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Aliases for ERI1 Gene
Aliases for ERI1 Gene
External Ids for ERI1 Gene
- HGNC: 23994
- Entrez Gene: 90459
- Ensembl: ENSG00000104626
- OMIM: 608739
- UniProtKB: Q8IV48
Previous HGNC Symbols for ERI1 Gene
- THEX1
Previous GeneCards Identifiers for ERI1 Gene
- GC08P008900
- GC08P007785
- GC08P009002
Summaries for ERI1 Gene
GeneCards Summary for ERI1 Gene
ERI1 (Exoribonuclease 1) is a Protein Coding gene. Diseases associated with ERI1 include Locked-In Syndrome and Retinitis Pigmentosa 7. Among its related pathways are rRNA processing in the nucleus and cytosol and DDX1 as a regulatory component of the Drosha microprocessor. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and ribosome binding. An important paralog of this gene is ERI3.
UniProtKB/Swiss-Prot Summary for ERI1 Gene
-
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Additional gene information for ERI1 Gene
- HGNC(23994)
- Entrez Gene(90459)
- Ensembl(ENSG00000104626)
- OMIM(608739)
- UniProtKB(Q8IV48)
- Open Targets Platform(ENSG00000104626)
- Monarch Initiative
- Search for ERI1 at DataMed
- Search for ERI1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ERI1 Gene
Genomics for ERI1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ERI1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ERI1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ERI1
- Top Transcription factor binding sites by QIAGEN in the ERI1 gene promoter:
-
- ATF-2
- c-Ets-1
- CRE-BP1
- HNF-3beta
- Ik-1
- Pax-2
- Pax-2a
- Pax-2b
- POU6F1 (c2)
- RORalpha1
Genomic Locations for ERI1 Gene
Genomic Locations for ERI1 Gene
- chr8:8,892,225-9,116,746
- (GRCh38/hg38)
- Size:
- 224,522 bases
- Orientation:
- Plus strand
- chr8:8,859,657-8,974,256
- (GRCh37/hg19)
- Size:
- 114,600 bases
- Orientation:
- Plus strand
Genomic View for ERI1 Gene
Genes around ERI1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p23.1 by HGNC
- 8p23.1 by Entrez Gene
- 8p23.1 by Ensembl
ERI1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ERI1 Gene
Proteins for ERI1 Gene
-
Protein details for ERI1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IV48-ERI1_HUMAN
- Recommended name:
- 3'-5' exoribonuclease 1
- Protein Accession:
- Q8IV48
- A8K4U7
- Q9NSX3
Protein attributes for ERI1 Gene
- Size:
- 349 amino acids
- Molecular mass:
- 40064 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Identified in a histone pre-mRNA complex, at least composed of ERI1, LSM11, SLBP, SNRPB, SYNCRIP and YBX1. Interacts in a cooperative manner with SLBP to the mature 3'-end of histone mRNAs (By similarity). Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Found in a ternary complex with SLBP and the stem-loop structure of the 3'-end of histone mRNAs.
- SequenceCaution:
-
- Sequence=CAB70871.2; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305}; Sequence=CAB70871.2; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for ERI1 Gene
Post-translational modifications for ERI1 Gene
Other Protein References for ERI1 Gene
Antibody Products
- G Biosciences Immunotag™ ERI1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for ERI1
- Novus Biologicals Antibodies for ERI1
- Invitrogen Antibodies for ERI1 (AFLGC-ERI1)
-
Santa Cruz Biotechnology (SCBT) Antibodies for ERI1
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for ERI1
- Origene Custom Protein Services for ERI1
- antibodies-online: Show 10 available ERI1 Proteins ranked by validation data
- Compare Top ERI1 Proteins
-
Quality Products:
-
Abcam proteins for ERI1
Assay Products
- antibodies-online: Show 6 available ERI1 Elisa Kits ranked by validation data
- Compare Top ERI1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for ERI1 Gene
Domains & Families for ERI1 Gene
Gene Families for ERI1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ERI1 Gene
- InterPro:
- Blocks:
-
- Exonuclease
- DNA-binding SAP
- ProtoNet:
Suggested Antigen Peptide Sequences for ERI1 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein 3'hExo (ERI1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8IV48UniProtKB/Swiss-Prot:
ERI1_HUMAN :- The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3'-end histone mRNA exonuclease activity.
