Aliases for ENSG00000284762 Gene

Aliases for ENSG00000284762 Gene

  • Phosphodiesterase 8B 5
  • Phosphodiesterase 13
  • AC022414.1 5
  • EC 3.1.4.- 4

External Ids for ENSG00000284762 Gene

Summaries for ENSG00000284762 Gene

GeneCards Summary for ENSG00000284762 Gene

ENSG00000284762 is a Protein Coding gene. An important paralog of this gene is PDE8B.

Additional gene information for ENSG00000284762 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000284762 Gene

Genomics for ENSG00000284762 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000284762 Gene

Promoters and enhancers for ENSG00000284762 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J077085 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +0.6 556 4.2 EP300 MYC POLR2G USF1 JUND PHF8 ZFX ZNF639 CTCF ZBTB10 ZBED3-AS1 ENSG00000284762 ZBED3 lnc-WDR41-3 lnc-ZBED3-1 RF00017-4735 ENSG00000285000
GH05J077133 Enhancer 0.9 Ensembl ENCODE 0.3 +46.7 46668 1.6 TCF12 JUND FOS OSR2 FOXA2 ZNF184 FOSL2 CEBPB JUN EZH2 RF00017-4735 RF00017-4739 ENSG00000284762 ZBED3-AS1 ENSG00000285000
GH05J077091 Enhancer 0.3 Ensembl 0.7 +4.1 4068 0.4 ZNF10 ATF2 ENSG00000284762 ZBED3 ZBED3-AS1 lnc-ZBED3-1 RF00017-4735 ENSG00000285000
GH05J077139 Promoter/Enhancer 0.9 EPDnew Ensembl 0.2 +52.8 52769 1.4 ZIC2 ELF1 RXRA GLIS1 JUNB HNF4A NR3C1 ZNF558 FOXA1 SP7 PDE8B ZBED3-AS1 RF00017-4735 HMGB1P35 ENSG00000284762 ENSG00000285000
GH05J077166 Enhancer 1.1 Ensembl ENCODE 0.2 +81.4 81447 3.3 ZNF217 ZSCAN5C TCF12 ZNF300 ZNF623 ZNF510 RFX1 CUX1 KLF4 KLF7 ALDH7A1P1 TBCA RPL7P23 PDE8B RF00017-4740 ENSG00000284762 ZBED3-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000284762 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000284762 Gene

Genomic Locations for ENSG00000284762 Gene
chr5:77,086,732-77,427,124
(GRCh38/hg38)
Size:
340,393 bases
Orientation:
Plus strand

Genomic View for ENSG00000284762 Gene

Genes around ENSG00000284762 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000284762 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000284762 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000284762 Gene

Proteins for ENSG00000284762 Gene

  • Protein details for ENSG00000284762 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A2R8Y4E6-A0A2R8Y4E6_HUMAN
    Recommended name:
    Phosphodiesterase
    Protein Accession:
    A0A2R8Y4E6

    Protein attributes for ENSG00000284762 Gene

    Size:
    761 amino acids
    Molecular mass:
    86350 Da
    Cofactor:
    Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000284762 Gene

Post-translational modifications for ENSG00000284762 Gene

No Post-translational modifications

Other Protein References for ENSG00000284762 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000284762 Gene

Domains & Families for ENSG00000284762 Gene

Gene Families for ENSG00000284762 Gene

Unknown:
  • Belongs to the cyclic nucleotide phosphodiesterase family.
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ENSG00000284762 Gene

genes like me logo Genes that share domains with ENSG00000284762: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000284762 Gene

Function for ENSG00000284762 Gene

Enzyme Numbers (IUBMB) for ENSG00000284762 Gene

Phenotypes From GWAS Catalog for ENSG00000284762 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000284762 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008081 phosphoric diester hydrolase activity IEA --
GO:0016787 hydrolase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ENSG00000284762: view

No data available for Molecular function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000284762 Gene

Localization for ENSG00000284762 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ENSG00000284762 Gene

Pathways & Interactions for ENSG00000284762 Gene

PathCards logo

SuperPathways for ENSG00000284762 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for ENSG00000284762 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
genes like me logo Genes that share ontologies with ENSG00000284762: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ENSG00000284762 Gene

Drugs & Compounds for ENSG00000284762 Gene

(1) Drugs for ENSG00000284762 Gene - From: DGIdb

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
NM-702 Investigational Pharma inhibitor 0
genes like me logo Genes that share compounds with ENSG00000284762: view

Transcripts for ENSG00000284762 Gene

mRNA/cDNA for ENSG00000284762 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000284762 Gene

No ASD Table

Relevant External Links for ENSG00000284762 Gene

GeneLoc Exon Structure for
ENSG00000284762

Expression for ENSG00000284762 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000284762 Gene

Orthologs for ENSG00000284762 Gene

Evolution for ENSG00000284762 Gene

ENSEMBL:
Gene Tree for ENSG00000284762 (if available)
TreeFam:
Gene Tree for ENSG00000284762 (if available)

No data available for Orthologs for ENSG00000284762 Gene

Paralogs for ENSG00000284762 Gene

genes like me logo Genes that share paralogs with ENSG00000284762: view

Variants for ENSG00000284762 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000284762 Gene

Disorders for ENSG00000284762 Gene

No disorders were found for ENSG00000284762 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000284762 Gene

Publications for ENSG00000284762 Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J … Rubin EM (Nature 2004) 13 54
  2. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 13 54

No data available for Mastermind for ENSG00000284762 Gene

Products for ENSG00000284762 Gene

Sources for ENSG00000284762 Gene