Aliases for EXOC2 Gene
Aliases for EXOC2 Gene
External Ids for EXOC2 Gene
- HGNC: 24968
- Entrez Gene: 55770
- Ensembl: ENSG00000112685
- OMIM: 615329
- UniProtKB: Q96KP1
Previous HGNC Symbols for EXOC2 Gene
- SEC5L1
Previous GeneCards Identifiers for EXOC2 Gene
- GC06M000431
Summaries for EXOC2 Gene
-
The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
GeneCards Summary for EXOC2 Gene
EXOC2 (Exocyst Complex Component 2) is a Protein Coding gene. Among its related pathways are Organelle biogenesis and maintenance and Sertoli-Sertoli Cell Junction Dynamics. Gene Ontology (GO) annotations related to this gene include protein kinase binding and Ral GTPase binding.
UniProtKB/Swiss-Prot for EXOC2 Gene
-
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Additional gene information for EXOC2 Gene
- Monarch Initiative
- Search for EXOC2 at DataMed
- Search for EXOC2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EXOC2 Gene
Genomics for EXOC2 Gene
GeneHancer (GH) Regulatory Elements for EXOC2 Gene
Promoters and enhancers for EXOC2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around EXOC2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the EXOC2 gene promoter:
-
- FOXF2
- AML1a
- FOXD3
- AREB6
- Egr-4
- IRF-1
- FOXC1
- FOXO1a
- FOXO1
Regulatory Element Products
Genomic Locations for EXOC2 Gene
Genomic Locations for EXOC2 Gene
- chr6:485,133-693,141
- (GRCh38/hg38)
- Size:
- 208,009 bases
- Orientation:
- Minus strand
- chr6:485,133-693,117
- (GRCh37/hg19)
- Size:
- 207,985 bases
- Orientation:
- Minus strand
Genomic View for EXOC2 Gene
Genes around EXOC2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p25.3 by Entrez Gene
- 6p25.3 by HGNC
- 6p25.3 by Ensembl
EXOC2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for EXOC2 Gene
Proteins for EXOC2 Gene
-
Protein details for EXOC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96KP1-EXOC2_HUMAN
- Recommended name:
- Exocyst complex component 2
- Protein Accession:
- Q96KP1
- B2RBE6
- Q5JPC8
- Q96AN6
- Q9NUZ8
- Q9UJM7
Protein attributes for EXOC2 Gene
- Size:
- 924 amino acids
- Molecular mass:
- 104066 Da
- Quaternary structure:
-
- The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with EXOC3L1 (By similarity). Interacts with GNEFR/DELGEF; this interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP (PubMed:12459492). Interacts with RALA and RALB (PubMed:18756269, PubMed:19166349).
- SequenceCaution:
-
- Sequence=BAA91963.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for EXOC2 Gene
Post-translational modifications for EXOC2 Gene
Other Protein References for EXOC2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for EXOC2
- Novus Biologicals Antibodies for EXOC2
-
Abcam antibodies for EXOC2
- Invitrogen Antibodies for EXOC2
- GeneTex EXOC2 Antibody for EXOC2
-
Santa Cruz Biotechnology (SCBT) Antibodies for EXOC2
Protein Products
-
OriGene Purified Proteins for EXOC2
- Search Origene for MassSpec and Protein Over-expression Lysates for EXOC2
- Origene Custom Protein Services for EXOC2
- Search GeneTex for Proteins for EXOC2
-
Abcam proteins for EXOC2
Assay Products
No data available for DME Specific Peptides for EXOC2 Gene
Domains & Families for EXOC2 Gene
Gene Families for EXOC2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transporters
Protein Domains for EXOC2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for EXOC2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96KP1UniProtKB/Swiss-Prot:
EXOC2_HUMAN :- Interacts with RALA through the TIG domain.
- Belongs to the SEC5 family.
- Domain:
-
- Interacts with RALA through the TIG domain.
- Family:
-
- Belongs to the SEC5 family.
