Aliases for FAM160B2 Gene
Aliases for FAM160B2 Gene
External Ids for FAM160B2 Gene
- HGNC: 16492
- Entrez Gene: 64760
- Ensembl: ENSG00000158863
- UniProtKB: Q86V87
Previous HGNC Symbols for FAM160B2 Gene
- RAI16
Previous GeneCards Identifiers for FAM160B2 Gene
- GC08P022003
- GC08P020466
- GC08P021947
Summaries for FAM160B2 Gene
GeneCards Summary for FAM160B2 Gene
FAM160B2 (Family With Sequence Similarity 160 Member B2) is a Protein Coding gene. An important paralog of this gene is FAM160B1.
Additional gene information for FAM160B2 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM160B2 Gene
Genomics for FAM160B2 Gene
GeneHancer (GH) Regulatory Elements for FAM160B2 Gene
Promoters and enhancers for FAM160B2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around FAM160B2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the FAM160B2 gene promoter:
Regulatory Element Products
Genomic Locations for FAM160B2 Gene
Genomic Locations for FAM160B2 Gene
- chr8:22,089,159-22,104,898
- (GRCh38/hg38)
- Size:
- 15,740 bases
- Orientation:
- Plus strand
- chr8:21,946,670-21,962,409
- (GRCh37/hg19)
Genomic View for FAM160B2 Gene
Genes around FAM160B2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p21.3 by Ensembl
- 8p21.3 by Entrez Gene
- 8p21.3 by HGNC
FAM160B2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM160B2 Gene
Proteins for FAM160B2 Gene
-
Protein details for FAM160B2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86V87-F16B2_HUMAN
- Recommended name:
- Protein FAM160B2
- Protein Accession:
- Q86V87
- B2RDQ5
- B3KNX1
- Q2M211
- Q71JB5
- Q7L3J6
- Q969T0
- Q9H6W4
Protein attributes for FAM160B2 Gene
- Size:
- 743 amino acids
- Molecular mass:
- 82340 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH52237.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI12148.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAI12148.2; Type=Frameshift; Positions=291; Evidence={ECO:0000305}; Sequence=AAQ06676.1; Type=Frameshift; Positions=258, 727; Evidence={ECO:0000305}; Sequence=BAB15137.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG38002.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG51483.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for FAM160B2 Gene
Post-translational modifications for FAM160B2 Gene
No Post-translational modifications
Other Protein References for FAM160B2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM160B2
-
Abcam antibodies for FAM160B2
- Invitrogen Antibodies for FAM160B2
- GeneTex FAM160B2 antibody for FAM160B2
Protein Products
-
OriGene Purified Proteins for FAM160B2
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM160B2
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- Search GeneTex for Proteins for FAM160B2
-
Abcam proteins for FAM160B2
Assay Products
No data available for DME Specific Peptides for FAM160B2 Gene
Domains & Families for FAM160B2 Gene
Gene Families for FAM160B2 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for FAM160B2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM160B2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q86V87- Family:
-
- Belongs to the UPF0518 family.
Function for FAM160B2 Gene
Phenotypes From GWAS Catalog for FAM160B2 Gene
Phenotypes for FAM160B2 Gene
- GenomeRNAi human phenotypes for FAM160B2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM160B2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM160B2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM160B2 gene
- Search ViGene Biosciences for FAM160B2
CRISPR Products
-
OriGene CRISPR knockouts for FAM160B2
- genomics-online: gRNA clones - Search results for available FAM160B2 gene related products
- Applied Biological Materials CRISPR for FAM160B2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM160B2
- GenScript: Design CRISPR guide RNA sequences for FAM160B2
miRNA for FAM160B2 Gene
- miRTarBase miRNAs that target FAM160B2
miRNA Products
- Search ViGene Biosciences for FAM160B2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for FAM160B2
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- genomics-online: shRNA clones - Search results for available FAM160B2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM160B2 gene
Clone Products
-
OriGene ORF clones in human for FAM160B2
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM160B2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM160B2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FAM160B2 gene related products
- orf clones - Search results for available FAM160B2 gene related products
- Applied Biological Materials Clones for FAM160B2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for FAM160B2
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM160B2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM160B2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM160B2 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM160B2 Gene
Localization for FAM160B2 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| peroxisome | 1 |
- Cytosol (2)
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM160B2 Gene
Pathways & Interactions for FAM160B2 Gene
No Data Available
No data available for Pathways by source and SIGNOR curated interactions for FAM160B2 Gene
Transcripts for FAM160B2 Gene
mRNA/cDNA for FAM160B2 Gene
- (9) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (214) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM160B2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM160B2
- genomics-online: gRNA clones - Search results for available FAM160B2 gene related products
- Applied Biological Materials CRISPR for FAM160B2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM160B2
- GenScript: Design CRISPR guide RNA sequences for FAM160B2
miRNA Products
- Search ViGene Biosciences for FAM160B2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for FAM160B2
- Browse OriGene Inhibitory RNA Products For FAM160B2
