Aliases for FAM110D Gene

Aliases for FAM110D Gene

  • Family With Sequence Similarity 110 Member D 2 3 5
  • Protein FAM110D 3 4
  • GRRP1 3 4
  • Family With Sequence Similarity 110, Member D 2
  • Glycine/Arginine Rich Protein 1 2
  • Glycine/Arginine-Rich Protein 1 3
  • FLJ14050 2
  • FAM110D 5

External Ids for FAM110D Gene

Previous HGNC Symbols for FAM110D Gene

  • GRRP1

Previous GeneCards Identifiers for FAM110D Gene

  • GC01P026486

Summaries for FAM110D Gene

GeneCards Summary for FAM110D Gene

FAM110D (Family With Sequence Similarity 110 Member D) is a Protein Coding gene. An important paralog of this gene is FAM110C.

Additional gene information for FAM110D Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FAM110D Gene

Genomics for FAM110D Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FAM110D Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM110D on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FAM110D

Genomic Locations for FAM110D Gene

Genomic Locations for FAM110D Gene
chr1:26,159,079-26,163,962
(GRCh38/hg38)
Size:
4,884 bases
Orientation:
Plus strand
chr1:26,485,511-26,489,119
(GRCh37/hg19)
Size:
3,609 bases
Orientation:
Plus strand

Genomic View for FAM110D Gene

Genes around FAM110D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM110D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM110D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM110D Gene

Proteins for FAM110D Gene

  • Protein details for FAM110D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TAY7-F110D_HUMAN
    Recommended name:
    Protein FAM110D
    Protein Accession:
    Q8TAY7
    Secondary Accessions:
    • A8K3V0
    • Q9H7Z4

    Protein attributes for FAM110D Gene

    Size:
    271 amino acids
    Molecular mass:
    28710 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14829.1; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for FAM110D Gene

Post-translational modifications for FAM110D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM110D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM110D Gene

Domains & Families for FAM110D Gene

Gene Families for FAM110D Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM110D Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM110D Gene

GenScript: Design optimal peptide antigens:
  • Glycine/arginine-rich protein 1 (GRPP1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8TAY7

UniProtKB/Swiss-Prot:

F110D_HUMAN :
  • Belongs to the FAM110 family.
Family:
  • Belongs to the FAM110 family.
genes like me logo Genes that share domains with FAM110D: view

Function for FAM110D Gene

Phenotypes From GWAS Catalog for FAM110D Gene

genes like me logo Genes that share phenotypes with FAM110D: view

Animal Model Products

CRISPR Products

miRNA for FAM110D Gene

miRTarBase miRNAs that target FAM110D

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM110D

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM110D Gene

Localization for FAM110D Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM110D gene
Compartment Confidence
nucleus 2
extracellular 0
mitochondrion 0
cytosol 0

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM110D Gene

Pathways & Interactions for FAM110D Gene

PathCards logo

SuperPathways for FAM110D Gene

No Data Available

Interacting Proteins for FAM110D Gene

Gene Ontology (GO) - Biological Process for FAM110D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM110D Gene

Drugs & Compounds for FAM110D Gene

No Compound Related Data Available

Transcripts for FAM110D Gene

mRNA/cDNA for FAM110D Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FAM110D

Alternative Splicing Database (ASD) splice patterns (SP) for FAM110D Gene

No ASD Table

Relevant External Links for FAM110D Gene

GeneLoc Exon Structure for
FAM110D

Expression for FAM110D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM110D Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM110D Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x4.5).

Protein differential expression in normal tissues from HIPED for FAM110D Gene

This gene is overexpressed in Serum (54.5) and Plasma (14.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM110D Gene



Protein tissue co-expression partners for FAM110D Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FAM110D

SOURCE GeneReport for Unigene cluster for FAM110D Gene:

Hs.694119
genes like me logo Genes that share expression patterns with FAM110D: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM110D Gene

Orthologs for FAM110D Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM110D Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia FAM110D 30 31
  • 99.38 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia FAM110D 30 31
  • 89.91 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia FAM110D 30 31
  • 89.14 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Grrp1 30 17 31
  • 86.47 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Fam110d 30
  • 85.12 (n)
Chicken
(Gallus gallus)
Aves FAM110D 30 31
  • 59.51 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia FAM110D 31
  • 45 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii si:ch211-107n13.1 30
  • 53.86 (n)
FAM110D 31
  • 22 (a)
OneToOne
Species where no ortholog for FAM110D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for FAM110D Gene

ENSEMBL:
Gene Tree for FAM110D (if available)
TreeFam:
Gene Tree for FAM110D (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FAM110D: view image

Paralogs for FAM110D Gene

Paralogs for FAM110D Gene

genes like me logo Genes that share paralogs with FAM110D: view

Variants for FAM110D Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FAM110D Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
rs3748856 - p.His53Arg

Additional dbSNP identifiers (rs#s) for FAM110D Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM110D Gene

Variant ID Type Subtype PubMed ID
nsv1002191 CNV gain 25217958

Variation tolerance for FAM110D Gene

Gene Damage Index Score: 6.81; 79.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM110D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM110D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM110D Gene

Disorders for FAM110D Gene

No disorders were found for FAM110D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM110D Gene

Publications for FAM110D Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for FAM110D Gene

Sources for FAM110D Gene