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Aliases for FAM155A Gene

Aliases for FAM155A Gene

  • Family With Sequence Similarity 155 Member A 2 3 5
  • Family With Sequence Similarity 155, Member A 2

External Ids for FAM155A Gene

Previous GeneCards Identifiers for FAM155A Gene

  • GC13M106619
  • GC13M107820
  • GC13M088412

Summaries for FAM155A Gene

GeneCards Summary for FAM155A Gene

FAM155A (Family With Sequence Similarity 155 Member A) is a Protein Coding gene. An important paralog of this gene is FAM155B.

Additional gene information for FAM155A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM155A Gene

Genomics for FAM155A Gene

GeneHancer (GH) Regulatory Elements for FAM155A Gene

Promoters and enhancers for FAM155A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I107865 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE 564.9 +0.1 139 2.8 CTCF MXI1 SUZ12 SIN3A RAD21 HIC1 ZNF335 ZFHX2 GLIS2 POLR2A FAM155A LIG4 FAM155A-IT1
GH13I107868 Enhancer 0.6 FANTOM5 556.4 -1.5 -1497 0.3 ZNF335 CTCF ZFHX2 SUZ12 EZH2 FAM155A ENSG00000274718 LIG4
GH13I107842 Enhancer 0.5 ENCODE 13.1 +24.3 24315 0.4 GATA3 JUND POLR2A FOS FAM155A FAM155A-IT1
GH13I107366 Enhancer 0.5 ENCODE dbSUPER 5.6 +499.9 499878 0.9 JUN FAM155A SNORD31B GC13M107322 PIR34139
GH13I107843 Enhancer 0.2 ENCODE 13.1 +23.9 23887 0.2 FAM155A FAM155A-IT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM155A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the FAM155A gene promoter:

Genomic Locations for FAM155A Gene

Genomic Locations for FAM155A Gene
703,746 bases
Minus strand

Genomic View for FAM155A Gene

Genes around FAM155A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM155A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM155A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM155A Gene

Proteins for FAM155A Gene

  • Protein details for FAM155A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein FAM155A
    Protein Accession:
    Secondary Accessions:
    • B2RUV1
    • B7Z334

    Protein attributes for FAM155A Gene

    458 amino acids
    Molecular mass:
    51493 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM155A Gene

Post-translational modifications for FAM155A Gene

Other Protein References for FAM155A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM155A Gene

Domains & Families for FAM155A Gene

Gene Families for FAM155A Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for FAM155A Gene

Suggested Antigen Peptide Sequences for FAM155A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM155 family.
  • Belongs to the FAM155 family.
genes like me logo Genes that share domains with FAM155A: view

Function for FAM155A Gene

Phenotypes From GWAS Catalog for FAM155A Gene

Gene Ontology (GO) - Molecular Function for FAM155A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015275 contributes_to stretch-activated, cation-selective, calcium channel activity IBA --
genes like me logo Genes that share ontologies with FAM155A: view

Phenotypes for FAM155A Gene

GenomeRNAi human phenotypes for FAM155A:
genes like me logo Genes that share phenotypes with FAM155A: view

Animal Model Products

miRNA for FAM155A Gene

miRTarBase miRNAs that target FAM155A

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM155A Gene

Localization for FAM155A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM155A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM155A gene
Compartment Confidence
plasma membrane 4
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (2)
  • Nucleus (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for FAM155A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM155A: view

Pathways & Interactions for FAM155A Gene

SuperPathways for FAM155A Gene

No Data Available

Interacting Proteins for FAM155A Gene

Gene Ontology (GO) - Biological Process for FAM155A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0098703 calcium ion import across plasma membrane IBA --
genes like me logo Genes that share ontologies with FAM155A: view

No data available for Pathways by source and SIGNOR curated interactions for FAM155A Gene

Drugs & Compounds for FAM155A Gene

No Compound Related Data Available

Transcripts for FAM155A Gene

mRNA/cDNA for FAM155A Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM155A Gene

Family with sequence similarity 155, member A:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM155A Gene

No ASD Table

Relevant External Links for FAM155A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM155A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM155A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM155A Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x6.2), Brain - Anterior cingulate cortex (BA24) (x5.7), Brain - Cortex (x4.7), Brain - Hypothalamus (x4.6), Brain - Hippocampus (x4.2), Brain - Amygdala (x4.2), and Pituitary (x4.1).

Protein differential expression in normal tissues from HIPED for FAM155A Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM155A Gene

Protein tissue co-expression partners for FAM155A Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of FAM155A Gene:


SOURCE GeneReport for Unigene cluster for FAM155A Gene:


Evidence on tissue expression from TISSUES for FAM155A Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with FAM155A: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM155A Gene

Orthologs for FAM155A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM155A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM155A 33 34
  • 99.64 (n)
(Canis familiaris)
Mammalia FAM155A 33 34
  • 91.99 (n)
(Rattus norvegicus)
Mammalia Fam155a 33
  • 88.3 (n)
(Mus musculus)
Mammalia Fam155a 33 16 34
  • 88.16 (n)
(Bos Taurus)
Mammalia FAM155A 33 34
  • 88.11 (n)
(Ornithorhynchus anatinus)
Mammalia FAM155A 34
  • 82 (a)
(Gallus gallus)
Aves -- 34
  • 81 (a)
-- 34
  • 81 (a)
FAM155A 33
  • 80.35 (n)
(Anolis carolinensis)
Reptilia FAM155A 34
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam155a 33
  • 73.08 (n)
(Danio rerio)
Actinopterygii fam155a 33 34
  • 67.51 (n)
FAM155A (2 of 2) 34
  • 56 (a)
Species where no ortholog for FAM155A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM155A Gene

