gene Tree for FAM25C (if available)
Gene Tree for FAM25C (if available)
Evolutionary constrained regions (ECRs) for FAM25C: view image

No data available for Orthologs for FAM25C Gene

Paralogs for FAM25C Gene

Paralogs for FAM25C Gene

(5) SIMAP similar genes for FAM25C Gene using alignment to 2 proteins:

  • B7ZW47_HUMAN
genes like me logo Genes that share paralogs with FAM25C: view

Variants for FAM25C Gene

Additional dbSNP identifiers (rs#s) for FAM25C Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM25C Gene

Variant ID Type Subtype PubMed ID
dgv12e203 CNV loss 21179565
esv24863 CNV gain+loss 19812545
esv33214 CNV loss 17666407
nsv1042677 CNV loss 25217958
nsv1118173 CNV deletion 24896259
nsv469669 CNV gain+loss 16826518
nsv820931 CNV deletion 20802225
nsv947974 CNV duplication 23825009
nsv982760 CNV duplication 23825009

Variation tolerance for FAM25C Gene

Gene Damage Index Score: 0.22; 4.94% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM25C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM25C Gene

Disorders for FAM25C Gene

No disorders were found for FAM25C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM25C Gene

Publications for FAM25C Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
  2. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for FAM25C Gene

Sources for FAM25C Gene