Aliases for EXOC6B Gene
External Ids for EXOC6B Gene
Previous HGNC Symbols for EXOC6B Gene
Previous GeneCards Identifiers for EXOC6B Gene
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016]
GeneCards Summary for EXOC6B Gene
EXOC6B (Exocyst Complex Component 6B) is a Protein Coding gene. Diseases associated with EXOC6B include Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 and Spondyloepimetaphyseal Dysplasia With Joint Laxity. Among its related pathways are Cytoskeleton remodeling_RalA regulation pathway. An important paralog of this gene is EXOC6.
UniProtKB/Swiss-Prot Summary for EXOC6B Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.