Aliases for FAM120AOS Gene
Aliases for FAM120AOS Gene
External Ids for FAM120AOS Gene
- HGNC: 23389
- Entrez Gene: 158293
- Ensembl: ENSG00000188938
- UniProtKB: Q5T036
Previous HGNC Symbols for FAM120AOS Gene
- C9orf10OS
Previous GeneCards Identifiers for FAM120AOS Gene
- GC09M095242
- GC09M096208
- GC09M065886
Summaries for FAM120AOS Gene
-
Differences in the expression level of this gene are associated with the survival rate of those with glioma. [provided by RefSeq, May 2017]
GeneCards Summary for FAM120AOS Gene
FAM120AOS (Family With Sequence Similarity 120A Opposite Strand) is a Protein Coding gene.
Additional gene information for FAM120AOS Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM120AOS Gene
Genomics for FAM120AOS Gene
GeneHancer (GH) Regulatory Elements for FAM120AOS Gene
Promoters and enhancers for FAM120AOS Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around FAM120AOS on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the FAM120AOS gene promoter:
Regulatory Element Products
Genomic Locations for FAM120AOS Gene
Genomic Locations for FAM120AOS Gene
- chr9:93,443,332-93,453,592
- (GRCh38/hg38)
- Size:
- 10,261 bases
- Orientation:
- Minus strand
- chr9:96,208,776-96,215,874
- (GRCh37/hg19)
Genomic View for FAM120AOS Gene
Genes around FAM120AOS on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q22.31 by Ensembl
- 9q22.31 by Entrez Gene
- 9q22.31 by HGNC
FAM120AOS Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM120AOS Gene
Proteins for FAM120AOS Gene
-
Protein details for FAM120AOS Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5T036-F120S_HUMAN
- Recommended name:
- Uncharacterized protein FAM120AOS
- Protein Accession:
- Q5T036
- A6NN20
Protein attributes for FAM120AOS Gene
- Size:
- 256 amino acids
- Molecular mass:
- 27929 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM120AOS Gene
Post-translational modifications for FAM120AOS Gene
Other Protein References for FAM120AOS Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM120AOS
- Invitrogen Antibodies for FAM120AOS
- Search GeneTex for Antibodies for FAM120AOS
Protein Products
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- Search GeneTex for Proteins for FAM120AOS
Assay Products
No data available for DME Specific Peptides for FAM120AOS Gene
Domains & Families for FAM120AOS Gene
Gene Families for FAM120AOS Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for FAM120AOS Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM120AOS Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for FAM120AOS Gene
Function for FAM120AOS Gene
Phenotypes From GWAS Catalog for FAM120AOS Gene
Phenotypes for FAM120AOS Gene
- GenomeRNAi human phenotypes for FAM120AOS:
Animal Model Products
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-
-
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-
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CRISPR Products
-
OriGene CRISPR knockouts for FAM120AOS
- genomics-online: gRNA clones - Search results for available FAM120AOS gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM120AOS
- GenScript: Design CRISPR guide RNA sequences for FAM120AOS
miRNA for FAM120AOS Gene
- miRTarBase miRNAs that target FAM120AOS
-
- hsa-mir-192-5p (MIRT026475)
- hsa-mir-190a-3p (MIRT325473)
- hsa-mir-5011-5p (MIRT325475)
- hsa-mir-526b-5p (MIRT449319)
- hsa-mir-1273f (MIRT449320)
- hsa-mir-4708-5p (MIRT449321)
- hsa-mir-6088 (MIRT449322)
- hsa-mir-4770 (MIRT449323)
- hsa-mir-143-3p (MIRT449324)
- hsa-mir-5584-3p (MIRT449325)
- hsa-mir-148a-5p (MIRT449326)
- hsa-mir-548t-5p (MIRT449327)
- hsa-mir-548az-5p (MIRT449328)
- hsa-mir-548n (MIRT449329)
- hsa-mir-5010-3p (MIRT515084)
- hsa-mir-2113 (MIRT515085)
- hsa-mir-4775 (MIRT515086)
- hsa-mir-6832-5p (MIRT515087)
- hsa-mir-4524a-3p (MIRT515088)
- hsa-mir-4735-5p (MIRT515089)
- hsa-mir-4524b-3p (MIRT515090)
- hsa-mir-938 (MIRT550254)
- hsa-mir-129-2-3p (MIRT550255)
- hsa-mir-129-1-3p (MIRT550256)
- hsa-mir-6779-3p (MIRT550257)
- hsa-mir-4687-5p (MIRT550258)
- hsa-mir-3123 (MIRT550259)
- hsa-mir-888-5p (MIRT550260)
- hsa-mir-1277-5p (MIRT550261)
- hsa-mir-106a-3p (MIRT674212)
- hsa-mir-4284 (MIRT674213)
- hsa-mir-4634 (MIRT674214)
- hsa-mir-122-5p (MIRT674215)
- hsa-mir-504-3p (MIRT674216)
- hsa-mir-4772-3p (MIRT674217)
- hsa-mir-4638-5p (MIRT674218)
- hsa-mir-1307-3p (MIRT674219)
- hsa-mir-1304-3p (MIRT674220)
- hsa-mir-6741-3p (MIRT674221)
- hsa-mir-6890-3p (MIRT674222)
- hsa-mir-1306-5p (MIRT674223)
- hsa-mir-652-3p (MIRT674224)
- hsa-mir-454-3p (MIRT674225)
- hsa-mir-4295 (MIRT674226)
- hsa-mir-3666 (MIRT674227)
- hsa-mir-301b-3p (MIRT674228)
- hsa-mir-301a-3p (MIRT674229)
- hsa-mir-130b-3p (MIRT674230)
- hsa-mir-130a-3p (MIRT674231)
miRNA Products
- Search ViGene Biosciences for FAM120AOS
Inhibitory RNA Products
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Clone Products
-
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- VectorBuilder custom plasmid, inducible vectors for FAM120AOS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM120AOS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FAM120AOS gene related products
- orf clones - Search results for available FAM120AOS gene related products
- Applied Biological Materials Clones for FAM120AOS
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for FAM120AOS
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM120AOS gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM120AOS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM120AOS gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM120AOS Gene
