Aliases for ERI1 Gene
Aliases for ERI1 Gene
- Exoribonuclease 1 2 2 3 5
- Histone MRNA 3-End-Specific Exoribonuclease 3 4
- Three Prime Histone MRNA Exonuclease 1 2 3
- Histone MRNA 3-Exonuclease 1 3 4
- 3-5 Exonuclease ERI1 3 4
- THEX1 3 4
- HEXO 3 4
- Enhanced RNAi Three Prime MRNA Exonuclease Homolog 1 (C.Elegans) 2
- Enhanced RNAi Three Prime MRNA Exonuclease Homolog 1 3
- Histone MRNA 3 End-Specific Exonuclease 3
External Ids for ERI1 Gene
- HGNC: 23994
- Entrez Gene: 90459
- Ensembl: ENSG00000104626
- OMIM: 608739
- UniProtKB: Q8IV48
Previous HGNC Symbols for ERI1 Gene
- THEX1
Previous GeneCards Identifiers for ERI1 Gene
- GC08P008900
- GC08P007785
Summaries for ERI1 Gene
GeneCards Summary for ERI1 Gene
ERI1 (Exoribonuclease 1) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Translational Control. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and ribosome binding. An important paralog of this gene is ERI2.
UniProtKB/Swiss-Prot for ERI1 Gene
-
RNA exonuclease that binds to the 3-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2 and 3-hydroxyl groups at the last nucleotide of the histone 3-end is required for efficient degradation of RNA substrates. Also able to degrade the 3-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5-ACCCA-3 sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Additional gene information for ERI1 Gene
- Monarch Initiative
- Search for ERI1 at DataMed
- Search for ERI1 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERI1 Gene
Genomics for ERI1 Gene
GeneHancer (GH) Regulatory Elements for ERI1 Gene
Promoters and enhancers for ERI1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ERI1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ERI1 gene promoter:
-
- CRE-BP1
- ATF-2
- Pax-2b
- Pax-2a
- Pax-2
- RORalpha1
- POU6F1 (c2)
- Ik-1
- HNF-3beta
- c-Ets-1
Regulatory Element Products
Genomic Locations for ERI1 Gene
Genomic Locations for ERI1 Gene
- chr8:9,002,147-9,116,746
- (GRCh38/hg38)
- Size:
- 114,600 bases
- Orientation:
- Plus strand
- chr8:8,859,657-8,974,256
- (GRCh37/hg19)
- Size:
- 114,600 bases
- Orientation:
- Plus strand
Genomic View for ERI1 Gene
Genes around ERI1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p23.1 by Entrez Gene
- 8p23.1 by HGNC
- 8p23.1 by Ensembl
ERI1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ERI1 Gene
Proteins for ERI1 Gene
-
Protein details for ERI1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IV48-ERI1_HUMAN
- Recommended name:
- 3-5 exoribonuclease 1
- Protein Accession:
- Q8IV48
- A8K4U7
- Q9NSX3
Protein attributes for ERI1 Gene
- Size:
- 349 amino acids
- Molecular mass:
- 40064 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Identified in a histone pre-mRNA complex, at least composed of ERI1, LSM11, SLBP, SNRPB, SYNCRIP and YBX1. Interacts in a cooperative manner with SLBP to the mature 3-end of histone mRNAs (By similarity). Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Found in a ternary complex with SLBP and the stem-loop structure of the 3-end of histone mRNAs.
- SequenceCaution:
-
- Sequence=CAB70871.2; Type=Erroneous termination; Positions=159; Note=Translated as Leu.; Evidence={ECO:0000305}; Sequence=CAB70871.2; Type=Frameshift; Positions=117; Evidence={ECO:0000305};
Protein Expression for ERI1 Gene
Post-translational modifications for ERI1 Gene
Other Protein References for ERI1 Gene
Antibody Products
- Novus Biologicals Antibodies for ERI1
- Invitrogen Antibodies for ERI1
- GeneTex ERI1 Antibody for ERI1
-
Boster Bio Antibodies for ERI1
-
Santa Cruz Biotechnology (SCBT) Antibodies for ERI1
Protein Products
-
OriGene Purified Proteins for ERI1
- Search Origene for MassSpec and Protein Over-expression Lysates for ERI1
- Origene Custom Protein Services for ERI1
- Search GeneTex for Proteins for ERI1
-
Abcam proteins for ERI1
Assay Products
- antibodies-online: Search results for available ERI1 related products ranked by validation data
No data available for DME Specific Peptides for ERI1 Gene
Domains & Families for ERI1 Gene
Gene Families for ERI1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ERI1 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ERI1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IV48UniProtKB/Swiss-Prot:
ERI1_HUMAN :- The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3-end histone mRNA exonuclease activity.
- Domain:
-
- The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3-end histone mRNA exonuclease activity.
Function for ERI1 Gene
Molecular function for ERI1 Gene
- UniProtKB/Swiss-Prot Function:
- RNA exonuclease that binds to the 3-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2 and 3-hydroxyl groups at the last nucleotide of the histone 3-end is required for efficient degradation of RNA substrates. Also able to degrade the 3-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5-ACCCA-3 sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Although it can bind simultaneously with SLBP to the 3-end of histone mRNA, the presence of SLBP prevents the exonuclease activity.
Enzyme Numbers (IUBMB) for ERI1 Gene
Phenotypes From GWAS Catalog for ERI1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000175 | 3-5-exoribonuclease activity | TAS | -- |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IEA | -- |
| GO:0004518 | nuclease activity | IEA | -- |
| GO:0004527 | exonuclease activity | IEA | -- |
Phenotypes for ERI1 Gene
- MGI mutant phenotypes for ERI1:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for ERI1:
Animal Models for ERI1 Gene
- MGI Knock Outs for ERI1:
-
- Eri1 Eri1<tm1.2Anse>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ERI1
-
CRISPR Products
-
OriGene CRISPR knockouts for ERI1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERI1
- genomics-online: gRNA clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- Applied Biological Materials CRISPR for ERI1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERI1
- GenScript: Design CRISPR guide RNA sequences for ERI1
miRNA for ERI1 Gene
- miRTarBase miRNAs that target ERI1
-
- hsa-mir-155-5p (MIRT020545)
- hsa-mir-30c-5p (MIRT047993)
- hsa-mir-548p (MIRT402602)
- hsa-mir-1277-5p (MIRT447885)
- hsa-mir-6507-5p (MIRT447886)
- hsa-mir-186-5p (MIRT447888)
- hsa-mir-208a-3p (MIRT537616)
- hsa-mir-6888-3p (MIRT537617)
- hsa-mir-3120-5p (MIRT537618)
- hsa-mir-6868-5p (MIRT537619)
- hsa-mir-372-5p (MIRT537620)
- hsa-mir-371a-5p (MIRT537621)
- hsa-mir-616-5p (MIRT537622)
- hsa-mir-373-5p (MIRT537623)
- hsa-mir-371b-5p (MIRT537624)
- hsa-mir-8073 (MIRT537625)
- hsa-mir-221-5p (MIRT537626)
- hsa-mir-3664-5p (MIRT537627)
- hsa-mir-548x-3p (MIRT537628)
- hsa-mir-548j-3p (MIRT537629)
- hsa-mir-548aq-3p (MIRT537630)
- hsa-mir-548am-3p (MIRT537631)
- hsa-mir-548aj-3p (MIRT537632)
- hsa-mir-548ah-3p (MIRT537633)
- hsa-mir-548ae-3p (MIRT537634)
- hsa-mir-6738-3p (MIRT650234)
- hsa-mir-544a (MIRT650235)
- hsa-mir-4724-3p (MIRT650236)
- hsa-mir-20a-3p (MIRT650237)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERI1
- Browse OriGene Inhibitory RNA Products For ERI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERI1
- genomics-online: shRNA clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ERI1
- VectorBuilder custom plasmid, inducible vectors for ERI1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ERI1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERI1
- Applied Biological Materials Clones for ERI1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ERI1
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ERI1 Gene
Localization for ERI1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ERI1 Gene
- Cytoplasm. Nucleus. Nucleus, nucleolus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| cytosol | 1 |
- Microtubules (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | ISS | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | nucleolus | ISS | -- |
| GO:0005737 | cytoplasm | ISS | -- |
| GO:0071204 | histone pre-mRNA 3end processing complex | ISS | -- |
Pathways & Interactions for ERI1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | rRNA processing in the nucleus and cytosol |
.89
|
|
| 2 | Chromatin Regulation / Acetylation | ||
| 3 | Translational Control | ||
| 4 | Gene Expression |
.48
|
|
| 5 | DDX1 as a regulatory component of the Drosha microprocessor |
.33
|
|
Pathways by source for ERI1 Gene
1 BioSystems pathway for ERI1 Gene
4 Reactome pathways for ERI1 Gene
2 Cell Signaling Technology pathways for ERI1 Gene
Interacting Proteins for ERI1 Gene
Selected Interacting proteins:
Q8IV48-ERI1_HUMAN
ENSP00000250263
for ERI1 Gene via
IID
STRING
UniProtKB
GPS-Prot Interaction Network for ERI1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000467 | exonucleolytic trimming to generate mature 3-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IBA | -- |
| GO:0000738 | DNA catabolic process, exonucleolytic | IBA | -- |
| GO:0006259 | DNA metabolic process | IBA | -- |
| GO:0006364 | rRNA processing | TAS | -- |
| GO:0031047 | gene silencing by RNA | IEA | -- |
No data available for SIGNOR curated interactions for ERI1 Gene
Drugs & Compounds for ERI1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Magnesium | Approved | Nutra | 0 |
Transcripts for ERI1 Gene
mRNA/cDNA for ERI1 Gene
- (12) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (154) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000523898 5036 bps (uc064kcn.1)
- ENST00000519292 2107 bps (uc033bbm.2)
- ENST00000521844 557 bps (uc064kco.1)
- ENST00000520684 828 bps (uc064kcp.1)
- ENST00000520332 750 bps (uc064kcq.1)
CRISPR Products
-
OriGene CRISPR knockouts for ERI1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERI1
- genomics-online: gRNA clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- Applied Biological Materials CRISPR for ERI1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERI1
- GenScript: Design CRISPR guide RNA sequences for ERI1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERI1
- Browse OriGene Inhibitory RNA Products For ERI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERI1
