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Aliases for FAM187A Gene

Aliases for FAM187A Gene

  • Family With Sequence Similarity 187 Member A 2 3 5
  • Family With Sequence Similarity 187, Member A 2

External Ids for FAM187A Gene

Previous GeneCards Identifiers for FAM187A Gene

  • GC00U922894
  • GC17P042979

Summaries for FAM187A Gene

GeneCards Summary for FAM187A Gene

FAM187A (Family With Sequence Similarity 187 Member A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is CCDC103.

Additional gene information for FAM187A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM187A Gene

Genomics for FAM187A Gene

GeneHancer (GH) Regulatory Elements for FAM187A Gene

Promoters and enhancers for FAM187A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I044898 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 567 +0.6 561 4.1 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 EFTUD2 FAM187A CCDC103 GJC1 TMUB2 HEXIM1 ASB16-AS1 ENSG00000267344 PIR50226
GH17I044827 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 13.8 -69.8 -69808 3.9 SIN3A GLI4 ZNF2 ETS1 GLIS2 KLF7 RUNX3 SP3 REST TSHZ1 GC17M044778 GJC1 FAM187A ENSG00000267344
GH17I044793 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.6 -104.5 -104466 2.9 ATF1 PKNOX1 INSM2 KLF17 SIN3A GLI4 ZBTB40 ZNF366 FOS ETV6 GC17P044797 UBTF FAM187A ASB16-AS1 EFTUD2 GRN FMNL1 ENSG00000267405 ENSG00000267505 GC17M044778
GH17I044904 Enhancer 1.1 Ensembl ENCODE 16.3 +6.6 6564 3 ATF1 TCF12 GATA2 FOS ATF7 NCOA1 ZNF592 MBD2 MEF2D ATF4 GC17M044904 GC17P044905 GC17P044908 PIR49404 EFTUD2 FAM187A UBTF ASB16-AS1 CCDC103 GFAP
GH17I045020 Enhancer 1.4 Ensembl ENCODE dbSUPER 11.6 +121.7 121712 2.5 ATF1 ZFP64 ARID4B SIN3A DMAP1 ZNF48 ZNF207 ZNF143 ATF7 PAF1 DCAKD NMT1 C1QL1 GFAP CCDC103 EFTUD2 FAM187A KIF18B HEXIM2 ENSG00000224505
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM187A on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM187A Gene

Genomic Locations for FAM187A Gene
5,679 bases
Plus strand

Genomic View for FAM187A Gene

Genes around FAM187A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM187A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM187A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for FAM187A Gene

Proteins for FAM187A Gene

  • Protein details for FAM187A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ig-like V-type domain-containing protein FAM187A
    Protein Accession:

    Protein attributes for FAM187A Gene

    413 amino acids
    Molecular mass:
    47349 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM187A Gene

Post-translational modifications for FAM187A Gene

No Post-translational modifications

Other Protein References for FAM187A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM187A Gene

Domains & Families for FAM187A Gene

Gene Families for FAM187A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for FAM187A Gene

Suggested Antigen Peptide Sequences for FAM187A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM187 family.
  • Belongs to the FAM187 family.
genes like me logo Genes that share domains with FAM187A: view

Function for FAM187A Gene

Phenotypes From GWAS Catalog for FAM187A Gene

miRNA for FAM187A Gene

miRTarBase miRNAs that target FAM187A

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM187A Gene

Localization for FAM187A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM187A Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM187A gene
Compartment Confidence
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for FAM187A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM187A: view

Pathways & Interactions for FAM187A Gene

SuperPathways for FAM187A Gene

No Data Available

Interacting Proteins for FAM187A Gene

Gene Ontology (GO) - Biological Process for FAM187A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM187A Gene

Drugs & Compounds for FAM187A Gene

No Compound Related Data Available

Transcripts for FAM187A Gene

mRNA/cDNA for FAM187A Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM187A Gene

No ASD Table

Relevant External Links for FAM187A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM187A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM187A Gene

mRNA expression in normal human tissues for FAM187A Gene

Protein differential expression in normal tissues from HIPED for FAM187A Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM187A Gene

Protein tissue co-expression partners for FAM187A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM187A Gene:


Evidence on tissue expression from TISSUES for FAM187A Gene

  • Nervous system(2)
genes like me logo Genes that share expression patterns with FAM187A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM187A Gene

Orthologs for FAM187A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM187A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM187A 34
  • 97 (a)
(Bos Taurus)
Mammalia FAM187A 34
  • 84 (a)
(Canis familiaris)
Mammalia FAM187A 34
  • 84 (a)
(Mus musculus)
Mammalia Fam187a 34
  • 78 (a)
(Monodelphis domestica)
Mammalia FAM187A 34
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia FAM187A 34
  • 67 (a)
(Gallus gallus)
Aves FAM187A 34
  • 54 (a)
(Anolis carolinensis)
Reptilia FAM187A 34
  • 56 (a)
Species where no ortholog for FAM187A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM187A Gene

Gene Tree for FAM187A (if available)
Gene Tree for FAM187A (if available)

Paralogs for FAM187A Gene

Paralogs for FAM187A Gene

genes like me logo Genes that share paralogs with FAM187A: view

Variants for FAM187A Gene

Variation tolerance for FAM187A Gene

Gene Damage Index Score: 10.08; 90.17% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM187A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for FAM187A Gene

Disorders for FAM187A Gene

Additional Disease Information for FAM187A

No disorders were found for FAM187A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM187A Gene

Publications for FAM187A Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for FAM187A Gene

Sources for FAM187A Gene

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