Aliases for EXOC8 Gene
External Ids for EXOC8 Gene
Previous GeneCards Identifiers for EXOC8 Gene
This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016]
GeneCards Summary for EXOC8 Gene
EXOC8 (Exocyst Complex Component 8) is a Protein Coding gene. Diseases associated with EXOC8 include Bardet-Biedl Syndrome 18 and Babesiosis. Among its related pathways are Peptide hormone metabolism and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include Ral GTPase binding.
UniProtKB/Swiss-Prot for EXOC8 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.