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Aliases for F5 Gene

Aliases for F5 Gene

  • Coagulation Factor V 2 3 3 5
  • Coagulation Factor V (Proaccelerin, Labile Factor) 2 3
  • Activated Protein C Cofactor 3 4
  • Coagulation Factor V Jinjiang A2 Domain 3
  • Proaccelerin, Labile Factor 4
  • Factor V Leiden 3
  • RPRGL1 3
  • THPH2 3
  • PCCF 3
  • FVL 3

External Ids for F5 Gene

Previous GeneCards Identifiers for F5 Gene

  • GC01M167112
  • GC01M165134
  • GC01M166179
  • GC01M166670
  • GC01M166215
  • GC01M167750
  • GC01M140703

Summaries for F5 Gene

Entrez Gene Summary for F5 Gene

  • This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]

GeneCards Summary for F5 Gene

F5 (Coagulation Factor V) is a Protein Coding gene. Diseases associated with F5 include Factor V Deficiency and Thrombophilia Due To Activated Protein C Resistance. Among its related pathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and copper ion binding. An important paralog of this gene is F8.

UniProtKB/Swiss-Prot for F5 Gene

  • Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.

Gene Wiki entry for F5 Gene

PharmGKB "VIP" Summary for F5 Gene

Additional gene information for F5 Gene

No data available for CIViC summary , Tocris Summary , fRNAdb sequence ontologies and piRNA Summary for F5 Gene

Genomics for F5 Gene

GeneHancer (GH) Regulatory Elements for F5 Gene

Promoters and enhancers for F5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J169584 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 656 +0.8 787 2.4 HDGF FOXA2 ARID4B DMAP1 ZNF2 ZNF48 YY1 SLC30A9 GLIS2 ZNF143 F5 SCYL3 BLZF1 SLC19A2 GC01P169565
GH01J169688 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 11.5 -110.4 -110408 17.4 CTCF PKNOX1 EBF1 BATF RAD21 GATA3 ZNF316 EED ATF7 ETV6 METTL18 C1orf112 SELP F5 SELL SCYL3 KIFAP3 ENSG00000230704 METTL11B GC01M169692
GH01J169571 Enhancer 1 FANTOM5 ENCODE 11.1 +14.3 14255 1.6 ELF3 FOXA2 RARA THAP11 MIXL1 RXRA PPARG KAT8 SSRP1 MIER3 F5 C1orf112 METTL18 SELE SCYL3 GC01P169565
GH01J169779 Enhancer 0.9 Ensembl ENCODE 10.8 -194.3 -194254 3.6 PKNOX1 NEUROD1 ZKSCAN1 FOSL1 CTBP1 GATA3 POLR2A NFE2 FOSL2 RCOR1 METTL18 F5 CCDC181 SCYL3 LOC101928628 C1orf112
GH01J169547 Enhancer 0.7 ENCODE 11.3 +40.0 40020 0.2 CTCF ZNF2 RAD21 RFX5 YY1 CC2D1A GATA3 ARID2 SCRT2 ZNF143 ENSG00000213062 SLC19A2 F5 CCDC181 SELE GC01P169565 GC01P169489
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around F5 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the F5 gene promoter:

Genomic Locations for F5 Gene

Genomic Locations for F5 Gene
chr1:169,511,954-169,586,588
(GRCh38/hg38)
Size:
74,635 bases
Orientation:
Minus strand
chr1:169,481,192-169,555,826
(GRCh37/hg19)

Genomic View for F5 Gene

Genes around F5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
F5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for F5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for F5 Gene

Proteins for F5 Gene

  • Protein details for F5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P12259-FA5_HUMAN
    Recommended name:
    Coagulation factor V
    Protein Accession:
    P12259
    Secondary Accessions:
    • A8K6E8
    • Q14285
    • Q2EHR5
    • Q5R346
    • Q5R347
    • Q6UPU6
    • Q8WWQ6

