Aliases for FAM24B Gene

Aliases for FAM24B Gene

  • Family With Sequence Similarity 24 Member B 2 3 5
  • Protein FAM24B 3 4
  • Family With Sequence Similarity 24, Member B 2

External Ids for FAM24B Gene

Previous GeneCards Identifiers for FAM24B Gene

  • GC10M124149
  • GC10M124581
  • GC10M124599
  • GC10M118226

Summaries for FAM24B Gene

GeneCards Summary for FAM24B Gene

FAM24B (Family With Sequence Similarity 24 Member B) is a Protein Coding gene. An important paralog of this gene is FAM24A.

Additional gene information for FAM24B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM24B Gene

Genomics for FAM24B Gene

GeneHancer (GH) Regulatory Elements for FAM24B Gene

Promoters and enhancers for FAM24B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM24B on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FAM24B

Top Transcription factor binding sites by QIAGEN in the FAM24B gene promoter:
  • HTF
  • NF-kappaB
  • NF-kappaB1
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v3
  • Nkx3-1 v4
  • POU2F1
  • POU2F1a

Genomic Locations for FAM24B Gene

Genomic Locations for FAM24B Gene
30,564 bases
Minus strand
30,564 bases
Minus strand

Genomic View for FAM24B Gene

Genes around FAM24B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM24B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM24B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM24B Gene

Proteins for FAM24B Gene

  • Protein details for FAM24B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM24B
    Protein Accession:
    Secondary Accessions:
    • Q5JPG1

    Protein attributes for FAM24B Gene

    94 amino acids
    Molecular mass:
    10147 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM24B Gene

Post-translational modifications for FAM24B Gene

No Post-translational modifications

Other Protein References for FAM24B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM24B Gene

Domains & Families for FAM24B Gene

Gene Families for FAM24B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM24B Gene


Suggested Antigen Peptide Sequences for FAM24B Gene

GenScript: Design optimal peptide antigens:
  • Protein FAM24B (FA24B_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM24 family.
  • Belongs to the FAM24 family.
genes like me logo Genes that share domains with FAM24B: view

Function for FAM24B Gene

Phenotypes From GWAS Catalog for FAM24B Gene

genes like me logo Genes that share phenotypes with FAM24B: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM24B

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM24B Gene

Localization for FAM24B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM24B Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM24B gene
Compartment Confidence
extracellular 4
plasma membrane 2

Gene Ontology (GO) - Cellular Components for FAM24B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM24B: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for FAM24B Gene

Pathways & Interactions for FAM24B Gene

PathCards logo

SuperPathways for FAM24B Gene

No Data Available

Interacting Proteins for FAM24B Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000357894 for FAM24B Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM24B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM24B Gene

Drugs & Compounds for FAM24B Gene

No Compound Related Data Available

Transcripts for FAM24B Gene

mRNA/cDNA for FAM24B Gene

8 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM24B

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM24B Gene

No ASD Table

Relevant External Links for FAM24B Gene

GeneLoc Exon Structure for

Expression for FAM24B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM24B Gene

mRNA expression in normal human tissues for FAM24B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FAM24B

SOURCE GeneReport for Unigene cluster for FAM24B Gene:


Evidence on tissue expression from TISSUES for FAM24B Gene

  • Lymph node(4.1)
genes like me logo Genes that share expression patterns with FAM24B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM24B Gene

Orthologs for FAM24B Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM24B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC100610674 30
  • 97.75 (n)
FAM24B 31
  • 95 (a)
(Mus musculus)
Mammalia Fam24a 31
  • 41 (a)
1700007K09Rik 31
  • 37 (a)
(Canis familiaris)
Mammalia -- 31
  • 36 (a)
Species where no ortholog for FAM24B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM24B Gene

Gene Tree for FAM24B (if available)
Gene Tree for FAM24B (if available)
Evolutionary constrained regions (ECRs) for FAM24B: view image

Paralogs for FAM24B Gene

Paralogs for FAM24B Gene

(1) SIMAP similar genes for FAM24B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM24B: view

Variants for FAM24B Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM24B Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
rs1891110 - p.Pro2Leu

Additional dbSNP identifiers (rs#s) for FAM24B Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM24B Gene

Variant ID Type Subtype PubMed ID
esv3624789 CNV gain 21293372
esv7958 CNV gain 19470904
nsv1054197 CNV loss 25217958
nsv832010 CNV gain 17160897

Variation tolerance for FAM24B Gene

Residual Variation Intolerance Score: 81.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.11; 2.39% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM24B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM24B Gene

Disorders for FAM24B Gene

Additional Disease Information for FAM24B

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for FAM24B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM24B Gene

Publications for FAM24B Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41 54
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 54
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 54

Products for FAM24B Gene

Sources for FAM24B Gene