Aliases for FAM182B Gene

Subcategory (RNA class) for FAM182B Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for FAM182B Gene

  • Family With Sequence Similarity 182 Member B 2 3 5
  • FAM182B 2 5
  • Family With Sequence Similarity 182, Member B 2
  • NONHSAG031540.2 91
  • Protein FAM182B 4
  • Lnc-FAM182B-8 165
  • HSALNG0129408 164
  • HSALNG0129415 164

External Ids for FAM182B Gene

Previous GeneCards Identifiers for FAM182B Gene

  • GC20M025692
  • GC20M025744

Summaries for FAM182B Gene

GeneCards Summary for FAM182B Gene

FAM182B (Family With Sequence Similarity 182 Member B) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for FAM182B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM182B Gene

Genomics for FAM182B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FAM182B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J025861 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl CraniofacialAtlas 639.6 +6.0 6024 3.2 PRDM10 TFE3 RFX1 NFKBIZ ZNF692 TARDBP ZIC2 ZSCAN4 REST TRIM22 FAM182B NANP ZNF337 ENSG00000250090 lnc-GINS1-3 LOC101926935
GH20J025868 Promoter 1.3 EPDnew Ensembl CraniofacialAtlas 639.7 -0.3 -258 1 NRF1 GABPB1 ZFP91 ZNF48 EZH2 FAM182B piR-60775 RNU6ATAC17P ZNF337
GH20J025860 Promoter 1.2 EPDnew Ensembl 631.3 +8.1 8124 0.6 PRDM10 RFX1 ZNF143 EZH2 NRF1 RFX3 RELB ZBTB26 ZBTB2 PKNOX1 FAM182B ENSG00000250090 lnc-GINS1-3 LOC101926935 ZNF337
GH20J026009 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 36.6 -142.2 -142176 2.8 CEBPG CREB1 PRDM10 ZNF629 ZNF692 POLR2A TARDBP PRDM1 ZNF143 RFX1 ENSG00000231081 ENSG00000287569 LOC100134868 FAM182B ABHD12 NANP NINL ZNF337 FAM182A
GH20J025987 Promoter 0.8 CraniofacialAtlas 49.4 -118.8 -118840 0.6 ZBTB33 PRDM10 NRF1 MGA ZBTB2 CTCF IKZF1 ZNF335 ZNF687 MAZ FAM182A FAM182B NINL piR-40097 ZNF337
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM182B on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for FAM182B Gene

Genomic Locations for FAM182B Gene
chr20:25,762,384-25,868,225
(GRCh38/hg38)
Size:
105,842 bases
Orientation:
Minus strand
chr20:25,744,102-25,848,861
(GRCh37/hg19)
Size:
104,760 bases
Orientation:
Minus strand

Genomic View for FAM182B Gene

Genes around FAM182B on UCSC Golden Path with GeneCards custom track
FAM182B in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
FAM182B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM182B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM182B Gene

Proteins for FAM182B Gene

  • Protein details for FAM182B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T319-F182B_HUMAN
    Recommended name:
    Protein FAM182B
    Protein Accession:
    Q5T319
    Secondary Accessions:
    • Q4G0Q1

    Protein attributes for FAM182B Gene

    Size:
    152 amino acids
    Molecular mass:
    15775 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Alternative splice isoforms for FAM182B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM182B Gene

Post-translational modifications for FAM182B Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM182B Gene

Domains & Families for FAM182B Gene

Gene Families for FAM182B Gene

Protein Domains for FAM182B Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM182B Gene

GenScript: Design optimal peptide antigens:
  • Protein FAM182B (F182B_HUMAN)
genes like me logo Genes that share domains with FAM182B: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FAM182B Gene

Function for FAM182B Gene

Phenotypes From GWAS Catalog for FAM182B Gene

genes like me logo Genes that share phenotypes with FAM182B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM182B Gene

Localization for FAM182B Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM182B gene
Compartment Confidence
extracellular 1
nucleus 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM182B Gene

Pathways & Interactions for FAM182B Gene

PathCards logo

SuperPathways for FAM182B Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM182B Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for FAM182B Gene

Drugs & Compounds for FAM182B Gene

No Compound Related Data Available

Transcripts for FAM182B Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for FAM182B Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BB79_9606 lncRNA 5481 5