    Protein attributes for F5 Gene

    Size:
    2224 amino acids
    Molecular mass:
    251703 Da
    Quaternary structure:
    • Factor Va, the activated form of factor V, is composed of a heavy chain and a light chain, non-covalently bound. The interaction between the two chains is calcium-dependent. Forms heterodimer with SERPINA5.
    SequenceCaution:
    • Sequence=ABD23003.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI23065.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for F5 Gene

neXtProt entry for F5 Gene

Post-translational modifications for F5 Gene

  • Thrombin activates factor V proteolytically to the active cofactor, factor Va (formation of a heavy chain at the N-terminus and a light chain at the C-terminus).
  • Sulfation is required for efficient thrombin cleavage and activation and for full procoagulant activity.
  • Activated protein C inactivates factor V and factor Va by proteolytic degradation.
  • Phosphorylated by FAM20C in the extracellular medium.
  • Glycosylation at Asn2209, isoforms=2010, isoforms=1703, Asn1559, isoforms=1499, isoforms=1479, isoforms=1106, isoforms=1103, Asn1083, isoforms=1074, Asn977, isoforms=938, isoforms=821, isoforms=805, isoforms=804, isoforms=782, Asn776, Asn760, isoforms=752, isoforms=741, isoforms=554, isoforms=468, isoforms=460, isoforms=382, Asn297, isoforms=239, Asn55, and Asn51
  • Modification sites at PhosphoSitePlus

Other Protein References for F5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for F5 Gene

Domains & Families for F5 Gene

Gene Families for F5 Gene

Human Protein Atlas (HPA):
  • Candidate cardiovascular disease genes
  • Disease related genes
  • FDA approved drug targets
  • Plasma proteins
  • Predicted secreted proteins

Graphical View of Domain Structure for InterPro Entry

P12259

UniProtKB/Swiss-Prot:

FA5_HUMAN :
  • Domain B contains 35 x 9 AA tandem repeats, and 2 x 17 AA repeats.
  • Belongs to the multicopper oxidase family.
Domain:
  • Domain B contains 35 x 9 AA tandem repeats, and 2 x 17 AA repeats.
Family:
  • Belongs to the multicopper oxidase family.
genes like me logo Genes that share domains with F5: view

Function for F5 Gene

Molecular function for F5 Gene

UniProtKB/Swiss-Prot Function:
Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
UniProtKB/Swiss-Prot EnzymeRegulation:
Inhibited by SERPINA5.
GENATLAS Biochemistry:
coagulation factor V (proaccelerin,labile factor),cofactor in the activation of prothrombin (F2) by activated F10,colocalized and complexed with merin multimerin in platelets alpha-granules

Phenotypes From GWAS Catalog for F5 Gene

Gene Ontology (GO) - Molecular Function for F5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005507 copper ion binding IEA --
GO:0005515 protein binding IPI 2844223
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with F5: view
genes like me logo Genes that share phenotypes with F5: view

Human Phenotype Ontology for F5 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for F5 Gene

MGI Knock Outs for F5:
  • F5 F5<tm1Dgi>

miRNA for F5 Gene

Clone Products

  • Addgene plasmids for F5

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for F5 Gene

Localization for F5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for F5 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for F5 gene
Compartment Confidence
extracellular 5
plasma membrane 4
endoplasmic reticulum 4
golgi apparatus 2
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for F5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IEA --
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0005886 plasma membrane TAS --
genes like me logo Genes that share ontologies with F5: view

Pathways & Interactions for F5 Gene

genes like me logo Genes that share pathways with F5: view

Gene Ontology (GO) - Biological Process for F5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002576 platelet degranulation TAS --
GO:0006888 ER to Golgi vesicle-mediated transport TAS --
GO:0007596 blood coagulation TAS --
GO:0007599 hemostasis IEA --
GO:0008015 blood circulation IEA --
genes like me logo Genes that share ontologies with F5: view

No data available for SIGNOR curated interactions for F5 Gene

Drugs & Compounds for F5 Gene

(93) Drugs for F5 Gene - From: DrugBank, PharmGKB, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Copper Approved, Investigational Pharma Carrier, binder 202
Drotrecogin alfa Approved, Investigational, Withdrawn Pharma inhibitor, Target, multitarget 0
Thrombin Approved, Investigational Pharma Target, activator 332
Tamoxifen Approved Pharma Antagonist TGF-β modulatory and PKC inhibitory effects, ER antagonist, Anti-Estrogens 408
calcium Approved Nutra 0

(54) Additional Compounds for F5 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with F5: view

Transcripts for F5 Gene

mRNA/cDNA for F5 Gene

Unigene Clusters for F5 Gene

Coagulation factor V (proaccelerin, labile factor):
Representative Sequences:

Clone Products

  • Addgene plasmids for F5

Alternative Splicing Database (ASD) splice patterns (SP) for F5 Gene

No ASD Table

Relevant External Links for F5 Gene

GeneLoc Exon Structure for
F5
ECgene alternative splicing isoforms for
F5

Expression for F5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for F5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for F5 Gene

This gene is overexpressed in Liver (x24.7) and Whole Blood (x15.1).

