Aliases for FABP7 Gene
External Ids for FABP7 Gene
Previous GeneCards Identifiers for FABP7 Gene
The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]
GeneCards Summary for FABP7 Gene
FABP7 (Fatty Acid Binding Protein 7) is a Protein Coding gene. Diseases associated with FABP7 include Optic Nerve Glioma and Malignant Glioma. Among its related pathways are Lipoprotein metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include transporter activity and lipid binding. An important paralog of this gene is FABP3.
UniProtKB/Swiss-Prot for FABP7 Gene
B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).