Aliases for ETV4 Gene
External Ids for ETV4 Gene
Previous GeneCards Identifiers for ETV4 Gene
GeneCards Summary for ETV4 Gene
ETV4 (ETS Variant Transcription Factor 4) is a Protein Coding gene. Diseases associated with ETV4 include Ewing Sarcoma and Testicular Seminoma. Among its related pathways are Signaling by GPCR and Transcriptional misregulation in cancer. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is ETV1.
UniProtKB/Swiss-Prot Summary for ETV4 Gene
Transcriptional activator (PubMed:19307308, PubMed:31552090). May play a role in keratinocyte differentiation (PubMed:31552090).
(Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator; the core-binding sequence is 5'-[AC]GGA[AT]GT-3'.