Function for EXOC2 Gene
Molecular function for EXOC2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Phenotypes From GWAS Catalog for EXOC2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12459492 |
| GO:0017160 | Ral GTPase binding | IPI | 24056301 |
| GO:0019901 | protein kinase binding | IPI | 24056301 |
| GO:0047485 | protein N-terminus binding | IEA | -- |
Phenotypes for EXOC2 Gene
- GenomeRNAi human phenotypes for EXOC2:
-
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Increased G1 DNA content
- Decreased viability in esophageal squamous lineage
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Resistant to vaccinia virus (VACV-A4L) infection
- Mildly decreased CFP-tsO45G cell surface transport
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for EXOC2
-
CRISPR Products
-
OriGene CRISPR knockouts for EXOC2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EXOC2
- genomics-online: gRNA clones - Search results for available EXOC2 gene related products
- Applied Biological Materials CRISPR for EXOC2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for EXOC2
- GenScript: Design CRISPR guide RNA sequences for EXOC2
miRNA for EXOC2 Gene
- miRTarBase miRNAs that target EXOC2
-
- hsa-mir-155-5p (MIRT020620)
- hsa-mir-1-3p (MIRT023654)
- hsa-mir-615-3p (MIRT039714)
- hsa-mir-30d-5p (MIRT047777)
- hsa-mir-30a-5p (MIRT049928)
- hsa-mir-570-3p (MIRT450598)
- hsa-mir-5582-3p (MIRT450599)
- hsa-mir-548as-3p (MIRT450600)
- hsa-mir-548x-3p (MIRT450601)
- hsa-mir-548j-3p (MIRT450602)
- hsa-mir-548aq-3p (MIRT450603)
- hsa-mir-548am-3p (MIRT450604)
- hsa-mir-548aj-3p (MIRT450605)
- hsa-mir-548ah-3p (MIRT450606)
- hsa-mir-548ae-3p (MIRT450607)
- hsa-mir-659-3p (MIRT707667)
- hsa-mir-607 (MIRT707668)
- hsa-mir-3671 (MIRT707669)
- hsa-mir-563 (MIRT707670)
- hsa-mir-380-5p (MIRT707671)
- hsa-mir-203a-3p (MIRT707672)
- hsa-mir-153-5p (MIRT707673)
- hsa-mir-1250-3p (MIRT707674)
- hsa-mir-7853-5p (MIRT707675)
- hsa-mir-105-5p (MIRT707676)
- hsa-mir-1252-3p (MIRT707677)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EXOC2
- Browse OriGene Inhibitory RNA Products For EXOC2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EXOC2
- genomics-online: shRNA clones - Search results for available EXOC2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for EXOC2
- VectorBuilder custom plasmid, inducible vectors for EXOC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for EXOC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for EXOC2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EXOC2
- genomics-online: cdna clones - Search results for available EXOC2 gene related products
- orf clones - Search results for available EXOC2 gene related products
- Applied Biological Materials Clones for EXOC2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for EXOC2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for EXOC2 Gene
Localization for EXOC2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for EXOC2 Gene
- Midbody, Midbody ring. Note=Recruitment to the midbody does not require RALA, nor RALB (PubMed:18756269). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). {ECO:0000269 PubMed:16213214, ECO:0000269 PubMed:18756269}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 5 |
| golgi apparatus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endosome | 1 |
- Vesicles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000145 | exocyst | IDA | 24056301 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | HDA | 19946888 |
| GO:0090543 | Flemming body | IEA | -- |
Pathways & Interactions for EXOC2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cargo trafficking to the periciliary membrane | ||
| 2 | Organelle biogenesis and maintenance |
.56
|
|
| 3 | Peptide hormone metabolism | ||
| 4 | Vesicle-mediated transport | ||
| 5 | Ras signaling pathway | ||
Pathways by source for EXOC2 Gene
3 BioSystems pathways for EXOC2 Gene
10 Reactome pathways for EXOC2 Gene
1 KEGG pathway for EXOC2 Gene
2 GeneGo (Thomson Reuters) pathways for EXOC2 Gene
3 Qiagen pathways for EXOC2 Gene
Interacting Proteins for EXOC2 Gene
Selected Interacting proteins:
Q96KP1-EXOC2_HUMAN
ENSP00000230449
for EXOC2 Gene via
UniProtKB
STRING
MINT
IID
GPS-Prot Interaction Network for EXOC2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001927 | exocyst assembly | IBA | -- |
| GO:0006887 | exocytosis | IEA | -- |
| GO:0006893 | Golgi to plasma membrane transport | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:2000535 | regulation of entry of bacterium into host cell | IMP | 20579884 |
No data available for SIGNOR curated interactions for EXOC2 Gene
Transcripts for EXOC2 Gene
mRNA/cDNA for EXOC2 Gene
- (10) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (127) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000230449 4449 bps (uc003mtd.5)
- ENST00000443083 720 bps (uc063ljj.1)
- ENST00000475028 536 bps (uc063ljk.1)
Unigene Clusters for EXOC2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for EXOC2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EXOC2
- genomics-online: gRNA clones - Search results for available EXOC2 gene related products
- Applied Biological Materials CRISPR for EXOC2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for EXOC2
- GenScript: Design CRISPR guide RNA sequences for EXOC2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EXOC2
- Browse OriGene Inhibitory RNA Products For EXOC2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EXOC2
- genomics-online: shRNA clones - Search results for available EXOC2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for EXOC2
- VectorBuilder custom plasmid, inducible vectors for EXOC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for EXOC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for EXOC2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EXOC2
- genomics-online: cdna clones - Search results for available EXOC2 gene related products
- orf clones - Search results for available EXOC2 gene related products
- Applied Biological Materials Clones for EXOC2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: |
| ExUns: | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32a | · | 32b | ^ | 33 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||
| SP2: | - | - | - | ||||||||||||||
| SP3: | |||||||||||||||||
| SP4: | |||||||||||||||||
| SP5: |
Expression for EXOC2 Gene
This gene is overexpressed in Bone (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for EXOC2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of EXOC2 Gene:
EXOC2SOURCE GeneReport for Unigene cluster for EXOC2 Gene:
Hs.484412mRNA Expression by UniProt/SwissProt for EXOC2 Gene:
Q96KP1-EXOC2_HUMAN
Tissue specificity:
Widely expressed with highest levels in brain and placenta.
