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Aliases for EXOC3-AS1 Gene

Subcategory (RNA class) for EXOC3-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for EXOC3-AS1 Gene

  • EXOC3 Antisense RNA 1 2 3 4 5
  • C5orf55 3 4
  • Chromosome 5 Open Reading Frame 55 2
  • Uncharacterized Protein C5orf55 3
  • EXOC3 Antisense Gene Protein 1 4

External Ids for EXOC3-AS1 Gene

Previous HGNC Symbols for EXOC3-AS1 Gene

  • C5orf55

Summaries for EXOC3-AS1 Gene

GeneCards Summary for EXOC3-AS1 Gene

EXOC3-AS1 (EXOC3 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for EXOC3-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EXOC3-AS1 Gene

Genomics for EXOC3-AS1 Gene

GeneHancer (GH) Regulatory Elements for EXOC3-AS1 Gene

Promoters and enhancers for EXOC3-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I000442 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 558.6 -0.2 -197 2.6 HDGF PKNOX1 SMAD1 ATF1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF48 EXOC3 EXOC3-AS1 GC05P000439 PP7080
GH05I000413 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 12 +27.9 27859 3.2 HDGF NCOA2 POLR2B GLIS2 GATA2 KLF7 ATF7 SP3 SMARCB1 ZNF610 SLC9A3-AS1 EXOC3 EXOC3-AS1 ENSG00000250645 GC05M000414 LOC100310782 AHRR
GH05I000470 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 8.3 -30.0 -30008 4.4 ARNT SIN3A ZNF2 ZNF766 ZNF207 DEK SP3 NFYC MXD4 SMARCB1 SLC9A3-AS1 PP7080 EXOC3 ENSG00000250645 EXOC3-AS1 SLC9A3
GH05I000411 Enhancer 0.9 ENCODE dbSUPER 12 +31.6 31553 1.1 RNF2 MAX CEBPB BMI1 CEBPG EP300 ATF4 JUND ZNF512B POLR2A EXOC3 EXOC3-AS1 SLC9A3-AS1 GC05M000414 LOC100310782 AHRR
GH05I000424 Enhancer 1.2 FANTOM5 Ensembl dbSUPER 8.2 +18.5 18459 1 HDGF BACH1 EBF1 ZIC2 KLF5 ZNF335 ZFHX2 POLR2A ZNF143 ATF7 EXOC3 SLC9A3-AS1 AHRR PDCD6 EXOC3-AS1 ZDHHC11 PIR58727 GC05M000432 PIR54496
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around EXOC3-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for EXOC3-AS1 Gene

Genomic Locations for EXOC3-AS1 Gene
chr5:441,498-443,160
(GRCh38/hg38)
Size:
1,663 bases
Orientation:
Minus strand
chr5:441,613-443,258
(GRCh37/hg19)

Genomic View for EXOC3-AS1 Gene

Genes around EXOC3-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EXOC3-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EXOC3-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EXOC3-AS1 Gene

Proteins for EXOC3-AS1 Gene

  • Protein details for EXOC3-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N2X6-EXAS1_HUMAN
    Recommended name:
    Uncharacterized protein EXOC3-AS1
    Protein Accession:
    Q8N2X6
    Secondary Accessions:
    • Q96CR9

    Protein attributes for EXOC3-AS1 Gene

    Size:
    119 amino acids
    Molecular mass:
    12661 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH14011.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for EXOC3-AS1 Gene

Post-translational modifications for EXOC3-AS1 Gene

No data available for DME Specific Peptides for EXOC3-AS1 Gene

Domains & Families for EXOC3-AS1 Gene

Protein Domains for EXOC3-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EXOC3-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EXOC3-AS1 Gene

Function for EXOC3-AS1 Gene

Phenotypes From GWAS Catalog for EXOC3-AS1 Gene

Gene Ontology (GO) - Molecular Function for EXOC3-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with EXOC3-AS1: view

Phenotypes for EXOC3-AS1 Gene

GenomeRNAi human phenotypes for EXOC3-AS1:
genes like me logo Genes that share phenotypes with EXOC3-AS1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for EXOC3-AS1 Gene

Localization for EXOC3-AS1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for EXOC3-AS1 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for EXOC3-AS1 gene
Compartment Confidence
extracellular 4
mitochondrion 2
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for EXOC3-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with EXOC3-AS1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for EXOC3-AS1 Gene

Pathways & Interactions for EXOC3-AS1 Gene

SuperPathways for EXOC3-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for EXOC3-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EXOC3-AS1 Gene

Drugs & Compounds for EXOC3-AS1 Gene

No Compound Related Data Available

Transcripts for EXOC3-AS1 Gene

mRNA/cDNA for EXOC3-AS1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for EXOC3-AS1 Gene

No ASD Table

Relevant External Links for EXOC3-AS1 Gene

GeneLoc Exon Structure for
EXOC3-AS1
ECgene alternative splicing isoforms for
EXOC3-AS1

Expression for EXOC3-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for EXOC3-AS1 Gene

Evidence on tissue expression from TISSUES for EXOC3-AS1 Gene

  • Intestine(4.1)
genes like me logo Genes that share expression patterns with EXOC3-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for EXOC3-AS1 Gene

Orthologs for EXOC3-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for EXOC3-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC750771 33
  • 97.76 (n)
C5orf55 34
  • 94 (a)
OneToOne
Species where no ortholog for EXOC3-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for EXOC3-AS1 Gene

ENSEMBL:
Gene Tree for EXOC3-AS1 (if available)
TreeFam:
Gene Tree for EXOC3-AS1 (if available)

Paralogs for EXOC3-AS1 Gene

No data available for Paralogs for EXOC3-AS1 Gene

Variants for EXOC3-AS1 Gene

Sequence variations from dbSNP and Humsavar for EXOC3-AS1 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000457984 -- 445,059(-) G/A upstream_transcript_variant
rs1002778668 -- 442,036(-) T/A non_coding_transcript_variant
rs1003095856 -- 441,793(-) C/A downstream_transcript_variant
rs1003126825 -- 444,856(-) G/A upstream_transcript_variant
rs10035612 -- 442,471(-) G/A/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for EXOC3-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv9479n54 CNV gain 21841781
esv2752071 CNV gain 17911159
esv2759315 CNV loss 17122850
esv3603744 CNV gain 21293372
esv3603745 CNV gain 21293372
esv3894107 CNV gain 25118596
nsv1019215 CNV gain 25217958
nsv1027279 CNV gain 25217958
nsv1030767 CNV gain 25217958
nsv1032584 CNV gain 25217958
nsv1032824 CNV gain 25217958
nsv1133013 OTHER inversion 24896259
nsv1147234 OTHER inversion 26484159
nsv461889 CNV gain 19166990
nsv461890 CNV gain 19166990
nsv4673 CNV insertion 18451855
nsv596626 CNV gain 21841781
nsv830183 CNV gain+loss 17160897
nsv830184 CNV gain 17160897

Variation tolerance for EXOC3-AS1 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.84; 67.18% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for EXOC3-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EXOC3-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EXOC3-AS1 Gene

Disorders for EXOC3-AS1 Gene

Additional Disease Information for EXOC3-AS1

No disorders were found for EXOC3-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EXOC3-AS1 Gene

Publications for EXOC3-AS1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual JF … Vidal M (Nature 2005) 3 58
  4. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J … Rubin EM (Nature 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for EXOC3-AS1 Gene

Sources for EXOC3-AS1 Gene

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