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Aliases for FAM24A Gene

Aliases for FAM24A Gene

  • Family With Sequence Similarity 24 Member A 2 3 5
  • Family With Sequence Similarity 24, Member A 2

External Ids for FAM24A Gene

Previous GeneCards Identifiers for FAM24A Gene

  • GC10P124211
  • GC10P124660
  • GC10P118289

Summaries for FAM24A Gene

GeneCards Summary for FAM24A Gene

FAM24A (Family With Sequence Similarity 24 Member A) is a Protein Coding gene. An important paralog of this gene is FAM24B.

Additional gene information for FAM24A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM24A Gene

Genomics for FAM24A Gene

GeneHancer (GH) Regulatory Elements for FAM24A Gene

Promoters and enhancers for FAM24A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I122910 Promoter 0.5 EPDnew 550.8 -0.1 -110 0.1 FAM24A PIR46723 GC10M122775
GH10I123358 Enhancer 0.2 FANTOM5 29.8 +447.5 447515 0.2 FAM24A LOC105378531 GC10P123367
GH10I122953 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.3 +43.4 43366 1.7 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 C10orf88 PSTK BUB3 IKZF5 FAM24A GC10M122775
GH10I122930 Enhancer 0.8 ENCODE 0.3 +20.5 20459 1.6 HDAC1 PKNOX1 ATF1 NFIB NFRKB TCF12 ATF7 ZBTB11 CEBPB REST ACADSB IKZF5 FAM24A C10orf88 PSTK GC10M122775
GH10I122939 Enhancer 0.6 ENCODE 0.3 +29.1 29092 1.4 RFX1 CBFA2T3 MEF2D MITF NFIC ZNF184 ZNF512 PRDM1 C10orf88 ACADSB PSTK FAM24A GC10M122775
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM24A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the FAM24A gene promoter:

Genomic Locations for FAM24A Gene

Genomic Locations for FAM24A Gene
2,411 bases
Plus strand

Genomic View for FAM24A Gene

Genes around FAM24A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM24A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM24A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM24A Gene

Proteins for FAM24A Gene

  • Protein details for FAM24A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM24A
    Protein Accession:

    Protein attributes for FAM24A Gene

    105 amino acids
    Molecular mass:
    11258 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM24A Gene

Post-translational modifications for FAM24A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM24A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM24A Gene

Domains & Families for FAM24A Gene

Gene Families for FAM24A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM24A Gene


Suggested Antigen Peptide Sequences for FAM24A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM24 family.
  • Belongs to the FAM24 family.
genes like me logo Genes that share domains with FAM24A: view

Function for FAM24A Gene

Phenotypes From GWAS Catalog for FAM24A Gene

Phenotypes for FAM24A Gene

GenomeRNAi human phenotypes for FAM24A:
genes like me logo Genes that share phenotypes with FAM24A: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM24A Gene

Localization for FAM24A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM24A Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM24A gene
Compartment Confidence
extracellular 5
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FAM24A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM24A: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for FAM24A Gene

Pathways & Interactions for FAM24A Gene

SuperPathways for FAM24A Gene

No Data Available

Interacting Proteins for FAM24A Gene

Gene Ontology (GO) - Biological Process for FAM24A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM24A Gene

Drugs & Compounds for FAM24A Gene

No Compound Related Data Available

Transcripts for FAM24A Gene

mRNA/cDNA for FAM24A Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM24A Gene

Family with sequence similarity 24, member A:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM24A Gene

No ASD Table

Relevant External Links for FAM24A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM24A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM24A Gene

mRNA differential expression in normal tissues according to GTEx for FAM24A Gene

This gene is overexpressed in Testis (x52.9).

Protein differential expression in normal tissues from HIPED for FAM24A Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM24A Gene

Protein tissue co-expression partners for FAM24A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM24A Gene:


SOURCE GeneReport for Unigene cluster for FAM24A Gene:

genes like me logo Genes that share expression patterns with FAM24A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM24A Gene

Orthologs for FAM24A Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM24A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM24A 33 34
  • 98.73 (n)
(Mus musculus)
Mammalia Fam24a 34
  • 50 (a)
1700007K09Rik 34
  • 39 (a)
(Canis familiaris)
Mammalia -- 34
  • 35 (a)
Species where no ortholog for FAM24A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM24A Gene

Gene Tree for FAM24A (if available)
Gene Tree for FAM24A (if available)

Paralogs for FAM24A Gene

Paralogs for FAM24A Gene

(1) SIMAP similar genes for FAM24A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM24A: view

Variants for FAM24A Gene

Sequence variations from dbSNP and Humsavar for FAM24A Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000461453 -- 122,909,086(+) T/G upstream_transcript_variant
rs1001369865 -- 122,911,047(+) G/A intron_variant
rs1002142913 -- 122,910,921(+) T/C intron_variant
rs1003149398 -- 122,909,427(+) G/A upstream_transcript_variant
rs1003467661 -- 122,913,096(+) G/A 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM24A Gene

Variant ID Type Subtype PubMed ID
esv6242 OTHER inversion 19470904
nsv1054197 CNV loss 25217958
nsv832010 CNV gain 17160897

Variation tolerance for FAM24A Gene

Residual Variation Intolerance Score: 64% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.67; 14.21% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM24A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM24A Gene

Disorders for FAM24A Gene

Additional Disease Information for FAM24A

No disorders were found for FAM24A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM24A Gene

Publications for FAM24A Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 4 58

Products for FAM24A Gene

Sources for FAM24A Gene

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