Evidence on tissue expression from TISSUES for EXOC2 Gene
- Nervous system(4.6)
- Lymph node(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for EXOC2
-
OriGene qPCR primer pairs for EXOC2
- genomics-online: primer clones - Search results for available EXOC2 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for EXOC2 Gene
Orthologs for EXOC2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | EXOC2 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | EXOC2 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | EXOC2 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | EXOC2 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Exoc2 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Exoc2 33 |
|
||
| cow (Bos Taurus) |
Mammalia | EXOC2 34 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | EXOC2 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | EXOC2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | exoc2 33 |
|
||
| Str.10084 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | exoc2 34 33 |
|
OneToOne | |
| zgc63558 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4905 33 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001733 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | sec5 34 33 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | sec-5 34 33 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | SEC5A 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os04g0421900 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| Cin.12002 33 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.12002 33 |
|
- Species where no ortholog for EXOC2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for EXOC2 Gene
- ENSEMBL:
- Gene Tree for EXOC2 (if available)
- TreeFam:
- Gene Tree for EXOC2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for EXOC2: view image
Paralogs for EXOC2 Gene
No data available for Paralogs for EXOC2 Gene
Variants for EXOC2 Gene
| SNP ID | Clin | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs145867129 | uncertain-significance, Malignant tumor of prostate | 576,834(-) | C/G/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000027784 | -- | 630,616(-) | A/G | intron_variant | |
| rs1000029113 | -- | 691,698(-) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000030068 | -- | 673,623(-) | T/A/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000063788 | -- | 554,090(-) | G/A | intron_variant |
Residual Variation Intolerance Score:
3.34% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.45;
43.17% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for EXOC2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- EXOC2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EXOC2 Gene
Disorders for EXOC2 Gene
Additional Disease Information for EXOC2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for EXOC2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EXOC2 Gene
Publications for EXOC2 Gene
- DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion. (PMID: 12459492) Sjölinder M … Ponstingl H (FEBS letters 2002) 2 3 4 22 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. (PMID: 20570966) McGovern DP … International IBD Genetics Consortium (Human molecular genetics 2010) 3 44 58
- Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding. (PMID: 19166349) Fenwick RB … Owen D (Biochemistry 2009) 3 4 58
- Genome-wide association study of tanning phenotype in a population of European ancestry. (PMID: 19340012) Nan H … Han J (The Journal of investigative dermatology 2009) 3 44 58
Products for EXOC2 Gene
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- Custom Antibody ServicesOriGene Antibodies for EXOC2
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- OriGene qPCR primer pairs and template standards for EXOC2
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- GenScript: Design CRISPR guide RNA sequences for EXOC2
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- Novus Biologicals proteins and lysates for EXOC2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
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- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder custom plasmid, inducible vectors for EXOC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for EXOC2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for EXOC2
- antibodies-online: Search results for 36 available EXOC2 Antibodies ranked by validation data
- Compare Top EXOC2 Antibodies
- antibodies-online: Search results for available EXOC2 related products ranked by validation data
- antibodies-online: Search results for available EXOC2 related products ranked by validation data
- GeneTex EXOC2 Antibody for EXOC2
- Search GeneTex for Proteins for EXOC2
- Santa Cruz Biotechnology (SCBT) Antibodies for EXOC2
- Search Santa Cruz Biotechnology (SCBT) for EXOC2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for EXOC2
- Horizon Cell Lines for EXOC2
- genomics-online: cdna clones - Search results for available EXOC2 gene related products
- orf clones - Search results for available EXOC2 gene related products
- genomics-online: gRNA clones - Search results for available EXOC2 gene related products
- genomics-online: primer clones - Search results for available EXOC2 gene related products
- genomics-online: shRNA clones - Search results for available EXOC2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EXOC2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EXOC2
- GeneCopoeia miRNA 3'UTR Target clone products for EXOC2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EXOC2
Sources for EXOC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt