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Aliases for FAM106A Gene

Aliases for FAM106A Gene

  • Family With Sequence Similarity 106 Member A 2 3
  • Family With Sequence Similarity 106, Member A 2
  • Protein FAM106A 3

External Ids for FAM106A Gene

Previous GeneCards Identifiers for FAM106A Gene

  • GC17M018369
  • GC17M018428
  • GC17M018429
  • GC17M018474
  • GC17M018575
  • GC17M018642
  • GC17M018677
  • GC17M018717
  • GC17M018756
  • GC17M018801
  • GC17M018845
  • GC17M018890

Summaries for FAM106A Gene

GeneCards Summary for FAM106A Gene

FAM106A (Family With Sequence Similarity 106 Member A) is a Protein Coding gene.

Additional gene information for FAM106A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM106A Gene

Genomics for FAM106A Gene

GeneHancer (GH) Regulatory Elements for FAM106A Gene

Promoters and enhancers for FAM106A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J018313 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 8.1 +211.1 211096 5.2 HDGF PKNOX1 CLOCK ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 E2F8 SMCR8 TOP3A DRG2 FLII SHMT1 FOXO3B ENSG00000262202 ENSG00000264885 TVP23B CCDC144B
GH17J018256 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 7.8 +267.3 267320 6.3 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF207 MIEF2 FLII SHMT1 LLGL1 SMCR8 FOXO3B ENSG00000264885 ENSG00000262202 DRG2 MYO15A
GH17J018410 Promoter/Enhancer 1.6 Ensembl ENCODE dbSUPER 5.2 +115.0 115045 2.8 SIN3A GLI4 ZNF2 YY1 KLF7 KLF13 SP3 YY2 REST TSHZ1 LINC02076 MAPK7 FOXO3B DRG2 SMCR8 SMCR5 SHMT1 ENSG00000264885 ZNF286B ENSG00000262202
GH17J018318 Enhancer 0.8 ENCODE dbSUPER 8.1 +206.7 206735 2.5 MEIS2 CTCF ZNF654 REST ZNF48 RAD21 ZNF121 ZSCAN21 ZNF444 ZBTB17 SHMT1 MIEF2 FAM106A PIR48556 SMCR8
GH17J017569 Enhancer 1.1 ENCODE dbSUPER 4.5 +955.5 955465 2.8 FOXA2 MLX ARID4B DMAP1 ZNF48 ETS1 YY1 RXRA REST ZNF623 PEMT FAM106A GC17P017579 EEF1A1P43
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FAM106A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the FAM106A gene promoter:
  • PPAR-gamma2
  • PPAR-gamma1
  • FOXO1a
  • FOXO1
  • ITF-2
  • Tal-1beta
  • GATA-1
  • LCR-F1
  • POU3F1
  • c-Myc

Genomic Locations for FAM106A Gene

Genomic Locations for FAM106A Gene
chr17:18,524,566-18,526,846
(GRCh38/hg38)
Size:
2,281 bases
Orientation:
Minus strand
chr17:18,427,880-18,430,160
(GRCh37/hg19)
Size:
2,281 bases
Orientation:
Minus strand

Genomic View for FAM106A Gene

Genes around FAM106A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM106A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM106A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM106A Gene

Proteins for FAM106A Gene

  • Protein details for FAM106A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4KMX7-F106A_HUMAN
    Recommended name:
    Protein FAM106A
    Protein Accession:
    Q4KMX7
    Secondary Accessions:
    • Q9HAD1

    Protein attributes for FAM106A Gene

    Size:
    169 amino acids
    Molecular mass:
    18795 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM106A Gene

Post-translational modifications for FAM106A Gene

No Post-translational modifications

Other Protein References for FAM106A Gene

REFSEQ proteins:

No data available for DME Specific Peptides for FAM106A Gene

Domains & Families for FAM106A Gene

Gene Families for FAM106A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM106A Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM106A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4KMX7

UniProtKB/Swiss-Prot:

F106A_HUMAN :
  • Belongs to the FAM106 family.
Family:
  • Belongs to the FAM106 family.
genes like me logo Genes that share domains with FAM106A: view

Function for FAM106A Gene

genes like me logo Genes that share phenotypes with FAM106A: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM106A Gene

Localization for FAM106A Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM106A Gene

Pathways & Interactions for FAM106A Gene

SuperPathways for FAM106A Gene

No Data Available

Interacting Proteins for FAM106A Gene

Gene Ontology (GO) - Biological Process for FAM106A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM106A Gene

Drugs & Compounds for FAM106A Gene

No Compound Related Data Available

Transcripts for FAM106A Gene

mRNA/cDNA for FAM106A Gene

Unigene Clusters for FAM106A Gene

Family with sequence similarity 106, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM106A Gene

No ASD Table

Relevant External Links for FAM106A Gene

GeneLoc Exon Structure for
FAM106A
ECgene alternative splicing isoforms for
FAM106A

Expression for FAM106A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM106A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM106A Gene:

FAM106A

SOURCE GeneReport for Unigene cluster for FAM106A Gene:

Hs.674403
genes like me logo Genes that share expression patterns with FAM106A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM106A Gene

Orthologs for FAM106A Gene

No data available for Orthologs and Evolution for FAM106A Gene

Paralogs for FAM106A Gene

(2) SIMAP similar genes for FAM106A Gene using alignment to 1 proteins:

  • F106A_HUMAN
genes like me logo Genes that share paralogs with FAM106A: view

No data available for Paralogs for FAM106A Gene

Variants for FAM106A Gene

Sequence variations from dbSNP and Humsavar for FAM106A Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1002600646 -- 18,526,896(-) T/G upstream_transcript_variant
rs1002647908 -- 18,527,663(-) T/G upstream_transcript_variant
rs1004460114 -- 18,524,527(-) CA/ downstream_transcript_variant
rs1010943053 -- 18,526,943(-) TTTATTTTAT/TTTAT upstream_transcript_variant
rs1015003274 -- 18,527,977(-) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM106A Gene

Variant ID Type Subtype PubMed ID
dgv27e213 CNV loss 24956385
dgv3110n100 CNV gain 25217958
dgv3111n100 CNV gain 25217958
dgv3112n100 CNV gain+loss 25217958
dgv3113n100 CNV loss 25217958
dgv3114n100 CNV gain+loss 25217958
dgv3115n100 CNV gain 25217958
dgv5489n54 CNV loss 21841781
dgv55e203 CNV gain+loss 21179565
esv2670394 CNV deletion 23128226
esv2758677 CNV gain+loss 17122850
esv3640153 CNV loss 21293372
nsv1121932 CNV deletion 24896259
nsv1144794 CNV deletion 24896259
nsv1160460 OTHER complex 26073780
nsv1160461 CNV deletion 26073780
nsv428333 CNV gain 18775914
nsv442738 CNV gain+loss 18776908
nsv469661 CNV gain 16826518
nsv511052 OTHER complex 20534489
nsv511593 CNV loss 21212237
nsv827913 CNV gain 20364138
nsv833388 CNV loss 17160897
nsv9504 CNV gain+loss 18304495
nsv953840 CNV deletion 24416366
nsv962275 CNV duplication 23825009

Variation tolerance for FAM106A Gene

Gene Damage Index Score: 0.06; 1.45% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM106A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM106A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM106A Gene

Disorders for FAM106A Gene

Additional Disease Information for FAM106A

No disorders were found for FAM106A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM106A Gene

Publications for FAM106A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4 58
  2. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 58
  4. Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs. (PMID: 11997339) Park SS … Lupski JR (Genome research 2002) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for FAM106A Gene

Sources for FAM106A Gene

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