Aliases for ERP29 Gene
External Ids for ERP29 Gene
Previous HGNC Symbols for ERP29 Gene
Previous GeneCards Identifiers for ERP29 Gene
This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
GeneCards Summary for ERP29 Gene
ERP29 (Endoplasmic Reticulum Protein 29) is a Protein Coding gene. Diseases associated with ERP29 include Intrahepatic Cholestasis. Among its related pathways are Protein processing in endoplasmic reticulum. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein disulfide isomerase activity.
UniProtKB/Swiss-Prot for ERP29 Gene
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.