Free for academic non-profit institutions. Other users need a Commercial license
ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]
ERGIC2 (ERGIC And Golgi 2) is a Protein Coding gene. Diseases associated with ERGIC2 include Acute Maxillary Sinusitis and Temtamy Syndrome. An important paralog of this gene is ERGIC3.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 17980171 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 17980171 |
GO:0005730 | nucleolus | IDA | -- |
GO:0005737 | cytoplasm | IEA,IDA | 17980171 |
GO:0005783 | endoplasmic reticulum | IBA | 21873635 |
GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006888 | ER to Golgi vesicle-mediated transport | IBA | 21873635 |
GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | IMP | 24768165 |
GO:0016192 | vesicle-mediated transport | IEA | -- |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||
SP3: | - | - |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ERGIC2 30 |
|
||
Dog (Canis familiaris) |
Mammalia | ERGIC2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ERGIC2 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Ergic2 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | ERGIC2 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | ERGIC2 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | ERGIC2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ERGIC2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ergic2 30 |
|
||
MGC75899 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.16162 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | ergic2 30 31 |
|
OneToMany | |
ERGIC2 (1 of 2) 31 |
|
OneToMany | |||
zgc64005 30 |
|
||||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3142 30 |
|
||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005044 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG4293 30 31 |
|
OneToOne | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ERV41 30 |
|
||
ERV46 31 |
|
OneToMany | |||
K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0B04950g 30 |
|
||
A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AER136W 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.3984 31 |
|
OneToOne | |
Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPBC2G5.04c 30 |
|
||
Bread mold (Neurospora crassa) |
Ascomycetes | NCU04293 30 |
|
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3344998 | CNV | insertion | 20981092 |
Disorder | Aliases | PubMed IDs |
---|---|---|
acute maxillary sinusitis |
|
|
temtamy syndrome |
|
|
cantu syndrome |
|
|