Protein differential expression in normal tissues from HIPED for F5 Gene

This gene is overexpressed in Serum (26.8), Peripheral blood mononuclear cells (18.1), Plasma (10.3), and Platelet (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for F5 Gene



NURSA nuclear receptor signaling pathways regulating expression of F5 Gene:

F5

SOURCE GeneReport for Unigene cluster for F5 Gene:

Hs.30054

mRNA Expression by UniProt/SwissProt for F5 Gene:

P12259-FA5_HUMAN
Tissue specificity: Plasma.

Evidence on tissue expression from TISSUES for F5 Gene

  • Blood(4.8)
  • Bone marrow(4.1)
  • Liver(3)
  • Lung(2.4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for F5 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • urinary
Regions:
Head and neck:
  • brain
  • ear
  • face
  • head
  • mouth
  • nose
  • salivary gland
Thorax:
  • breast
  • esophagus
  • heart
  • lung
Abdomen:
  • abdominal wall
  • intestine
  • kidney
  • liver
  • small intestine
  • spleen
  • stomach
Pelvis:
  • testicle
  • uterus
Limb:
  • digit
  • finger
  • foot
  • hand
  • lower limb
  • nail
  • toe
  • upper limb
General:
  • blood
  • blood vessel
  • coagulation system
  • red blood cell
  • skin
genes like me logo Genes that share expression patterns with F5: view

No data available for Protein tissue co-expression partners for F5 Gene

Orthologs for F5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for F5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia F5 34 33
  • 95.69 (n)
OneToOne
dog
(Canis familiaris)
Mammalia F5 34 33
  • 85.12 (n)
OneToOne
cow
(Bos Taurus)
Mammalia F5 34 33
  • 83.11 (n)
OneToOne
mouse
(Mus musculus)
Mammalia F5 16 34 33
  • 78.53 (n)
rat
(Rattus norvegicus)
Mammalia F5 33
  • 74.49 (n)
oppossum
(Monodelphis domestica)
Mammalia F5 34
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia F5 34
  • 55 (a)
OneToOne
chicken
(Gallus gallus)
Aves F5 34 33
  • 63.68 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia F5 34
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia f5 33
  • 61.19 (n)
zebrafish
(Danio rerio)
Actinopterygii f5 34 33
  • 56.94 (n)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2640 34
  • 33 (a)
OneToMany
Species where no ortholog for F5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for F5 Gene

ENSEMBL:
Gene Tree for F5 (if available)
TreeFam:
Gene Tree for F5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for F5: view image

Paralogs for F5 Gene

Paralogs for F5 Gene

(9) SIMAP similar genes for F5 Gene using alignment to 6 proteins:

  • FA5_HUMAN
  • B4DU26_HUMAN
  • C8C1T0_HUMAN
  • C8C1T1_HUMAN
  • Q15430_HUMAN
  • Q8IUL1_HUMAN
genes like me logo Genes that share paralogs with F5: view

Variants for F5 Gene

Sequence variations from dbSNP and Humsavar for F5 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1026400103 uncertain-significance, Budd-Chiari syndrome, Thrombophilia due to activated protein C resistance, Factor V deficiency, Thrombophilia 169,536,518(-) A/T coding_sequence_variant, missense_variant
rs1046712 benign, likely-benign, not specified, Budd-Chiari syndrome, Factor V deficiency, Thrombophilia due to activated protein C resistance, Thrombophilia 169,541,237(-) G/T coding_sequence_variant, missense_variant
rs112333778 uncertain-significance, Factor V deficiency, Thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Thrombophilia 169,544,486(-) C/T coding_sequence_variant, synonymous_variant
rs115148599 uncertain-significance, Thrombophilia, Factor V deficiency, Thrombophilia due to activated protein C resistance, Budd-Chiari syndrome 169,540,781(-) T/A coding_sequence_variant, missense_variant
rs115882472 uncertain-significance, Thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Factor V deficiency, Thrombophilia 169,513,950(-) A/C 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for F5 Gene

