Aliases for EXOC3 Gene
External Ids for EXOC3 Gene
Previous HGNC Symbols for EXOC3 Gene
Previous GeneCards Identifiers for EXOC3 Gene
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
GeneCards Summary for EXOC3 Gene
EXOC3 (Exocyst Complex Component 3) is a Protein Coding gene. Diseases associated with EXOC3 include Lynch Syndrome. Among its related pathways are Peptide hormone metabolism and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include SNARE binding. An important paralog of this gene is EXOC3L1.
UniProtKB/Swiss-Prot Summary for EXOC3 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.