Aliases for ERVV-2 Gene
External Ids for ERVV-2 Gene
Previous GeneCards Identifiers for ERVV-2 Gene
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on human chromosome 19 that has inactivating mutations in the gag and pol genes. This envelope glycoprotein gene appears to have been selectively preserved. The gene's protein product is expressed in the placenta and acts as a syncytin in Old World monkeys, but has lost the fusogenic activity in humans and other primate lineages. [provided by RefSeq, Jun 2015]
GeneCards Summary for ERVV-2 Gene
ERVV-2 (Endogenous Retrovirus Group V Member 2, Envelope) is a Protein Coding gene. An important paralog of this gene is ERVV-1.