Aliases for ERN2 Gene
External Ids for ERN2 Gene
Previous GeneCards Identifiers for ERN2 Gene
GeneCards Summary for ERN2 Gene
ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2) is a Protein Coding gene. Diseases associated with ERN2 include Orbital Granuloma and Ileocolitis. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is ERN1.
UniProtKB/Swiss-Prot Summary for ERN2 Gene
Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.