Aliases for EPS8L1 Gene
External Ids for EPS8L1 Gene
Previous GeneCards Identifiers for EPS8L1 Gene
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for EPS8L1 Gene
EPS8L1 (EPS8 Like 1) is a Protein Coding gene. Diseases associated with EPS8L1 include Fetal Akinesia Deformation Sequence 4 and Bartter Syndrome, Type 1, Antenatal. Gene Ontology (GO) annotations related to this gene include actin binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is EPS8.
UniProtKB/Swiss-Prot Summary for EPS8L1 Gene
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.