Aliases for FALEC Gene

Subcategory (RNA class) for FALEC Gene

lncRNA

Quality Score for this RNA gene is

15

Aliases for FALEC Gene

  • Focally Amplified Long Non-Coding RNA In Epithelial Cancer 2 3 5
  • Long Intergenic Non-Protein Coding RNA 568 2 3
  • Focally Amplified LncRNA On Chromosome 1 2 3
  • FALEC 2 170
  • Noncoding RNA-Activating 1 3
  • NONHSAG002854 94
  • HSALNG0007045 169
  • LINC00568 3
  • NcRNA-A1 3
  • FAL1 3

External Ids for FALEC Gene

Previous HGNC Symbols for FALEC Gene

  • LINC00568

Summaries for FALEC Gene

GeneCards Summary for FALEC Gene

FALEC (Focally Amplified Long Non-Coding RNA In Epithelial Cancer) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with FALEC include Thyroid Gland Cancer and Prostate Cancer.

Additional gene information for FALEC Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FALEC Gene

Genomics for FALEC Gene

GeneHancer (GH) Regulatory Elements for FALEC Gene

Promoters and enhancers for FALEC Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FALEC on UCSC Golden Path with GeneCards custom track

Genomic Locations for FALEC Gene

Genomic Locations for FALEC Gene
chr1:150,514,953-150,522,860
(GRCh38/hg38)
Size:
7,908 bases
Orientation:
Plus strand
chr1:150,488,233-150,490,508
(GRCh37/hg19)
Size:
2,276 bases
Orientation:
Plus strand

Genomic View for FALEC Gene

Genes around FALEC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FALEC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FALEC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FALEC Gene

Proteins for FALEC Gene

No data available for DME Specific Peptides for FALEC Gene

Domains & Families for FALEC Gene

Gene Families for FALEC Gene

genes like me logo Genes that share domains with FALEC: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FALEC Gene

Function for FALEC Gene

Phenotypes From GWAS Catalog for FALEC Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FALEC Gene

Localization for FALEC Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FALEC Gene

Pathways & Interactions for FALEC Gene

PathCards logo

SuperPathways for FALEC Gene

No Data Available

Gene Ontology (GO) - Biological Process for FALEC Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FALEC Gene

Drugs & Compounds for FALEC Gene

No Compound Related Data Available

Transcripts for FALEC Gene

mRNA/cDNA for FALEC Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(5) RNACentral transcripts :
(4) LNCipedia transcripts :
(5) LncBook transcripts :
(3) NONCODE transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for FALEC Gene

No ASD Table

Relevant External Links for FALEC Gene

GeneLoc Exon Structure for
FALEC
ECgene alternative splicing isoforms for
FALEC

Expression for FALEC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FALEC Gene

NURSA nuclear receptor signaling pathways regulating expression of FALEC Gene:

FALEC
genes like me logo Genes that share expression patterns with FALEC: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FALEC Gene

Orthologs for FALEC Gene

Evolution for FALEC Gene

ENSEMBL:
Gene Tree for FALEC (if available)
TreeFam:
Gene Tree for FALEC (if available)

No data available for Orthologs for FALEC Gene

Paralogs for FALEC Gene

No data available for Paralogs for FALEC Gene

Variants for FALEC Gene

Sequence variations from dbSNP and Humsavar for FALEC Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000305569 -- 150,513,999(+) T/C upstream_transcript_variant
rs1001413640 -- 150,513,930(+) C/T upstream_transcript_variant
rs1002262938 -- 150,515,294(+) G/A upstream_transcript_variant
rs1002731675 -- 150,518,233(+) T/C downstream_transcript_variant
rs1003097542 -- 150,518,465(+) A/G/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for FALEC Gene

Variant ID Type Subtype PubMed ID
nsv1006838 CNV gain 25217958

Additional Variant Information for FALEC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FALEC

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FALEC Gene

Disorders for FALEC Gene

MalaCards: The human disease database

(3) MalaCards diseases for FALEC Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
thyroid gland cancer
  • malignant neoplasm of thyroid gland
prostate cancer
  • prostate cancer, somatic
hepatocellular carcinoma
  • hcc
- elite association - COSMIC cancer census association via MalaCards
Search FALEC in MalaCards View complete list of genes associated with diseases

Additional Disease Information for FALEC

genes like me logo Genes that share disorders with FALEC: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FALEC Gene

Publications for FALEC Gene

  1. Up-regulation of long noncoding RNA FALEC predicts poor prognosis and promotes melanoma cell proliferation through epigenetically silencing p21. (PMID: 29196104) Ni N … Sun J (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017) 2 3 56
  2. A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. (PMID: 25203321) Hu X … Zhang L (Cancer cell 2014) 2 3 56
  3. Long noncoding RNAs with enhancer-like function in human cells. (PMID: 20887892) Ørom UA … Shiekhattar R (Cell 2010) 2 3 56
  4. LncRNA FAL1 promotes carcinogenesis by regulation of miR-637/NUPR1 pathway in colorectal cancer. (PMID: 30267804) Wang L … Zhang B (The international journal of biochemistry & cell biology 2019) 3 56
  5. Long noncoding RNA FAL1 promotes proliferation and inhibits apoptosis of human colon cancer cells. (PMID: 30290064) Wu K … Zhang J (IUBMB life 2018) 3 56

Products for FALEC Gene

Sources for FALEC Gene