Aliases for FABP3 Gene
External Ids for FABP3 Gene
Previous HGNC Symbols for FABP3 Gene
Previous GeneCards Identifiers for FABP3 Gene
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
GeneCards Summary for FABP3 Gene
FABP3 (Fatty Acid Binding Protein 3) is a Protein Coding gene. Diseases associated with FABP3 include Pulmonary Embolism and Acute Myocardial Infarction. Among its related pathways are Mesenchymal Stem Cells and Lineage-specific Markers and Glucose / Energy Metabolism. Gene Ontology (GO) annotations related to this gene include transporter activity and cytoskeletal protein binding. An important paralog of this gene is FABP4.
UniProtKB/Swiss-Prot Summary for FABP3 Gene
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.