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Aliases for ERICH4 Gene
Aliases for ERICH4 Gene
External Ids for ERICH4 Gene
- HGNC: 34497
- Entrez Gene: 100170765
- Ensembl: ENSG00000204978
- UniProtKB: A6NGS2
Previous HGNC Symbols for ERICH4 Gene
- C19orf69
Previous GeneCards Identifiers for ERICH4 Gene
- GC19P041950
Summaries for ERICH4 Gene
GeneCards Summary for ERICH4 Gene
ERICH4 (Glutamate Rich 4) is a Protein Coding gene.
Additional gene information for ERICH4 Gene
- HGNC(34497)
- Entrez Gene(100170765)
- Ensembl(ENSG00000204978)
- UniProtKB(A6NGS2)
- Open Targets Platform(ENSG00000204978)
- Search for ERICH4 at DataMed
- Search for ERICH4 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ERICH4 Gene
Genomics for ERICH4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ERICH4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ERICH4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ERICH4
Genomic Locations for ERICH4 Gene
Genomic Locations for ERICH4 Gene
- chr19:41,442,426-41,444,765
- (GRCh38/hg38)
- Size:
- 2,340 bases
- Orientation:
- Plus strand
- chr19:41,949,063-41,950,670
- (GRCh37/hg19)
- Size:
- 1,608 bases
- Orientation:
- Plus strand
Genomic View for ERICH4 Gene
Genes around ERICH4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.2 by HGNC
- 19q13.2 by Entrez Gene
- 19q13.2 by Ensembl
ERICH4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ERICH4 Gene
Proteins for ERICH4 Gene
-
Protein details for ERICH4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NGS2-ERIC4_HUMAN
- Recommended name:
- Glutamate-rich protein 4
- Protein Accession:
- A6NGS2
Protein attributes for ERICH4 Gene
- Size:
- 130 amino acids
- Molecular mass:
- 14477 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for ERICH4 Gene
No Post-translational modifications
Other Protein References for ERICH4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-ERICH4 (aa 50-100) polyclonal antibody
- Novus Biologicals Antibodies for ERICH4
- Invitrogen Antibodies for ERICH4 (AFLGC-ERICH4)
Protein Products
-
OriGene Purified Proteins for ERICH4
- Search Origene for MassSpec and Protein Over-expression Lysates for ERICH4
- Origene Custom Protein Services for ERICH4
- Novus Biologicals proteins for ERICH4
No data available for DME Specific Peptides for ERICH4 Gene
Domains & Families for ERICH4 Gene
Gene Families for ERICH4 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ERICH4 Gene
Function for ERICH4 Gene
Phenotypes From GWAS Catalog for ERICH4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ERICH4 - Select products 50% OFF >
- * ERICH4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ERICH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERICH4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERICH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERICH4
- Browse OriGene Inhibitory RNA Products For ERICH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4
Clone Products
- Applied Biological Materials (abm): Clones for ERICH4 - Select products 50% OFF >
- * ERICH4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ERICH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERICH4
Cell Line Products
-
Horizon Cell Lines for ERICH4
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ERICH4 Gene
Localization for ERICH4 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 2 |
| nucleus | 2 |
| cytosol | 2 |
- Cytosol (2)
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ERICH4 Gene
Pathways & Interactions for ERICH4 Gene
Interacting Proteins for ERICH4 Gene
Selected Interacting proteins:
A6NGS2-ERIC4_HUMAN
ENSP00000367429
for ERICH4 Gene via
UniProtKB
STRING
GPS-Prot Interaction Network for ERICH4
No data available for Pathways by source and SIGNOR curated interactions for ERICH4 Gene
Transcripts for ERICH4 Gene
mRNA/cDNA for ERICH4 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000378187 948 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ERICH4 - Select products 50% OFF >
- * ERICH4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ERICH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERICH4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERICH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERICH4
- Browse OriGene Inhibitory RNA Products For ERICH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4
Clone Products
- Applied Biological Materials (abm): Clones for ERICH4 - Select products 50% OFF >
- * ERICH4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ERICH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERICH4
Relevant External Links for ERICH4 Gene
- GeneLoc Exon Structure for
- ERICH4
Expression for ERICH4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
mRNA differential expression in normal tissues according to GTEx for ERICH4 Gene
This gene is overexpressed in Small Intestine - Terminal Ileum (x13.4) and Kidney - Cortex (x12.2).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ERICH4
Primer Products
-
OriGene qPCR primer pairs for ERICH4
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ERICH4 Gene
Orthologs for ERICH4 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C19H19orf69 30 |
|
||
| C19orf69 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | ERICH4 30 |
|
||
| C19orf69 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | ERICH4 30 |
|
||
| C19orf69 31 |
|
OneToOne | |||
| Rat (Rattus norvegicus) |
Mammalia | LOC685046 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Gm7092 30 31 |
|
OneToOne | |
| Erich4 17 |
|
- Species where no ortholog for ERICH4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for ERICH4 Gene
- ENSEMBL:
- Gene Tree for ERICH4 (if available)
- TreeFam:
- Gene Tree for ERICH4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ERICH4: view image
Paralogs for ERICH4 Gene
No data available for Paralogs for ERICH4 Gene
Variants for ERICH4 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3644380 | CNV | loss | 21293372 |
Gene Damage Index Score:
3.09;
50.92% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ERICH4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ERICH4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ERICH4 Gene
Disorders for ERICH4 Gene
Additional Disease Information for ERICH4
No disorders were found for ERICH4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ERICH4 Gene
Publications for ERICH4 Gene
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
ExternalLinks
Products for ERICH4 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ERICH4
- Search Origene for MassSpec and Protein Over-expression Lysates for ERICH4
- Origene Custom Protein Services for ERICH4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERICH4
- Browse OriGene Inhibitory RNA Products For ERICH4
- OriGene qPCR primer pairs for ERICH4
- OriGene CRISPR knockouts for ERICH4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ERICH4
- Sino Biological Human cDNA Clone for ERICH4
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ERICH4
- Novus Biologicals proteins for ERICH4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for ERICH4 (AFLGC-ERICH4)
- VectorBuilder Custom and pre-made DNA vectors for ERICH4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ERICH4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ERICH4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ERICH4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ERICH4
- Horizon Cell Lines for ERICH4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERICH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERICH4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ERICH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4
Sources for ERICH4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB