Aliases for ERICH4 Gene
Aliases for ERICH4 Gene
External Ids for ERICH4 Gene
- HGNC: 34497
- Entrez Gene: 100170765
- Ensembl: ENSG00000204978
- UniProtKB: A6NGS2
Previous HGNC Symbols for ERICH4 Gene
- C19orf69
Previous GeneCards Identifiers for ERICH4 Gene
- GC19P041950
Summaries for ERICH4 Gene
GeneCards Summary for ERICH4 Gene
ERICH4 (Glutamate Rich 4) is a Protein Coding gene.
Additional gene information for ERICH4 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERICH4 Gene
Genomics for ERICH4 Gene
GeneHancer (GH) Regulatory Elements for ERICH4 Gene
Promoters and enhancers for ERICH4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ERICH4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ERICH4 Gene
Genomic Locations for ERICH4 Gene
- chr19:41,443,158-41,444,765
- (GRCh38/hg38)
- Size:
- 1,608 bases
- Orientation:
- Plus strand
- chr19:41,949,063-41,950,670
- (GRCh37/hg19)
- Size:
- 1,608 bases
- Orientation:
- Plus strand
Genomic View for ERICH4 Gene
Genes around ERICH4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.2 by Entrez Gene
- 19q13.2 by HGNC
- 19q13.2 by Ensembl
ERICH4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ERICH4 Gene
Proteins for ERICH4 Gene
-
Protein details for ERICH4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NGS2-ERIC4_HUMAN
- Recommended name:
- Glutamate-rich protein 4
- Protein Accession:
- A6NGS2
Protein attributes for ERICH4 Gene
- Size:
- 130 amino acids
- Molecular mass:
- 14477 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for ERICH4 Gene
No Post-translational modifications
Other Protein References for ERICH4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ERICH4
- Invitrogen Antibodies for ERICH4
- Search GeneTex for Antibodies for ERICH4
Protein Products
-
OriGene Purified Proteins for ERICH4
- Search Origene for MassSpec and Protein Over-expression Lysates for ERICH4
- Origene Custom Protein Services for ERICH4
- Novus Biologicals proteins for ERICH4
- Search GeneTex for Proteins for ERICH4
Assay Products
No data available for DME Specific Peptides for ERICH4 Gene
Domains & Families for ERICH4 Gene
Gene Families for ERICH4 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ERICH4 Gene
Function for ERICH4 Gene
Phenotypes From GWAS Catalog for ERICH4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ERICH4
-
CRISPR Products
-
OriGene CRISPR knockouts for ERICH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERICH4
- genomics-online: gRNA clones - Search results for available C19orf69 gene related products
- Applied Biological Materials CRISPR for ERICH4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERICH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERICH4
- Browse OriGene Inhibitory RNA Products For ERICH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4
- genomics-online: shRNA clones - Search results for available C19orf69 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ERICH4
- VectorBuilder custom plasmid, inducible vectors for ERICH4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ERICH4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERICH4
- genomics-online: cdna clones - Search results for available C19orf69 gene related products
- orf clones - Search results for available C19orf69 gene related products
- Applied Biological Materials Clones for ERICH4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ERICH4
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ERICH4 Gene
Localization for ERICH4 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 3 |
| extracellular | 2 |
- Cytosol (2)
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ERICH4 Gene
Transcripts for ERICH4 Gene
mRNA/cDNA for ERICH4 Gene
- (2) REFSEQ mRNAs :
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000378187 946 bps (uc010xwc.2)
CRISPR Products
-
OriGene CRISPR knockouts for ERICH4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERICH4
- genomics-online: gRNA clones - Search results for available C19orf69 gene related products
- Applied Biological Materials CRISPR for ERICH4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERICH4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERICH4
- Browse OriGene Inhibitory RNA Products For ERICH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4
- genomics-online: shRNA clones - Search results for available C19orf69 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ERICH4
- VectorBuilder custom plasmid, inducible vectors for ERICH4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ERICH4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERICH4
- genomics-online: cdna clones - Search results for available C19orf69 gene related products
- orf clones - Search results for available C19orf69 gene related products
- Applied Biological Materials Clones for ERICH4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for ERICH4 Gene
mRNA differential expression in normal tissues according to GTEx for ERICH4 Gene
This gene is overexpressed in Small Intestine - Terminal Ileum (x13.4) and Kidney - Cortex (x12.2).
NURSA nuclear receptor signaling pathways regulating expression of ERICH4 Gene:
ERICH4Primer Products
-
OriGene qPCR primer pairs for ERICH4
- genomics-online: primer clones - Search results for available C19orf69 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ERICH4 Gene
Orthologs for ERICH4 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C19H19orf69 33 |
|
||
| C19orf69 34 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | ERICH4 33 |
|
||
| C19orf69 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | ERICH4 33 |
|
||
| C19orf69 34 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | LOC685046 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Gm7092 34 33 |
|
OneToOne | |
| Erich4 16 |
|
- Species where no ortholog for ERICH4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for ERICH4 Gene
- ENSEMBL:
- Gene Tree for ERICH4 (if available)
- TreeFam:
- Gene Tree for ERICH4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ERICH4: view image
Paralogs for ERICH4 Gene
No data available for Paralogs for ERICH4 Gene
Variants for ERICH4 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000057048 | -- | 41,443,154(+) | C/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant | |
| rs1001058310 | -- | 41,444,151(+) | A/G | coding_sequence_variant, missense_variant | |
| rs1001221550 | -- | 41,441,427(+) | C/G | upstream_transcript_variant | |
| rs1001405850 | -- | 41,444,571(+) | G/A | 3_prime_UTR_variant | |
| rs1001569491 | -- | 41,441,599(+) | G/T | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3644380 | CNV | loss | 21293372 |
Gene Damage Index Score:
3.09;
50.92% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ERICH4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ERICH4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERICH4 Gene
Disorders for ERICH4 Gene
Additional Disease Information for ERICH4
No disorders were found for ERICH4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ERICH4 Gene
Publications for ERICH4 Gene
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
Products for ERICH4 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ERICH4
- Search Origene for MassSpec and Protein Over-expression Lysates for ERICH4
- Origene Custom Protein Services for ERICH4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERICH4
- Browse OriGene Inhibitory RNA Products For ERICH4
- OriGene qPCR primer pairs for ERICH4
- OriGene CRISPR knockouts for ERICH4
- OriGene ORF clones in human for ERICH4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ERICH4
- GenScript: Next-day shipping of latest version cDNA ORF clones for ERICH4 in any vector
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- GenScript Custom Assay Services for ERICH4
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- Browse GenScript CRISPR for ERICH4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ERICH4
- Sino Biological Human cDNA Clone for ERICH4
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ERICH4
- Novus Biologicals proteins for ERICH4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for ERICH4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ERICH4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for ERICH4
- Search GeneTex for Proteins for ERICH4
- Horizon Cell Lines for ERICH4
- genomics-online: cdna clones - Search results for available C19orf69 gene related products
- orf clones - Search results for available C19orf69 gene related products
- genomics-online: gRNA clones - Search results for available C19orf69 gene related products
- genomics-online: primer clones - Search results for available C19orf69 gene related products
- genomics-online: shRNA clones - Search results for available C19orf69 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERICH4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERICH4
- GeneCopoeia miRNA 3'UTR Target clone products for ERICH4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4
Sources for ERICH4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt