Aliases for ETS2 Gene
- ETS Proto-Oncogene 2, Transcription Factor 2 3 5
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 2 2 3
- Protein C-Ets-2 3 4
- V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (Avian) 2
- V-Ets Avian Erythroblastosis Virus E2 Oncogene Homolog 2 3
- V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 3
- Oncogene ETS-2 3
- ETS2IT1 3
External Ids for ETS2 Gene
Previous GeneCards Identifiers for ETS2 Gene
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
GeneCards Summary for ETS2 Gene
ETS2 (ETS Proto-Oncogene 2, Transcription Factor) is a Protein Coding gene. Diseases associated with ETS2 include Choriocarcinoma and Down Syndrome. Among its related pathways are Human T-cell leukemia virus 1 infection and C-MYB transcription factor network. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is ETS1.
UniProtKB/Swiss-Prot for ETS2 Gene
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.