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Aliases for FAM229A Gene

Aliases for FAM229A Gene

  • Family With Sequence Similarity 229 Member A 2 3 5
  • Family With Sequence Similarity 229, Member A 2
  • Protein FAM229A 3

External Ids for FAM229A Gene

Previous GeneCards Identifiers for FAM229A Gene

  • GC01M032827
  • GC01M032832

Summaries for FAM229A Gene

GeneCards Summary for FAM229A Gene

FAM229A (Family With Sequence Similarity 229 Member A) is a Protein Coding gene. An important paralog of this gene is FAM229B.

Additional gene information for FAM229A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM229A Gene

Genomics for FAM229A Gene

GeneHancer (GH) Regulatory Elements for FAM229A Gene

Promoters and enhancers for FAM229A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J032362 Promoter/Enhancer 1.1 EPDnew ENCODE 650.7 +1.8 1751 1 CTCF PKNOX1 NR2F1 ZBED1 RAD21 CCNT2 POLR2B POLR2A CTBP2 RBM22 FAM229A TSSK3 LOC105378629
GH01J032376 Promoter 0.5 EPDnew 650.4 -12.1 -12084 0.1 FAM229A LOC105378629 MARCKSL1 HDAC1 ENSG00000224066 IQCC EIF3I TMEM234 DCDC2B ENSG00000252450
GH01J032289 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 31.7 +73.0 72959 3.8 DMAP1 YY1 ZNF213 ZNF416 ZNF143 ZNF548 SP3 NFYC ZFP41 ZNF610 HDAC1 SNRNP40 RBBP4 TSSK3 TXLNA KHDRBS1 TMEM39B S100PBP FAM229A DCDC2B
GH01J032813 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 22 -453.0 -452964 7.3 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 S100PBP YARS RBBP4 TXLNA KHDRBS1 TSSK3 ZBTB8A TMEM39B EIF3I FAM229A
GH01J033126 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 30.3 -763.5 -763537 3.2 MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 ZNF548 SP3 GC01P033127 GC01P033128 GC01M033124 TSSK3 TXLNA RBBP4 FAM229A ZBTB8B S100PBP AZIN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM229A on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM229A Gene

Genomic Locations for FAM229A Gene
chr1:32,361,270-32,364,278
(GRCh38/hg38)
Size:
3,009 bases
Orientation:
Minus strand
chr1:32,826,871-32,829,879
(GRCh37/hg19)

Genomic View for FAM229A Gene

Genes around FAM229A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM229A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM229A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM229A Gene

Proteins for FAM229A Gene

  • Protein details for FAM229A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BQW9-F229A_HUMAN
    Recommended name:
    Protein FAM229A
    Protein Accession:
    H3BQW9

    Protein attributes for FAM229A Gene

    Size:
    127 amino acids
    Molecular mass:
    12972 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM229A Gene

Post-translational modifications for FAM229A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM229A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM229A Gene

Domains & Families for FAM229A Gene

Gene Families for FAM229A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM229A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

H3BQW9

UniProtKB/Swiss-Prot:

F229A_HUMAN :
  • Belongs to the FAM229 family.
Family:
  • Belongs to the FAM229 family.
genes like me logo Genes that share domains with FAM229A: view

No data available for Suggested Antigen Peptide Sequences for FAM229A Gene

Function for FAM229A Gene

Phenotypes From GWAS Catalog for FAM229A Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM229A

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM229A Gene

Localization for FAM229A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM229A Gene

Pathways & Interactions for FAM229A Gene

SuperPathways for FAM229A Gene

No Data Available

Interacting Proteins for FAM229A Gene

Gene Ontology (GO) - Biological Process for FAM229A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM229A Gene

Drugs & Compounds for FAM229A Gene

No Compound Related Data Available

Transcripts for FAM229A Gene

mRNA/cDNA for FAM229A Gene

(4) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM229A Gene

Family with sequence similarity 229, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM229A

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM229A Gene

No ASD Table

Relevant External Links for FAM229A Gene

GeneLoc Exon Structure for
FAM229A
ECgene alternative splicing isoforms for
FAM229A

Expression for FAM229A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM229A Gene

mRNA differential expression in normal tissues according to GTEx for FAM229A Gene

This gene is overexpressed in Testis (x16.9).

NURSA nuclear receptor signaling pathways regulating expression of FAM229A Gene:

FAM229A

SOURCE GeneReport for Unigene cluster for FAM229A Gene:

Hs.660539
genes like me logo Genes that share expression patterns with FAM229A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM229A Gene

Orthologs for FAM229A Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM229A Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia FAM229A 34
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC614396 33
  • 92.91 (n)
FAM229A 34
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM229A 33
  • 91.33 (n)
rat
(Rattus norvegicus)
Mammalia Fam229a 33
  • 89.16 (n)
mouse
(Mus musculus)
Mammalia Fam229a 16 34 33
  • 88.62 (n)
Species where no ortholog for FAM229A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM229A Gene

ENSEMBL:
Gene Tree for FAM229A (if available)
TreeFam:
Gene Tree for FAM229A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FAM229A: view image

Paralogs for FAM229A Gene

Paralogs for FAM229A Gene

(1) SIMAP similar genes for FAM229A Gene using alignment to 2 proteins:

  • F229A_HUMAN
  • H3BMD6_HUMAN
genes like me logo Genes that share paralogs with FAM229A: view

Variants for FAM229A Gene

Sequence variations from dbSNP and Humsavar for FAM229A Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000068694 -- 32,362,322(-) A/G upstream_transcript_variant
rs1000652777 -- 32,361,200(-) G/A downstream_transcript_variant
rs1000982482 -- 32,360,986(-) C/T downstream_transcript_variant
rs1002459355 -- 32,361,849(-) G/A coding_sequence_variant, synonymous_variant
rs1002472014 -- 32,360,794(-) A/G downstream_transcript_variant

Variation tolerance for FAM229A Gene

Gene Damage Index Score: 4.04; 60.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM229A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM229A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM229A Gene

Disorders for FAM229A Gene

Additional Disease Information for FAM229A

No disorders were found for FAM229A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM229A Gene

Publications for FAM229A Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 58

Products for FAM229A Gene

Sources for FAM229A Gene

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