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Aliases for FAM200A Gene

Aliases for FAM200A Gene

  • Family With Sequence Similarity 200 Member A 2 3 5
  • C7orf38 3 4
  • Family With Sequence Similarity 200, Member A 2
  • Chromosome 7 Open Reading Frame 38 2
  • Protein FAM200A 3

External Ids for FAM200A Gene

Previous HGNC Symbols for FAM200A Gene

  • C7orf38

Previous GeneCards Identifiers for FAM200A Gene

  • GC07M099143
  • GC07M093780

Summaries for FAM200A Gene

Entrez Gene Summary for FAM200A Gene

  • This gene encodes a protein of unknown function. The protein is weakly similar to transposase-like proteins in human and mouse. [provided by RefSeq, Jul 2008]

GeneCards Summary for FAM200A Gene

FAM200A (Family With Sequence Similarity 200 Member A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is FAM200B.

Gene Wiki entry for FAM200A Gene

Additional gene information for FAM200A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM200A Gene

Genomics for FAM200A Gene

GeneHancer (GH) Regulatory Elements for FAM200A Gene

Promoters and enhancers for FAM200A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J099557 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 650.7 -1.6 -1591 7.9 ZFP64 DMAP1 YY1 E2F8 ZNF143 SP3 MEF2D SSRP1 GLIS1 NBN ZNF655 FAM200A ZSCAN25 ZNF3 TRIM4 PTCD1 PPP1R35 TRRAP STAG3L5P ZNF394
GH07J099551 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 650.4 +7.4 7447 1.9 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B LOC105375422 FAM200A ZSCAN25 PPP1R35 MEPCE PTCD1 TRRAP TRIM4 ZNF655 ZNF3
GH07J100427 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 12.4 -873.8 -873804 10.8 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PPP1R35 MEPCE ZCWPW1 PIR54054 ZSCAN25 SRRT TRIM4 GIGYF1 ZNF3 PILRA
GH07J099471 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 12.3 +86.8 86791 3 CLOCK DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC ZNF610 GLIS1 ZNF789 ZSCAN25 PPP1R35 PTCD1 TRRAP MEPCE TRIM4 STAG3L5P ZNF655 AP4M1
GH07J099616 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.4 -58.9 -58874 4.5 DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC MEF2D SSRP1 ZNF585B ZSCAN25 TRRAP ZNF3 AP4M1 TRIM4 ZNF655 PTCD1 PPP1R35 ENSG00000242798 MEPCE
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM200A on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM200A Gene

Genomic Locations for FAM200A Gene
13,096 bases
Minus strand
12,237 bases
Minus strand

Genomic View for FAM200A Gene

Genes around FAM200A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM200A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM200A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM200A Gene

Proteins for FAM200A Gene

  • Protein details for FAM200A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM200A
    Protein Accession:
    Secondary Accessions:
    • A4D293
    • A8K3V9
    • B2RD92
    • C9J6A8
    • D6W5T2
    • Q8N9P3

    Protein attributes for FAM200A Gene

    573 amino acids
    Molecular mass:
    66276 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM200A Gene

Post-translational modifications for FAM200A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM200A Gene

No data available for DME Specific Peptides for FAM200A Gene

Domains & Families for FAM200A Gene

Gene Families for FAM200A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM200A Gene


Suggested Antigen Peptide Sequences for FAM200A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM200 family.
  • Belongs to the FAM200 family.
genes like me logo Genes that share domains with FAM200A: view

Function for FAM200A Gene

Phenotypes From GWAS Catalog for FAM200A Gene

Gene Ontology (GO) - Molecular Function for FAM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003677 DNA binding IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM200A: view

Phenotypes for FAM200A Gene

genes like me logo Genes that share phenotypes with FAM200A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM200A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM200A Gene

Localization for FAM200A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM200A Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM200A gene
Compartment Confidence
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for FAM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IBA --
GO:0005737 cytoplasm IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM200A: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for FAM200A Gene

Pathways & Interactions for FAM200A Gene

SuperPathways for FAM200A Gene

No Data Available

Interacting Proteins for FAM200A Gene

Gene Ontology (GO) - Biological Process for FAM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with FAM200A: view

No data available for Pathways by source and SIGNOR curated interactions for FAM200A Gene

Drugs & Compounds for FAM200A Gene

No Compound Related Data Available

Transcripts for FAM200A Gene

mRNA/cDNA for FAM200A Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(32) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM200A Gene

Family with sequence similarity 200, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM200A

Alternative Splicing Database (ASD) splice patterns (SP) for FAM200A Gene

No ASD Table

Relevant External Links for FAM200A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM200A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM200A Gene

Protein differential expression in normal tissues from HIPED for FAM200A Gene

This gene is overexpressed in Platelet (28.7), Fetal testis (18.1), Fetal heart (14.8), and Liver (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM200A Gene

Protein tissue co-expression partners for FAM200A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM200A Gene:


SOURCE GeneReport for Unigene cluster for FAM200A Gene:


Evidence on tissue expression from TISSUES for FAM200A Gene

  • Nervous system(4.2)
  • Adrenal gland(4.1)
genes like me logo Genes that share expression patterns with FAM200A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM200A Gene

Orthologs for FAM200A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM200A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM200A 34 33
  • 99.36 (n)
(Canis familiaris)
Mammalia FAM200A 34 33
  • 89.71 (n)
(Bos Taurus)
Mammalia FAM200A 33
  • 88.37 (n)
(Mus musculus)
Mammalia 2410018M08Rik 34
  • 25 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 24 (a)
(Danio rerio)
Actinopterygii CR388095.1 34
  • 31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 22 (a)
Species where no ortholog for FAM200A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM200A Gene

Gene Tree for FAM200A (if available)
Gene Tree for FAM200A (if available)
Evolutionary constrained regions (ECRs) for FAM200A: view image

Paralogs for FAM200A Gene

Paralogs for FAM200A Gene

(5) SIMAP similar genes for FAM200A Gene using alignment to 2 proteins:

  • F200A_HUMAN
  • J3QT35_HUMAN
genes like me logo Genes that share paralogs with FAM200A: view

Variants for FAM200A Gene

Sequence variations from dbSNP and Humsavar for FAM200A Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000224193 -- 99,552,159(-) G/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000281398 -- 99,552,014(-) A/C 5_prime_UTR_variant, intron_variant
rs1001229982 -- 99,553,734(-) G/A genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001280907 -- 99,553,468(-) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001399898 -- 99,547,197(-) T/C coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM200A Gene

Variant ID Type Subtype PubMed ID
esv2507396 CNV insertion 19546169
nsv1117743 CNV deletion 24896259

Variation tolerance for FAM200A Gene

Gene Damage Index Score: 2.55; 44.36% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM200A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM200A Gene

Disorders for FAM200A Gene

Additional Disease Information for FAM200A

No disorders were found for FAM200A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM200A Gene

Publications for FAM200A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 3 4 58
  4. Interspersed repeats and other mementos of transposable elements in mammalian genomes. (PMID: 10607616) Smit AF (Current opinion in genetics & development 1999) 2 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for FAM200A Gene

Sources for FAM200A Gene

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