Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ERCC8 Gene

Aliases for ERCC8 Gene

  • ERCC Excision Repair 8, CSA Ubiquitin Ligase Complex Subunit 2 3 5
  • Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 2 3
  • Excision Repair Cross-Complementation Group 8 2 3
  • Cockayne Syndrome WD Repeat Protein CSA 3 4
  • CKN1 3 4
  • CSA 3 4
  • Cockayne Syndrome WD-Repeat Protein CSA 3
  • DNA Excision Repair Protein ERCC-8 3
  • Cockayne Syndrome 1 (Classical) 2
  • UVSS2 3

External Ids for ERCC8 Gene

Previous HGNC Symbols for ERCC8 Gene

  • CKN1

Previous GeneCards Identifiers for ERCC8 Gene

  • GC00U990095
  • GC05M060206
  • GC05M060169
  • GC05M057127

Summaries for ERCC8 Gene

Entrez Gene Summary for ERCC8 Gene

  • This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]

GeneCards Summary for ERCC8 Gene

ERCC8 (ERCC Excision Repair 8, CSA Ubiquitin Ligase Complex Subunit) is a Protein Coding gene. Diseases associated with ERCC8 include Uv-Sensitive Syndrome 2 and Cockayne Syndrome A. Among its related pathways are Transcription-Coupled Nucleotide Excision Repair (TC-NER) and Nucleotide excision repair. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity and DNA-dependent ATPase activity.

UniProtKB/Swiss-Prot for ERCC8 Gene

  • Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.

Gene Wiki entry for ERCC8 Gene

Additional gene information for ERCC8 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERCC8 Gene

Genomics for ERCC8 Gene

GeneHancer (GH) Regulatory Elements for ERCC8 Gene

Promoters and enhancers for ERCC8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I060943 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 563 +0.1 50 3.2 HDGF PKNOX1 ARID4B SIN3A ZNF2 YY1 POLR2B ZNF766 ZNF548 FOS ERCC8 NDUFAF2 ZSWIM6 ELOVL7 LOC105378991
GH05I061327 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.2 -386.5 -386501 7.9 PKNOX1 FOXA2 ARID4B SIN3A FEZF1 ZNF2 IRF4 YY1 ZNF213 ZNF143 ZSWIM6 LOC105378994 NDUFAF2 ERCC8 ELOVL7 LOC105378993
GH05I060842 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 12.5 +101.0 101010 2.4 ATF1 ZFP64 ARID4B SIN3A ZNF2 ZNF121 GLIS2 ZNF143 FOS ATF7 ELOVL7 ERCC8 NDUFAF2 KRT8P31
GH05I061161 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.3 -217.6 -217555 2.9 HDGF FOXA2 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B E2F8 ZNF207 SMIM15 SMIM15-AS1 ERCC8 ELOVL7 NDUFAF2 GC05P061168
GH05I060820 Enhancer 0.9 ENCODE 13.3 +124.0 124040 2 HDGF PKNOX1 ATF1 ARNT NCOA2 TCF12 E2F8 ATF7 CAVIN1 NCOA1 ELOVL7 ERCC8 KRT8P31
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ERCC8 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ERCC8 gene promoter:

Genomic Locations for ERCC8 Gene

Genomic Locations for ERCC8 Gene
chr5:60,873,831-60,945,078
(GRCh38/hg38)
Size:
71,248 bases
Orientation:
Minus strand
chr5:60,169,658-60,240,905
(GRCh37/hg19)

Genomic View for ERCC8 Gene

Genes around ERCC8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ERCC8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ERCC8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ERCC8 Gene

Proteins for ERCC8 Gene

  • Protein details for ERCC8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13216-ERCC8_HUMAN
    Recommended name:
    DNA excision repair protein ERCC-8
    Protein Accession:
    Q13216
    Secondary Accessions:
    • B2RB64
    • Q6FHX5
    • Q96GB9

    Protein attributes for ERCC8 Gene

    Size:
    396 amino acids
    Molecular mass:
    44055 Da
    Quaternary structure:
    • Part of the CSA complex (DCX(ERCC8) complex), a DCX E3 ubiquitin-protein ligase complex containing ERCC8, RBX1, DDB1 and CUL4A; the CSA complex interacts with RNA polymerase II; upon UV irradiation it interacts with the COP9 signalosome and preferentially with the hyperphosphorylated form of RNA polymerase II. Interacts with ERCC6 and KIAA1530/UVSSA. Interacts with a subunit of RNA polymerase II TFIIH. Interacts directly with DDB1 (PubMed:22118460).

    Three dimensional structures from OCA and Proteopedia for ERCC8 Gene

    Alternative splice isoforms for ERCC8 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ERCC8 Gene

Post-translational modifications for ERCC8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ERCC8 Gene

No data available for DME Specific Peptides for ERCC8 Gene

Domains & Families for ERCC8 Gene

Gene Families for ERCC8 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ERCC8: view

No data available for UniProtKB/Swiss-Prot for ERCC8 Gene

Function for ERCC8 Gene

Molecular function for ERCC8 Gene

UniProtKB/Swiss-Prot Function:
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.

Phenotypes From GWAS Catalog for ERCC8 Gene

Gene Ontology (GO) - Molecular Function for ERCC8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003678 NOT DNA helicase activity IDA 8999876
GO:0004842 contributes_to ubiquitin-protein transferase activity IDA 12732143
GO:0005515 protein binding IPI 10944529
GO:0008094 NOT DNA-dependent ATPase activity IDA 8999876
GO:0032403 protein complex binding IDA 16916636
genes like me logo Genes that share ontologies with ERCC8: view
genes like me logo Genes that share phenotypes with ERCC8: view

Human Phenotype Ontology for ERCC8 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for ERCC8 Gene

MGI Knock Outs for ERCC8:

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ERCC8 Gene

Localization for ERCC8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ERCC8 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ERCC8 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ERCC8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000109 nucleotide-excision repair complex IDA 12732143
GO:0005634 nucleus IDA 11782547
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm IEA --
GO:0016363 nuclear matrix IDA 11782547
genes like me logo Genes that share ontologies with ERCC8: view

Pathways & Interactions for ERCC8 Gene

genes like me logo Genes that share pathways with ERCC8: view

UniProtKB/Swiss-Prot Q13216-ERCC8_HUMAN

  • Pathway: Protein modification; protein ubiquitination.

Gene Ontology (GO) - Biological Process for ERCC8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination IDA 12732143
GO:0006281 DNA repair IEA --
GO:0006283 transcription-coupled nucleotide-excision repair IDA,TAS --
GO:0006289 nucleotide-excision repair IMP 17297471
GO:0006974 cellular response to DNA damage stimulus IDA,IEA 11782547
genes like me logo Genes that share ontologies with ERCC8: view

No data available for SIGNOR curated interactions for ERCC8 Gene

Drugs & Compounds for ERCC8 Gene

No Compound Related Data Available

Transcripts for ERCC8 Gene

Unigene Clusters for ERCC8 Gene

Excision repair cross-complementing rodent repair deficiency, complementation group 8:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ERCC8 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
SP1: - -
SP2: - - -
SP3: - -
SP4:

Relevant External Links for ERCC8 Gene

GeneLoc Exon Structure for
ERCC8
ECgene alternative splicing isoforms for
ERCC8

Expression for ERCC8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ERCC8 Gene

Protein differential expression in normal tissues from HIPED for ERCC8 Gene

This gene is overexpressed in Adipocyte (29.0), Brain (20.1), and Urinary Bladder (17.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ERCC8 Gene



Protein tissue co-expression partners for ERCC8 Gene

NURSA nuclear receptor signaling pathways regulating expression of ERCC8 Gene:

ERCC8

SOURCE GeneReport for Unigene cluster for ERCC8 Gene:

Hs.435237

Phenotype-based relationships between genes and organs from Gene ORGANizer for ERCC8 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • ear
  • eye
  • face
  • head
  • jaw
  • lacrimal apparatus
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • outer ear
  • pituitary gland
  • skull
  • tooth
Thorax:
  • breast
  • chest wall
  • clavicle
  • heart
  • heart valve
  • rib
  • rib cage
  • scapula
  • sternum
  • thymus
Abdomen:
  • kidney
  • liver
  • spleen
Pelvis:
  • ovary
  • pelvis
  • penis
  • prostate
  • testicle
  • ureter
  • urinary bladder
  • uterus
  • vagina
  • vulva
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • coagulation system
  • hair
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal column
  • spinal cord
  • sweat gland
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with ERCC8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Evidence on tissue expression from TISSUES for ERCC8 Gene

Orthologs for ERCC8 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ERCC8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ERCC8 33 34
  • 99.24 (n)
cow
(Bos Taurus)
Mammalia ERCC8 33 34
  • 93.1 (n)
dog
(Canis familiaris)
Mammalia ERCC8 33 34
  • 92.34 (n)
rat
(Rattus norvegicus)
Mammalia Ercc8 33
  • 86.7 (n)
oppossum
(Monodelphis domestica)
Mammalia ERCC8 34
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ercc8 33 16 34
  • 85.77 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ERCC8 34
  • 84 (a)
OneToOne
chicken
(Gallus gallus)
Aves ERCC8 33 34
  • 81.1 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 79 (a)
OneToMany
-- 34
  • 67 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia ercc8 33
  • 73.48 (n)
Str.20460 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.5566 33
zebrafish
(Danio rerio)
Actinopterygii ercc8 33 34
  • 69.8 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RAD28 34 36
  • 18 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G19750 33
  • 52.87 (n)
rice
(Oryza sativa)
Liliopsida Os01g0857900 33
  • 54.93 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes ckn1 33
  • 46.74 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2623 34
  • 37 (a)
OneToOne
Species where no ortholog for ERCC8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ERCC8 Gene

ENSEMBL:
Gene Tree for ERCC8 (if available)
TreeFam:
Gene Tree for ERCC8 (if available)

Paralogs for ERCC8 Gene

No data available for Paralogs for ERCC8 Gene

Variants for ERCC8 Gene

Sequence variations from dbSNP and Humsavar for ERCC8 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1043679457 pathogenic, Cockayne syndrome type A 60,927,745(-) C/A/G intron_variant
rs121434323 pathogenic, Cockayne syndrome type A 60,890,964(-) G/C/T coding_sequence_variant, genic_downstream_transcript_variant, stop_gained
rs121434324 pathogenic, Cockayne syndrome type A 60,944,972(-) C/A 5_prime_UTR_variant, coding_sequence_variant, stop_gained
rs121434325 pathogenic, likely-pathogenic, Cockayne syndrome type A, not provided, Cockayne syndrome A (CSA) [MIM:216400] 60,904,794(-) G/A coding_sequence_variant, intron_variant, missense_variant
rs121434326 pathogenic, not-provided, Cockayne syndrome type A, not provided, Cockayne syndrome A (CSA) [MIM:216400] 60,902,446(-) C/G coding_sequence_variant, genic_downstream_transcript_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for ERCC8 Gene

Variant ID Type Subtype PubMed ID
dgv9810n54 CNV loss 21841781
dgv9811n54 CNV loss 21841781
esv2673115 CNV deletion 23128226
esv2762523 CNV loss 21179565
esv3605199 CNV loss 21293372
nsv1025896 CNV loss 25217958
nsv1077987 CNV duplication 25765185
nsv1161250 CNV deletion 26073780
nsv1161251 CNV deletion 26073780
nsv462199 CNV gain 19166990
nsv462200 CNV loss 19166990
nsv520871 CNV loss 19592680
nsv598308 CNV gain 21841781

Variation tolerance for ERCC8 Gene

Residual Variation Intolerance Score: 53.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.78; 79.01% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ERCC8 Gene

Human Gene Mutation Database (HGMD)
ERCC8
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ERCC8

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERCC8 Gene

Disorders for ERCC8 Gene

MalaCards: The human disease database

(8) MalaCards diseases for ERCC8 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
uv-sensitive syndrome 2
  • uvss2
cockayne syndrome a
  • csa
cockayne syndrome type i
  • cockayne syndrome classic form
cockayne syndrome type iii
  • cockayne syndrome type 3
cockayne syndrome type ii
  • cockayne syndrome type 2
- elite association - COSMIC cancer census association via MalaCards
Search ERCC8 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

ERCC8_HUMAN
  • Cockayne syndrome A (CSA) [MIM:216400]: A rare disorder characterized by cutaneous sensitivity to sunlight, abnormal and slow growth, cachectic dwarfism, progeroid appearance, progressive pigmentary retinopathy and sensorineural deafness. There is delayed neural development and severe progressive neurologic degeneration resulting in mental retardation. Two clinical forms are recognized: in the classical form or Cockayne syndrome type 1, the symptoms are progressive and typically become apparent within the first few years or life; the less common Cockayne syndrome type 2 is characterized by more severe symptoms that manifest prenatally. Cockayne syndrome shows some overlap with certain forms of xeroderma pigmentosum. Unlike xeroderma pigmentosum, patients with Cockayne syndrome do not manifest increased freckling and other pigmentation abnormalities in the skin and have no significant increase in skin cancer. {ECO:0000269 PubMed:14661080, ECO:0000269 PubMed:15744458, ECO:0000269 PubMed:19894250}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • UV-sensitive syndrome 2 (UVSS2) [MIM:614621]: An autosomal recessive disorder characterized by cutaneous photosensitivity and mild freckling in the absence of neurological abnormalities or skin tumors. {ECO:0000269 PubMed:19329487}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for ERCC8

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ERCC8: view

No data available for Genatlas for ERCC8 Gene

Publications for ERCC8 Gene

  1. Characterisation of novel mutations in Cockayne syndrome type A and xeroderma pigmentosum group C subjects. (PMID: 15744458) Ridley AJ … Jones CJ (Journal of human genetics 2005) 3 4 22 58
  2. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. (PMID: 7664335) Henning KA … Friedberg EC (Cell 1995) 3 4 22 58
  3. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. (PMID: 22466612) Zhang X … Tanaka K (Nature genetics 2012) 3 4 58
  4. Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. (PMID: 20496165) Monsees GM … Han J (Breast cancer research and treatment 2011) 3 44 58
  5. Variation within DNA repair pathway genes and risk of multiple sclerosis. (PMID: 20522537) Briggs FB … International Multiple Sclerosis Genetics Consortium (American journal of epidemiology 2010) 3 44 58

Products for ERCC8 Gene

Sources for ERCC8 Gene

Content
Loading form....