- Domain:
-
- The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3'-end histone mRNA exonuclease activity.
Function for ERI1 Gene
Molecular function for ERI1 Gene
- UniProtKB/Swiss-Prot Function:
- RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBP prevents the exonuclease activity.
Enzyme Numbers (IUBMB) for ERI1 Gene
Phenotypes From GWAS Catalog for ERI1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000175 | 3'-5'-exoribonuclease activity | TAS | -- |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IEA | -- |
| GO:0004518 | nuclease activity | IEA | -- |
| GO:0004527 | exonuclease activity | IEA | -- |
Phenotypes for ERI1 Gene
- MGI mutant phenotypes for ERI1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ERI1:
Animal Models for ERI1 Gene
- MGI Knock Outs for ERI1:
-
- Eri1 Eri1<tm1.2Anse>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ERI1 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for ERI1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERI1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERI1
miRNA for ERI1 Gene
- miRTarBase miRNAs that target ERI1
-
- mmu-miR-124-3p (MIRT015777)
- hsa-miR-155-5p (MIRT020545)
- hsa-miR-30c-5p (MIRT047993)
- hsa-miR-548p (MIRT402602)
- hsa-miR-1277-5p (MIRT447885)
- hsa-miR-6507-5p (MIRT447886)
- hsa-miR-186-5p (MIRT447888)
- hsa-miR-208a-3p (MIRT537616)
- hsa-miR-6888-3p (MIRT537617)
- hsa-miR-3120-5p (MIRT537618)
- hsa-miR-6868-5p (MIRT537619)
- hsa-miR-372-5p (MIRT537620)
- hsa-miR-371a-5p (MIRT537621)
- hsa-miR-616-5p (MIRT537622)
- hsa-miR-373-5p (MIRT537623)
- hsa-miR-371b-5p (MIRT537624)
- hsa-miR-8073 (MIRT537625)
- hsa-miR-221-5p (MIRT537626)
- hsa-miR-3664-5p (MIRT537627)
- hsa-miR-548x-3p (MIRT537628)
- hsa-miR-548j-3p (MIRT537629)
- hsa-miR-548aq-3p (MIRT537630)
- hsa-miR-548am-3p (MIRT537631)
- hsa-miR-548aj-3p (MIRT537632)
- hsa-miR-548ah-3p (MIRT537633)
- hsa-miR-548ae-3p (MIRT537634)
- hsa-miR-6738-3p (MIRT650234)
- hsa-miR-544a (MIRT650235)
- hsa-miR-4724-3p (MIRT650236)
- hsa-miR-20a-3p (MIRT650237)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERI1
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERI1
Clone Products
- Applied Biological Materials (abm): Clones for ERI1 - Select products 50% OFF >
- * ERI1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ERI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERI1
Cell Line Products
-
Horizon Cell Lines for ERI1
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ERI1 Gene
Localization for ERI1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ERI1 Gene
- Cytoplasm. Nucleus. Nucleus, nucleolus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 3 |
| extracellular | 2 |
| mitochondrion | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
- Microtubules (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | ISS | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | nucleolus | IBA,ISS | -- |
| GO:0005737 | cytoplasm | IBA,ISS | -- |
| GO:0071204 | histone pre-mRNA 3'end processing complex | ISS | -- |
Pathways & Interactions for ERI1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | rRNA processing in the nucleus and cytosol |
.89
|
|
| 2 | Chromatin Regulation / Acetylation | ||
| 3 | Translational Control | ||
| 4 | Gene Expression |
.48
|
|
| 5 | DDX1 as a regulatory component of the Drosha microprocessor |
.33
|
|
Pathways by source for ERI1 Gene
1 BioSystems pathway for ERI1 Gene
4 Reactome pathways for ERI1 Gene
2 Cell Signaling Technology pathways for ERI1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000467 | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IBA | 21873635 |
| GO:0000738 | DNA catabolic process, exonucleolytic | IBA | 21873635 |
| GO:0006259 | DNA metabolic process | IBA | 21873635 |
| GO:0006364 | rRNA processing | TAS | -- |
| GO:0031047 | gene silencing by RNA | IEA | -- |
No data available for SIGNOR curated interactions for ERI1 Gene
Drugs & Compounds for ERI1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Magnesium | Approved, Experimental, Investigational | Pharma | 0 |
Transcripts for ERI1 Gene
mRNA/cDNA for ERI1 Gene
- 4 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000250263 4521 nts (view in UCSC)
- ENST00000518663 698 nts (view in UCSC)
- ENST00000519292 2107 nts (view in UCSC)
- ENST00000520332 750 nts (view in UCSC)
- ENST00000520684 828 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ERI1 - Select products 50% OFF >
- * ERI1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ERI1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERI1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ERI1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ERI1
- Browse OriGene Inhibitory RNA Products For ERI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERI1
Clone Products
- Applied Biological Materials (abm): Clones for ERI1 - Select products 50% OFF >
- * ERI1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ERI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERI1