HGNC: 34503,

RefSeq: NR_026714,

LncBook: HSALNT0266051,

LNCipedia: lnc-FAM182B-8:7,

NONCODE: NONHSAT079187.2,

URS0000D6E733_9606 lncRNA 992 2

Ensembl: ENST00000478164 (view in UCSC) ,

LNCipedia: lnc-FAM182B-8:3,

URS00008C2F38_9606 lncRNA 832 2

Ensembl: ENST00000582267 (view in UCSC) ,

LNCipedia: lnc-FAM182B-8:1,

URS00008C3CA1_9606 lncRNA 610 2

Ensembl: ENST00000584356 (view in UCSC) ,

LNCipedia: lnc-FAM182B-8:4,

URS0000D58AD5_9606 lncRNA 605 2

Ensembl: ENST00000424021 (view in UCSC) ,

LNCipedia: lnc-FAM182B-8:2,

FAM182B in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for FAM182B Gene

3 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM182B Gene

No ASD Table

Relevant External Links for FAM182B Gene

GeneLoc Exon Structure for
FAM182B

Expression for FAM182B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM182B Gene

mRNA differential expression in normal tissues according to GTEx for FAM182B Gene

This gene is overexpressed in Testis (x6.5).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FAM182B

SOURCE GeneReport for Unigene cluster for FAM182B Gene:

Hs.682103

Evidence on tissue expression from TISSUES for FAM182B Gene

  • Lung(4.8)
  • Nervous system(3.8)
  • Liver(3.5)
  • Eye(2)
genes like me logo Genes that share expression patterns with FAM182B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM182B Gene

Orthologs for FAM182B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM182B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 31
  • 86 (a)
OneToMany
-- 31
  • 84 (a)
OneToMany
Species where no ortholog for FAM182B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for FAM182B Gene

ENSEMBL:
Gene Tree for FAM182B (if available)
TreeFam:
Gene Tree for FAM182B (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FAM182B: view image

Paralogs for FAM182B Gene

(1) SIMAP similar genes for FAM182B Gene using alignment to 3 proteins:

  • F182B_HUMAN
  • F6T327_HUMAN
  • J3QS56_HUMAN
genes like me logo Genes that share paralogs with FAM182B: view

No data available for Paralogs for FAM182B Gene

Variants for FAM182B Gene

Additional dbSNP identifiers (rs#s) for FAM182B Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM182B Gene

Variant ID Type Subtype PubMed ID
dgv2231n106 CNV duplication 24896259
dgv2415e59 CNV duplication 20981092
dgv2416e59 CNV duplication 20981092
dgv4291n100 CNV gain 25217958
dgv7521n54 CNV loss 21841781
esv23664 CNV gain+loss 19812545
esv2758790 CNV gain+loss 17122850
esv3352094 CNV duplication 20981092
esv3352879 CNV duplication 20981092
esv3364413 CNV duplication 20981092
esv3388004 CNV duplication 20981092
esv3429256 CNV duplication 20981092
esv3449831 CNV duplication 20981092
esv3575367 CNV gain 25503493
esv990797 CNV gain 20482838
nsv1062442 CNV gain 25217958
nsv1078479 CNV duplication 25765185
nsv1078480 CNV duplication 25765185
nsv1078481 CNV duplication 25765185
nsv1110365 CNV duplication 24896259
nsv1110366 CNV duplication 24896259
nsv1115599 CNV duplication 24896259
nsv1115600 CNV duplication 24896259
nsv1138935 CNV deletion 24896259
nsv1141963 OTHER inversion 24896259
nsv1145771 CNV duplication 26484159
nsv1147282 CNV duplication 26484159
nsv1152348 CNV duplication 26484159
nsv1153810 OTHER inversion 26484159
nsv470545 CNV gain 18288195
nsv510784 CNV deletion 20534489
nsv522873 CNV gain 19592680
nsv585749 CNV loss 21841781
nsv7340 OTHER inversion 18451855
nsv820681 CNV duplication 20802225
nsv953010 CNV duplication 24416366
nsv9794 CNV loss 18304495
nsv979422 CNV duplication 23825009

Variation tolerance for FAM182B Gene

Gene Damage Index Score: 0.85; 17.79% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM182B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM182B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM182B Gene

Disorders for FAM182B Gene

No disorders were found for FAM182B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM182B Gene

Publications for FAM182B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for FAM182B Gene

Sources for FAM182B Gene