- genomics-online: shRNA clones - Search results for available FAM160B2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM160B2 gene
Clone Products
-
OriGene ORF clones in human for FAM160B2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FAM160B2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for FAM160B2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM160B2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FAM160B2 gene related products
- orf clones - Search results for available FAM160B2 gene related products
- Applied Biological Materials Clones for FAM160B2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: |
| ExUns: | 17b | · | 17c | · | 17d |
|---|---|---|---|---|---|
| SP1: | |||||
| SP2: | |||||
| SP3: | |||||
| SP4: | |||||
| SP5: | |||||
| SP6: | |||||
| SP7: | |||||
| SP8: | |||||
| SP9: | |||||
| SP10: |
Expression for FAM160B2 Gene
This gene is overexpressed in Bone (62.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM160B2 Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM160B2 Gene:
FAM160B2SOURCE GeneReport for Unigene cluster for FAM160B2 Gene:
Hs.491223Evidence on tissue expression from TISSUES for FAM160B2 Gene
- Nervous system(3.2)
- Spleen(2)
Primer Products
-
OriGene qPCR primer pairs for FAM160B2
- genomics-online: primer clones - Search results for available FAM160B2 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM160B2 Gene
Orthologs for FAM160B2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM160B2 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM160B2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM160B2 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam160b2 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam160b2 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAM160B2 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM160B2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FAM160B2 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FAM160B2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam160b2 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fam160b2 33 34 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.5399 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for FAM160B2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM160B2 Gene
(1) SIMAP similar genes for FAM160B2 Gene using alignment to 2 proteins:
Variants for FAM160B2 Gene
| SNP ID | Clin | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000278986 | -- | 22,093,598(+) | A/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000409059 | -- | 22,098,300(+) | G/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000814521 | -- | 22,088,499(+) | C/T | upstream_transcript_variant | |
| rs1000886131 | -- | 22,093,500(+) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000935564 | -- | 22,087,160(+) | T/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv951112 | CNV | deletion | 24416366 |
| nsv831264 | CNV | gain+loss | 17160897 |
| nsv831263 | CNV | loss | 17160897 |
| nsv610765 | CNV | loss | 21841781 |
| nsv610764 | CNV | loss | 21841781 |
| nsv528590 | CNV | loss | 19592680 |
| nsv470204 | CNV | loss | 18288195 |
| nsv465613 | CNV | loss | 19166990 |
| esv2759604 | CNV | loss | 17122850 |
| esv2736745 | CNV | deletion | 23290073 |
| esv1008033 | CNV | deletion | 20482838 |
| dgv881n27 | CNV | loss | 19166990 |
| dgv450n21 | CNV | loss | 19592680 |
| dgv12055n54 | CNV | loss | 21841781 |
| dgv12054n54 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
55.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.00;
90.00% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FAM160B2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM160B2 Gene
Disorders for FAM160B2 Gene
Additional Disease Information for FAM160B2
No disorders were found for FAM160B2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM160B2 Gene
Publications for FAM160B2 Gene
- Retinoic acid induced 16 enhances tumorigenesis and serves as a novel tumor marker for hepatocellular carcinoma. (PMID: 22971576) Wang W … Qi ZT (Carcinogenesis 2012) 2 3 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Are gene expression microarray analyses reliable? A review of studies of retinoic acid responsive genes. (PMID: 15626329) van der Spek PJ … Walker MG (Genomics, proteomics & bioinformatics 2003) 2 3 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- Anchoring of both PKA-RIIα and 14-3-3θ regulates retinoic acid induced 16 mediated phosphorylation of heat shock protein 70. (PMID: 25900241) Ding CL … Wang W (Oncotarget 2015) 3 58
Products for FAM160B2 Gene
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- Invitrogen Antibodies for FAM160B2
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- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM160B2
- VectorBuilder custom plasmid, inducible vectors for FAM160B2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM160B2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- GeneTex FAM160B2 antibody for FAM160B2
- Search GeneTex for Proteins for FAM160B2
- ViGene Biosciences adenoviral particle packaged cDNA for FAM160B2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM160B2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM160B2 gene
- Search ViGene Biosciences for FAM160B2
- Browse Santa Cruz Biotechnology (SCBT) Antibodies
- Search Santa Cruz Biotechnology (SCBT) for FAM160B2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FAM160B2
- Horizon Cell Lines for FAM160B2
- genomics-online: cdna clones - Search results for available FAM160B2 gene related products
- orf clones - Search results for available FAM160B2 gene related products
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- genomics-online: primer clones - Search results for available FAM160B2 gene related products
- genomics-online: shRNA clones - Search results for available FAM160B2 gene related products
Sources for FAM160B2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
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