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: |
Relevant External Links for ERI1 Gene
- GeneLoc Exon Structure for
- ERI1
Expression for ERI1 Gene
This gene is overexpressed in Lung (53.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ERI1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ERI1
SOURCE GeneReport for Unigene cluster for ERI1 Gene:
Hs.20000Evidence on tissue expression from TISSUES for ERI1 Gene
- Nervous system(2.4)
- Skin(2.1)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs for ERI1
-
OriGene qPCR primer pairs and template standards for ERI1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ERI1 Gene
Orthologs for ERI1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ERI1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | THEX1 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| ERI1 30 |
|
||||
| Dog (Canis familiaris) |
Mammalia | ERI1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Eri1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Eri1 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ERI1 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ERI1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ERI1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ERI1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | eri1 30 |
|
||
| Str.6568 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.8018 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | eri1 30 31 |
|
OneToOne | |
| Dr.15106 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.6758 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | eri-1 30 31 |
|
ManyToMany | |
| crn-4 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne | |
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | eri1 30 |
|
- Species where no ortholog for ERI1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ERI1 Gene
- ENSEMBL:
- Gene Tree for ERI1 (if available)
- TreeFam:
- Gene Tree for ERI1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ERI1: view image
Paralogs for ERI1 Gene
Variants for ERI1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ERI1 Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 712692 | Likely Benign: not provided | 9,007,961(+) | T/G | INTRON_VARIANT | |
| 715007 | Benign: not provided | 8,892,426(+) | C/T | SYNONYMOUS_VARIANT | |
| 731735 | Likely Benign: not provided | 9,007,961(+) | T/TTG | INTRON_VARIANT | |
| 752712 | Likely Benign: not provided | 8,892,708(+) | G/A | SYNONYMOUS_VARIANT | |
| 768227 | Benign: not provided | 9,029,857(+) | G/C | SYNONYMOUS_VARIANT,INTRON_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3616157 | CNV | loss | 21293372 |
| esv3616162 | CNV | loss | 21293372 |
| nsv1075109 | CNV | deletion | 25765185 |
| nsv610205 | CNV | loss | 21841781 |
| nsv831229 | CNV | gain+loss | 17160897 |
Residual Variation Intolerance Score:
17% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.80;
33.91% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ERI1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ERI1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERI1 Gene
Disorders for ERI1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| locked-in syndrome |
|
|
| retinitis pigmentosa 7 |
|
|
Search ERI1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ERI1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ERI1 Gene
Publications for ERI1 Gene
- Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA. (PMID: 16912046) Yang XC … Dominski Z (The Journal of biological chemistry 2006) 3 4 23
- Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP. (PMID: 15451662) Cheng Y … Patel DJ (Journal of molecular biology 2004) 3 4 23
- A 3' exonuclease that specifically interacts with the 3' end of histone mRNA. (PMID: 14536070) Dominski Z … Marzluff WF (Molecular cell 2003) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for ERI1 Gene
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- High-throughput Antibody Production Service
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- Invitrogen Antibodies for ERI1 (AFLGC-ERI1)
- VectorBuilder Custom and pre-made DNA vectors for ERI1 (ie. gene expression, shRNA knockdown, CRISPR)
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- VectorBuilder Stable cell line generation for ERI1
- antibodies-online: Show 41 available ERI1 Antibodies ranked by validation data
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- Quality Products:
- antibodies-online: Show 10 available ERI1 Proteins ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for ERI1
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- Santa Cruz Biotechnology (SCBT) CRISPR for ERI1
- Horizon Cell Lines for ERI1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ERI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ERI1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ERI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ERI1
Sources for ERI1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB