Aliases for FAM204A Gene

Aliases for FAM204A Gene

  • Family With Sequence Similarity 204 Member A 2 3 5
  • Protein FAM204A 3 4
  • BA319I23.1 2 3
  • C10orf84 3 4
  • Family With Sequence Similarity 204, Member A 2
  • Chromosome 10 Open Reading Frame 84 2
  • FLJ13188 2
  • FAM204A 5

External Ids for FAM204A Gene

Previous HGNC Symbols for FAM204A Gene

  • C10orf84

Previous GeneCards Identifiers for FAM204A Gene

  • GC10M120065

Summaries for FAM204A Gene

GeneCards Summary for FAM204A Gene

FAM204A (Family With Sequence Similarity 204 Member A) is a Protein Coding gene.

Additional gene information for FAM204A Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM204A Gene

Genomics for FAM204A Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FAM204A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J118341 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.3 257 3.3 SP1 CTCF PRDM10 ZNF629 ZNF512 RFX1 POLR2A NFRKB FOS ZHX2 FAM204A LINC00867 lnc-NANOS1-11 lnc-FAM204A-6 piR-38941 RAB11FIP2
GH10J118373 Enhancer 0.7 Ensembl ENCODE 11.4 -31.8 -31773 1.4 PRDM10 ZIC2 ZSCAN4 SCRT2 JUND FOS SCRT1 ZNF195 FOSL2 FEZF1 FAM204A lnc-NANOS1-7 LINC00867 HSALNG0080977 PRLHR
GH10J118310 Enhancer 0.6 Ensembl 11.2 +31.1 31127 1.6 FOXA1 CEBPB FOXA2 EP300 GATA3 JUND RCOR1 CHD2 ZNF362 GATA2 lnc-RAB11FIP2-3 FAM204A piR-43106-031 lnc-FAM204A-6 RAB11FIP2
GH10J118381 Enhancer 0.4 UCNEbase 11.2 -39.7 -39691 0.3 ESR1 FAM204A HSALNG0080977 lnc-NANOS1-7 LINC00867 PRLHR
GH10J118316 Enhancer 0.3 UCNEbase 11.9 +25.1 25134 0.5 FAM204A lnc-RAB11FIP2-3 piR-43106-031 lnc-FAM204A-6 RAB11FIP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM204A on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FAM204A

Genomic Locations for FAM204A Gene

Genomic Locations for FAM204A Gene
chr10:118,297,925-118,342,328
(GRCh38/hg38)
Size:
44,404 bases
Orientation:
Minus strand
chr10:120,065,401-120,101,840
(GRCh37/hg19)
Size:
36,440 bases
Orientation:
Minus strand

Genomic View for FAM204A Gene

Genes around FAM204A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM204A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM204A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM204A Gene

Proteins for FAM204A Gene

  • Protein details for FAM204A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H8W3-F204A_HUMAN
    Recommended name:
    Protein FAM204A
    Protein Accession:
    Q9H8W3
    Secondary Accessions:
    • D3DRC6
    • Q5T373
    • Q9H5V5

    Protein attributes for FAM204A Gene

    Size:
    233 amino acids
    Molecular mass:
    27021 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM204A Gene

Post-translational modifications for FAM204A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM204A Gene

No data available for DME Specific Peptides for FAM204A Gene

Domains & Families for FAM204A Gene

Gene Families for FAM204A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM204A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM204A Gene

GenScript: Design optimal peptide antigens:
  • Protein FAM204A (F204A_HUMAN)
  • FLJ13188 protein (Q6IA51_HUMAN)
genes like me logo Genes that share domains with FAM204A: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FAM204A Gene

Function for FAM204A Gene

Gene Ontology (GO) - Molecular Function for FAM204A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23455924
genes like me logo Genes that share ontologies with FAM204A: view

Phenotypes for FAM204A Gene

genes like me logo Genes that share phenotypes with FAM204A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM204A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM204A Gene

Localization for FAM204A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM204A gene
Compartment Confidence
nucleus 4
cytoskeleton 2
plasma membrane 0
extracellular 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (3)
  • Nucleoplasm (3)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM204A Gene

Pathways & Interactions for FAM204A Gene

PathCards logo

SuperPathways for FAM204A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM204A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM204A Gene

Drugs & Compounds for FAM204A Gene

No Compound Related Data Available

Transcripts for FAM204A Gene

mRNA/cDNA for FAM204A Gene

2 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM204A

Alternative Splicing Database (ASD) splice patterns (SP) for FAM204A Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b
SP1: - - - -
SP2: - - - - -
SP3: - - - -
SP4: - - - -
SP5: - -
SP6: - - - - -
SP7: -
SP8: - - -
SP9: -
SP10: - -
SP11: -

Relevant External Links for FAM204A Gene

GeneLoc Exon Structure for
FAM204A

Expression for FAM204A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM204A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for FAM204A Gene

This gene is overexpressed in Uterus (46.4), Adipocyte (13.1), and Blymphocyte (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FAM204A Gene



Protein tissue co-expression partners for FAM204A Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FAM204A

SOURCE GeneReport for Unigene cluster for FAM204A Gene:

Hs.372309

Evidence on tissue expression from TISSUES for FAM204A Gene

  • Nervous system(3.8)
genes like me logo Genes that share expression patterns with FAM204A: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM204A Gene

Orthologs for FAM204A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM204A Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia FAM204A 30 31
  • 99.57 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia FAM204A 30 31
  • 88.13 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia FAM204A 30 31
  • 87.27 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia D19Ertd737e 30 31
  • 85.12 (n)
OneToOne
Fam204a 17
Rat
(Rattus norvegicus)
Mammalia Fam204a 30
  • 83.69 (n)
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 65 (a)
OneToMany
-- 31
  • 65 (a)
OneToMany
-- 31
  • 64 (a)
OneToMany
-- 31
  • 47 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia FAM204A 31
  • 64 (a)
OneToOne
Chicken
(Gallus gallus)
Aves FAM204A 30 31
  • 63.77 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia FAM204A 31
  • 55 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii fam204a 30 31
  • 56.98 (n)
OneToOne
Dr.18811 30
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.900 31
  • 29 (a)
OneToOne
Species where no ortholog for FAM204A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for FAM204A Gene

ENSEMBL:
Gene Tree for FAM204A (if available)
TreeFam:
Gene Tree for FAM204A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FAM204A: view image

Paralogs for FAM204A Gene

(1) SIMAP similar genes for FAM204A Gene using alignment to 3 proteins:

  • F204A_HUMAN
  • F2Z2Y3_HUMAN
  • Q5T374_HUMAN

Pseudogenes.org Pseudogenes for FAM204A Gene

genes like me logo Genes that share paralogs with FAM204A: view

No data available for Paralogs for FAM204A Gene

Variants for FAM204A Gene

Additional dbSNP identifiers (rs#s) for FAM204A Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM204A Gene

Variant ID Type Subtype PubMed ID
esv2741561 CNV deletion 23290073
esv2741572 CNV deletion 23290073
esv2741584 CNV deletion 23290073
esv3624687 CNV loss 21293372

Variation tolerance for FAM204A Gene

Residual Variation Intolerance Score: 40% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.34; 7.58% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM204A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM204A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM204A Gene

Disorders for FAM204A Gene

No disorders were found for FAM204A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM204A Gene

Publications for FAM204A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  4. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3

Products for FAM204A Gene

Sources for FAM204A Gene