Gene Tree for FAM155A (if available)
Gene Tree for FAM155A (if available)

Paralogs for FAM155A Gene

Paralogs for FAM155A Gene

genes like me logo Genes that share paralogs with FAM155A: view

Variants for FAM155A Gene

Sequence variations from dbSNP and Humsavar for FAM155A Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000001527 -- 107,548,205(-) A/C intron_variant
rs1000007907 -- 107,705,012(-) T/G intron_variant
rs1000014198 -- 107,376,208(-) C/A intron_variant
rs1000014873 -- 107,723,342(-) G/A intron_variant
rs1000020054 -- 107,315,854(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM155A Gene

Variant ID Type Subtype PubMed ID
nsv516705 CNV loss 19592680
nsv519927 CNV gain 19592680
nsv524956 CNV gain 19592680
nsv527392 CNV gain 19592680
nsv528262 CNV gain 19592680
nsv563012 CNV loss 21841781
nsv563013 CNV gain 21841781
nsv563014 CNV loss 21841781
nsv64265 CNV deletion 16902084
nsv510623 CNV deletion 20534489
nsv510364 OTHER sequence alteration 20534489
nsv477766 CNV novel sequence insertion 20440878
nsv475429 CNV novel sequence insertion 20440878
nsv456110 CNV gain 19166990
nsv1142159 CNV tandem duplication 24896259
nsv1122866 CNV deletion 24896259
nsv1113603 CNV deletion 24896259
nsv1113602 CNV deletion 24896259
nsv1070612 CNV deletion 25765185
nsv1054846 CNV gain 25217958
nsv1051067 CNV loss 25217958
nsv1050833 CNV gain 25217958
nsv1046112 CNV loss 25217958
nsv1042945 CNV loss 25217958
nsv1042814 CNV loss 25217958
nsv1039354 CNV loss 25217958
esv998714 CNV deletion 20482838
esv988148 CNV deletion 20482838
esv6504 CNV loss 19470904
esv3892444 CNV loss 25118596
esv3892443 CNV loss 25118596
esv3633493 CNV loss 21293372
esv3633490 CNV loss 21293372
esv3633488 CNV loss 21293372
esv3633486 CNV loss 21293372
esv3633485 CNV gain 21293372
esv3633483 CNV loss 21293372
esv3633482 CNV gain 21293372
esv3580880 CNV loss 25503493
esv3580879 CNV loss 25503493
esv3551048 CNV deletion 23714750
esv3551042 CNV deletion 23714750
esv3423936 CNV insertion 20981092
esv34169 CNV loss 18971310
esv34077 CNV loss 18971310
esv3387335 CNV insertion 20981092
esv3353494 CNV insertion 20981092
esv3347283 CNV insertion 20981092
esv2759965 CNV loss 17122850
esv2751127 CNV loss 17911159
esv2747971 CNV deletion 23290073
esv2747970 CNV deletion 23290073
esv2747969 CNV deletion 23290073
esv2747968 CNV deletion 23290073
esv2747967 CNV deletion 23290073
esv2747966 CNV deletion 23290073
esv2747965 CNV deletion 23290073
esv2747964 CNV deletion 23290073
esv2671096 CNV deletion 23128226
esv2667287 CNV deletion 23128226
esv2665818 CNV deletion 23128226
esv2658157 CNV deletion 23128226
esv2583398 CNV deletion 19546169
esv2481264 CNV deletion 19546169
esv2281615 CNV deletion 18987734
esv2242891 CNV deletion 18987734
esv2139400 CNV deletion 18987734
esv2069021 CNV deletion 18987734
esv1931581 CNV deletion 18987734
esv1148527 CNV deletion 17803354
dgv581e212 CNV loss 25503493
dgv1740n100 CNV loss 25217958
dgv1035n106 CNV deletion 24896259
nsv976150 CNV duplication 23825009
nsv958077 CNV deletion 24416366
nsv957464 CNV deletion 24416366
nsv951915 CNV deletion 24416366
nsv832715 CNV loss 17160897
nsv832713 CNV gain 17160897
nsv826781 CNV gain 20364138

Variation tolerance for FAM155A Gene

Residual Variation Intolerance Score: 32.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.47; 71.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM155A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM155A Gene

Disorders for FAM155A Gene

Additional Disease Information for FAM155A

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for FAM155A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM155A Gene

Publications for FAM155A Gene

  1. A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. (PMID: 21079607) Wang K … Price Foundation Collaborative Group (Molecular psychiatry 2011) 3 44 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  3. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney RJ … Gill M (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008) 3 44 58
  4. Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study. (PMID: 25208829) Anderson D … Blackwell JM (Genes and immunity 2014) 3 58
  5. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) Cross-Disorder Group of the Psychiatric Genomics Consortium (Lancet (London, England) 2013) 3 58

Products for FAM155A Gene

Sources for FAM155A Gene

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