Variant ID Type Subtype PubMed ID
dgv221n106 CNV tandem duplication 24896259
esv22143 CNV gain+loss 19812545
esv2518089 CNV insertion 19546169
esv3306273 CNV mobile element insertion 20981092
esv3308424 CNV mobile element insertion 20981092
esv3425707 CNV insertion 20981092
nsv1078878 OTHER inversion 25765185
nsv548187 CNV loss 21841781
nsv831871 CNV loss 17160897

Variation tolerance for F5 Gene

Residual Variation Intolerance Score: 95% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 18.62; 98.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for F5 Gene

Human Gene Mutation Database (HGMD)
F5
SNPedia medical, phenotypic, and genealogical associations of SNPs for
F5

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for F5 Gene

Disorders for F5 Gene

MalaCards: The human disease database

(96) MalaCards diseases for F5 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
factor v deficiency
  • parahemophilia
thrombophilia due to activated protein c resistance
  • thph2
pregnancy loss, recurrent 1
  • pregnancy loss, recurrent, susceptibility to, 1
budd-chiari syndrome
  • bdchs
stroke, ischemic
  • cerebrovascular accident
- elite association - COSMIC cancer census association via MalaCards
Search F5 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

FA5_HUMAN
  • Factor V deficiency (FA5D) [MIM:227400]: A blood coagulation disorder leading to a hemorrhagic diathesis known as parahemophilia. {ECO:0000269 PubMed:10942390, ECO:0000269 PubMed:12393490}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Thrombophilia due to activated protein C resistance (THPH2) [MIM:188055]: A hemostatic disorder due to defective degradation of factor V by activated protein C. It is characterized by a poor anticoagulant response to activated protein C resulting in tendency to thrombosis. {ECO:0000269 PubMed:10391209, ECO:0000269 PubMed:10942390, ECO:0000269 PubMed:11435304, ECO:0000269 PubMed:11858490, ECO:0000269 PubMed:14617013, ECO:0000269 PubMed:14695241, ECO:0000269 PubMed:16710414, ECO:0000269 PubMed:8164741, ECO:0000269 PubMed:9454742}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Budd-Chiari syndrome (BDCHS) [MIM:600880]: A syndrome caused by obstruction of hepatic venous outflow involving either the hepatic veins or the terminal segment of the inferior vena cava. Obstructions are generally caused by thrombosis and lead to hepatic congestion and ischemic necrosis. Clinical manifestations observed in the majority of patients include hepatomegaly, right upper quadrant pain and abdominal ascites. Budd-Chiari syndrome is associated with a combination of disease states including primary myeloproliferative syndromes and thrombophilia due to factor V Leiden, protein C deficiency and antithrombin III deficiency. Budd-Chiari syndrome is a rare but typical complication in patients with polycythemia vera. {ECO:0000269 PubMed:9245936}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Ischemic stroke (ISCHSTR) [MIM:601367]: A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. {ECO:0000269 PubMed:15534175}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Pregnancy loss, recurrent, 1 (RPRGL1) [MIM:614389]: A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions. {ECO:0000269 PubMed:11018168}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Genatlas disease for F5 Gene

parahemophilia

Additional Disease Information for F5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with F5: view

Publications for F5 Gene

  1. Impact of genetic polymorphisms on platelet function and aspirin resistance. (PMID: 19923980) Pamukcu B … Nisanci Y (Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2010) 3 22 44 58
  2. Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants. (PMID: 20161734) Bentley P … Sharma P (PloS one 2010) 3 22 44 58
  3. Risk factors for failure of heparin thromboprophylaxis in patients with acute traumatic spinal cord injury. (PMID: 19853891) Rubin-Asher D … Lubetsky A (Thrombosis research 2010) 3 22 44 58
  4. Coagulation abnormalities in Legg-Calvé-Perthes disease. (PMID: 20048104) Vosmaer A … Cannegieter SC (The Journal of bone and joint surgery. American volume 2010) 3 22 44 58
  5. Clinical factors such as B-type natriuretic peptide link to factor VII, endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women. (PMID: 19560472) Funami J … Iguchi A (Life sciences 2009) 3 22 44 58

Products for F5 Gene

Sources for F5 Gene

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