Localization for FAM120AOS Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM120AOS Gene
Pathways & Interactions for FAM120AOS Gene
No data available for Pathways by source and SIGNOR curated interactions for FAM120AOS Gene
Transcripts for FAM120AOS Gene
mRNA/cDNA for FAM120AOS Gene
- (2) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (277) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM120AOS Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM120AOS
- genomics-online: gRNA clones - Search results for available FAM120AOS gene related products
- Applied Biological Materials CRISPR for FAM120AOS
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM120AOS
- GenScript: Design CRISPR guide RNA sequences for FAM120AOS
miRNA Products
- Search ViGene Biosciences for FAM120AOS
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FAM120AOS
- Browse OriGene Inhibitory RNA Products For FAM120AOS
- genomics-online: shRNA clones - Search results for available FAM120AOS gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM120AOS gene
Clone Products
-
OriGene ORF clones in human for FAM120AOS
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for FAM120AOS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM120AOS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FAM120AOS gene related products
- orf clones - Search results for available FAM120AOS gene related products
- Applied Biological Materials Clones for FAM120AOS
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f |
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| SP8: |
Expression for FAM120AOS Gene
This gene is overexpressed in Adipocyte (62.1) and Bone marrow mesenchymal stem cell (6.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM120AOS Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM120AOS Gene:
FAM120AOSSOURCE GeneReport for Unigene cluster for FAM120AOS Gene:
Hs.350364Evidence on tissue expression from TISSUES for FAM120AOS Gene
- Nervous system(2.8)
- Lung(2.5)
Primer Products
-
OriGene qPCR primer pairs and template standards for FAM120AOS
-
OriGene qPCR primer pairs for FAM120AOS
- genomics-online: primer clones - Search results for available FAM120AOS gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM120AOS Gene
Orthologs for FAM120AOS Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM120AOS 33 34 |
|
- Species where no ortholog for FAM120AOS was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM120AOS Gene
No data available for Paralogs for FAM120AOS Gene
Variants for FAM120AOS Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs140119177 | likely-pathogenic, Bilateral undescended testicles, Chronic lung disease, Coarse facial features, Cutis laxa, Gastroesophageal reflux, Hyperactive airways, Muscular hypotonia, Pectus excavatum, Scoliosis | 93,447,639(-) | G/A | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000363955 | -- | 93,451,649(-) | G/C | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000533616 | -- | 93,452,790(-) | A/G | 5_prime_UTR_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, upstream_transcript_variant | |
| rs1000625591 | -- | 93,446,110(-) | A/C | downstream_transcript_variant | |
| rs1000967783 | -- | 93,453,190(-) | G/A | 5_prime_UTR_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2672054 | CNV | deletion | 23128226 |
| esv2738783 | CNV | deletion | 23290073 |
| esv2738785 | CNV | deletion | 23290073 |
| esv3621099 | CNV | loss | 21293372 |
| nsv1075663 | CNV | deletion | 25765185 |
| nsv1124450 | CNV | deletion | 24896259 |
| nsv950899 | CNV | duplication | 24416366 |
Residual Variation Intolerance Score:
74.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.96;
74.67% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FAM120AOS Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM120AOS Gene
Disorders for FAM120AOS Gene
Additional Disease Information for FAM120AOS
No disorders were found for FAM120AOS Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM120AOS Gene
Publications for FAM120AOS Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. (PMID: 14585507) Holden S … Raymond FL (Gene 2003) 2 3 58
- Independent validation of a mathematical genomic model for survival of glioma patients. (PMID: 27429853) Nikas JB (American journal of cancer research 2016) 3 58
- A genome-wide association study of body mass index across early life and childhood. (PMID: 25953783) Warrington NM … Palmer LJ (International journal of epidemiology 2015) 3 58
- Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families. (PMID: 25558065) Alazami AM … Alkuraya FS (Cell reports 2015) 3 58
Products for FAM120AOS Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM120AOS
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM120AOS
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available FAM120AOS related products ranked by validation data
- antibodies-online: Search results for available FAM120AOS related products ranked by validation data
- antibodies-online: Search results for available FAM120AOS related products ranked by validation data
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- ViGene Biosciences adenoviral particle packaged cDNA for FAM120AOS gene
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Sources for FAM120AOS Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
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