This locus represents naturally occurring read-through transcription between the neighboring FAM24B (family with sequence similarity 24, member B) and CUZD1 (CUB and zona pellucida-like domains 1) genes on chromosome 10. The read-transcript is a candidate for nonsense-mediated mRNA decay, and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011] See more...

Aliases for FAM24B-CUZD1 Gene

Subcategory (RNA class) for FAM24B-CUZD1 Gene

lncRNA

Number of RNA Genes sources:

1 / 14

Aliases for FAM24B-CUZD1 Gene

  • FAM24B-CUZD1 Readthrough 3
  • CUB And Zona Pellucida-Like Domain-Containing Protein 1 3
  • CUB And ZP Domain-Containing Protein 1 3
  • Transmembrane Protein UO-44 3
  • Lnc-FAM24B-1 168
  • CUZD1 3

External Ids for FAM24B-CUZD1 Gene

Previous GeneCards Identifiers for FAM24B-CUZD1 Gene

  • GC10U901494
  • GC10M124591

Summaries for FAM24B-CUZD1 Gene

Entrez Gene Summary for FAM24B-CUZD1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring FAM24B (family with sequence similarity 24, member B) and CUZD1 (CUB and zona pellucida-like domains 1) genes on chromosome 10. The read-transcript is a candidate for nonsense-mediated mRNA decay, and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for FAM24B-CUZD1 Gene

FAM24B-CUZD1 (FAM24B-CUZD1 Readthrough) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for FAM24B-CUZD1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM24B-CUZD1 Gene

Genomics for FAM24B-CUZD1 Gene

GeneHancer (GH) Regulatory Elements for FAM24B-CUZD1 Gene

Promoters and enhancers for FAM24B-CUZD1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM24B-CUZD1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM24B-CUZD1 Gene

Genomic Locations for FAM24B-CUZD1 Gene
chr10:122,832,155-122,879,641
(GRCh38/hg38)
Size:
47,487 bases
Orientation:
Minus strand
chr10:124,591,671-124,639,157
(GRCh37/hg19)
Size:
47,487 bases
Orientation:
Minus strand

Genomic View for FAM24B-CUZD1 Gene

Genes around FAM24B-CUZD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM24B-CUZD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM24B-CUZD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM24B-CUZD1 Gene

Proteins for FAM24B-CUZD1 Gene

Post-translational modifications for FAM24B-CUZD1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM24B-CUZD1 Gene

Domains & Families for FAM24B-CUZD1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FAM24B-CUZD1 Gene

Function for FAM24B-CUZD1 Gene

Phenotypes From GWAS Catalog for FAM24B-CUZD1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM24B-CUZD1 Gene

Localization for FAM24B-CUZD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM24B-CUZD1 Gene

Pathways & Interactions for FAM24B-CUZD1 Gene

PathCards logo

SuperPathways for FAM24B-CUZD1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for FAM24B-CUZD1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for FAM24B-CUZD1 Gene

Drugs & Compounds for FAM24B-CUZD1 Gene

No Compound Related Data Available

Transcripts for FAM24B-CUZD1 Gene

mRNA/cDNA for FAM24B-CUZD1 Gene

4 RNACentral transcripts :
1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
3 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM24B-CUZD1 Gene

No ASD Table

Relevant External Links for FAM24B-CUZD1 Gene

GeneLoc Exon Structure for
FAM24B-CUZD1

Expression for FAM24B-CUZD1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM24B-CUZD1 Gene

Orthologs for FAM24B-CUZD1 Gene

No data available for Orthologs and Evolution for FAM24B-CUZD1 Gene

Paralogs for FAM24B-CUZD1 Gene

No data available for Paralogs for FAM24B-CUZD1 Gene

Variants for FAM24B-CUZD1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM24B-CUZD1 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
rs11365591 Benign: not specified. Benign: not specified 122,836,358(-) GA/GGAA/G INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for FAM24B-CUZD1 Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM24B-CUZD1 Gene

Variant ID Type Subtype PubMed ID
esv3624789 CNV gain 21293372
esv7958 CNV gain 19470904
nsv1054197 CNV loss 25217958
nsv1159779 CNV deletion 26073780
nsv832010 CNV gain 17160897
nsv975804 CNV duplication 23825009

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Additional Variant Information for FAM24B-CUZD1 Gene

Disorders for FAM24B-CUZD1 Gene

No disorders were found for FAM24B-CUZD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for FAM24B-CUZD1 Gene

Publications for FAM24B-CUZD1 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 54
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 54

No data available for Mastermind for FAM24B-CUZD1 Gene

Products for FAM24B-CUZD1 Gene

Sources for FAM24B-CUZD1 Gene