Aliases for ERICH4 Gene

Aliases for ERICH4 Gene

  • Glutamate Rich 4 2 3 5
  • Glutamate-Rich Protein 4 3 4
  • C19orf69 3 4
  • Chromosome 19 Open Reading Frame 69 2
  • Glutamate-Rich 4 2
  • LOC100170765 2
  • ERICH4 5

External Ids for ERICH4 Gene

Previous HGNC Symbols for ERICH4 Gene

  • C19orf69

Previous GeneCards Identifiers for ERICH4 Gene

  • GC19P041950

Summaries for ERICH4 Gene

GeneCards Summary for ERICH4 Gene

ERICH4 (Glutamate Rich 4) is a Protein Coding gene.

Additional gene information for ERICH4 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ERICH4 Gene

Genomics for ERICH4 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ERICH4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ERICH4 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ERICH4

Genomic Locations for ERICH4 Gene

Genomic Locations for ERICH4 Gene
2,340 bases
Plus strand
1,608 bases
Plus strand

Genomic View for ERICH4 Gene

Genes around ERICH4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ERICH4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ERICH4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ERICH4 Gene

Proteins for ERICH4 Gene

  • Protein details for ERICH4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glutamate-rich protein 4
    Protein Accession:

    Protein attributes for ERICH4 Gene

    130 amino acids
    Molecular mass:
    14477 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ERICH4 Gene

Post-translational modifications for ERICH4 Gene

No Post-translational modifications

Other Protein References for ERICH4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ERICH4 Gene

Domains & Families for ERICH4 Gene

Gene Families for ERICH4 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ERICH4 Gene

genes like me logo Genes that share domains with ERICH4: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ERICH4 Gene

Function for ERICH4 Gene

Phenotypes From GWAS Catalog for ERICH4 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ERICH4 Gene

Localization for ERICH4 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ERICH4 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ERICH4 Gene

Pathways & Interactions for ERICH4 Gene

PathCards logo

SuperPathways for ERICH4 Gene

No Data Available

Interacting Proteins for ERICH4 Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: A6NGS2-ERIC4_HUMAN ENSP00000367429 for ERICH4 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for ERICH4 Gene


No data available for Pathways by source and SIGNOR curated interactions for ERICH4 Gene

Drugs & Compounds for ERICH4 Gene

No Compound Related Data Available

Transcripts for ERICH4 Gene

mRNA/cDNA for ERICH4 Gene

1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERICH4

Alternative Splicing Database (ASD) splice patterns (SP) for ERICH4 Gene

No ASD Table

Relevant External Links for ERICH4 Gene

GeneLoc Exon Structure for

Expression for ERICH4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ERICH4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ERICH4 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x13.4) and Kidney - Cortex (x12.2).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ERICH4

genes like me logo Genes that share expression patterns with ERICH4: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ERICH4 Gene

Orthologs for ERICH4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ERICH4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C19H19orf69 30
  • 99.67 (n)
C19orf69 31
  • 96 (a)
(Canis familiaris)
Mammalia ERICH4 30
  • 80.51 (n)
C19orf69 31
  • 70 (a)
(Bos Taurus)
Mammalia ERICH4 30
  • 77.18 (n)
C19orf69 31
  • 70 (a)
(Rattus norvegicus)
Mammalia LOC685046 30
  • 74.62 (n)
(Mus musculus)
Mammalia Gm7092 30 31
  • 74.1 (n)
Erich4 17
Species where no ortholog for ERICH4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ERICH4 Gene

Gene Tree for ERICH4 (if available)
Gene Tree for ERICH4 (if available)
Evolutionary constrained regions (ECRs) for ERICH4: view image

Paralogs for ERICH4 Gene

No data available for Paralogs for ERICH4 Gene

Variants for ERICH4 Gene

Additional dbSNP identifiers (rs#s) for ERICH4 Gene

Structural Variations from Database of Genomic Variants (DGV) for ERICH4 Gene

Variant ID Type Subtype PubMed ID
esv3644380 CNV loss 21293372

Variation tolerance for ERICH4 Gene

Gene Damage Index Score: 3.09; 50.92% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ERICH4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ERICH4 Gene

Disorders for ERICH4 Gene

No disorders were found for ERICH4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ERICH4 Gene

Publications for ERICH4 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4
  2. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3

Products for ERICH4 Gene

Sources for ERICH4 Gene