Aliases for ETNK1 Gene
External Ids for ETNK1 Gene
Previous GeneCards Identifiers for ETNK1 Gene
This gene encodes an ethanolamine kinase, which functions in the first committed step of the phosphatidylethanolamine synthesis pathway. This cytosolic enzyme is specific for ethanolamine and exhibits negligible kinase activity on choline. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for ETNK1 Gene
ETNK1 (Ethanolamine Kinase 1) is a Protein Coding gene. Diseases associated with ETNK1 include Atypical Chronic Myeloid Leukemia and Systemic Mastocytosis. Among its related pathways are Glycerophospholipid biosynthesis and phosphatidylethanolamine biosynthesis II. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and ethanolamine kinase activity. An important paralog of this gene is ETNK2.
UniProtKB/Swiss-Prot Summary for ETNK1 Gene
Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.