- genomics-online: shRNA clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ERI1
- VectorBuilder custom plasmid, inducible vectors for ERI1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ERI1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERI1
- Applied Biological Materials Clones for ERI1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: |
Expression for ERI1 Gene
This gene is overexpressed in Lung (53.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ERI1 Gene
NURSA nuclear receptor signaling pathways regulating expression of ERI1 Gene:
ERI1SOURCE GeneReport for Unigene cluster for ERI1 Gene:
Hs.20000Primer Products
-
OriGene qPCR primer pairs and template standards for ERI1
-
OriGene qPCR primer pairs for ERI1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ERI1 Gene
Orthologs for ERI1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ERI1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | THEX1 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| ERI1 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | ERI1 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Eri1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Eri1 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ERI1 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ERI1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ERI1 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ERI1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | eri1 33 |
|
||
| Str.6568 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.8018 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | eri1 34 33 |
|
OneToOne | |
| Dr.15106 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.6758 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | eri-1 34 33 |
|
ManyToMany | |
| crn-4 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | eri1 33 |
|
- Species where no ortholog for ERI1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for ERI1 Gene
- ENSEMBL:
- Gene Tree for ERI1 (if available)
- TreeFam:
- Gene Tree for ERI1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ERI1: view image
Paralogs for ERI1 Gene
Variants for ERI1 Gene
| SNP ID | Clin | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000015182 | -- | 8,915,090(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000020953 | -- | 9,000,209(+) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000030615 | -- | 9,011,298(+) | G/C | intron_variant | |
| rs1000046886 | -- | 8,999,586(+) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000084605 | -- | 9,068,595(+) | C/G | genic_downstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv831229 | CNV | gain+loss | 17160897 |
| nsv610205 | CNV | loss | 21841781 |
| nsv1075109 | CNV | deletion | 25765185 |
| esv3616162 | CNV | loss | 21293372 |
| esv3616157 | CNV | loss | 21293372 |
Residual Variation Intolerance Score:
17% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.80;
33.91% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ERI1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ERI1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERI1 Gene
Disorders for ERI1 Gene
Additional Disease Information for ERI1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for ERI1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ERI1 Gene
Publications for ERI1 Gene
- Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA. (PMID: 16912046) Yang XC … Dominski Z (The Journal of biological chemistry 2006) 3 4 22 58
- Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP. (PMID: 15451662) Cheng Y … Patel DJ (Journal of molecular biology 2004) 3 4 22 58
- A 3' exonuclease that specifically interacts with the 3' end of histone mRNA. (PMID: 14536070) Dominski Z … Marzluff WF (Molecular cell 2003) 2 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for ERI1 Gene
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- Abcam proteins for ERI1
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- Cyagen custom Knockout/knockin (KOKI) mouse models for ERI1
- VectorBuilder custom plasmid, inducible vectors for ERI1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ERI1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 63 available ERI1 Antibodies ranked by validation data
- Compare Top ERI1 Antibodies
- antibodies-online: Search results for available ERI1 related products ranked by validation data
- antibodies-online: Search results for 8 available ERI1 Proteins ranked by validation data
- Compare Top ERI1 Proteins
- Quality Products:
- GeneTex ERI1 Antibody for ERI1
- Search GeneTex for Proteins for ERI1
- Santa Cruz Biotechnology (SCBT) Antibodies for ERI1
- Search Santa Cruz Biotechnology (SCBT) for ERI1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ERI1
- Horizon Cell Lines for ERI1
- genomics-online: cdna clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- orf clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- genomics-online: gRNA clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- genomics-online: primer clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- genomics-online: shRNA clones - Search results for 94 available ERI1 gene related products
- Overview of 94 available ERI1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERI1
- GeneCopoeia miRNA 3'UTR Target clone products for ERI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERI1
- Boster Bio Antibodies for ERI1
- Browse Boster Bio ELISA Kits
Sources for ERI1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt