Aliases for EPB41L4B Gene
External Ids for EPB41L4B Gene
Previous GeneCards Identifiers for EPB41L4B Gene
GeneCards Summary for EPB41L4B Gene
EPB41L4B (Erythrocyte Membrane Protein Band 4.1 Like 4B) is a Protein Coding gene. Diseases associated with EPB41L4B include Suppression Of Tumorigenicity 12. Among its related pathways are Tight junction. Gene Ontology (GO) annotations related to this gene include structural constituent of cytoskeleton and cytoskeletal protein binding.
UniProtKB/Swiss-Prot for EPB41L4B Gene
Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927).