Aliases for ENTPD8 Gene
External Ids for ENTPD8 Gene
Previous GeneCards Identifiers for ENTPD8 Gene
GeneCards Summary for ENTPD8 Gene
ENTPD8 (Ectonucleoside Triphosphate Diphosphohydrolase 8) is a Protein Coding gene. Among its related pathways are Pyrimidine metabolism (KEGG) and Purine metabolism. Gene Ontology (GO) annotations related to this gene include hydrolase activity and nucleoside-diphosphatase activity. An important paralog of this gene is ENTPD2.
UniProtKB/Swiss-Prot for ENTPD8 Gene
Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP.