Aliases for EPN2 Gene
External Ids for EPN2 Gene
Previous GeneCards Identifiers for EPN2 Gene
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for EPN2 Gene
EPN2 (Epsin 2) is a Protein Coding gene. Among its related pathways are Endocytic Trafficking of EGFR and Clathrin-mediated endocytosis. Gene Ontology (GO) annotations related to this gene include lipid binding and phospholipid binding. An important paralog of this gene is EPN1.
UniProtKB/Swiss-Prot Summary for EPN2 Gene
Plays a role in the formation of clathrin-coated invaginations and endocytosis.