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Aliases for ENSG00000278569 Gene

Subcategory (RNA class) for ENSG00000278569 Gene

SRP

Quality Score for this RNA gene is

14

Aliases for ENSG00000278569 Gene

  • RF00017 5

External Ids for ENSG00000278569 Gene

ORGUL Members for ENSG00000278569 Gene

Summaries for ENSG00000278569 Gene

GeneCards Summary for ENSG00000278569 Gene

ENSG00000278569 is an RNA Gene, and is affiliated with the SRP RNA class.

fRNAdb sequence ontologies for ENSG00000278569 Gene

  • Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.

View fRNAdb secondary structures for ENSG00000278569

Additional gene information for ENSG00000278569 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for ENSG00000278569 Gene

Genomics for ENSG00000278569 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000278569 Gene

Promoters and enhancers for ENSG00000278569 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J017205 Enhancer 1.2 Ensembl ENCODE 650.7 +1.1 1149 2.2 PKNOX1 ATF1 FOXA2 MLX ARID4B DMAP1 SLC30A9 TCF12 GATA2 ATF7 ENSG00000278569 LOC101927609 AHR ENSG00000283321
GH07J017185 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 -19.8 -19752 1 PKNOX1 BACH1 MAX BMI1 BATF IRF4 RAD21 EED ATF7 BCLAF1 AHR LOC101927609 ENSG00000278569 GC07P017080
GH07J017233 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.2 29236 3.5 SMAD1 IRF4 TCF12 ATF7 FOS RUNX3 JUNB ZC3H11A ZNF518A MEF2D AHR LOC101927609 SNX13 ENSG00000199473 ENSG00000236318 ENSG00000278569 ENSG00000283321
GH07J017129 Enhancer 1.5 FANTOM5 Ensembl ENCODE 0.2 -74.9 -74904 1.5 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 FOS AHR GC07P017080 ENSG00000278569 LOC101927609
GH07J017142 Enhancer 1.4 FANTOM5 Ensembl ENCODE 0.2 -62.2 -62176 2.6 ELF3 FOXA2 ARID4B THRB RARA ETS1 YY1 RCOR1 ATF7 FOS AHR LOC101927609 ENSG00000199473 ENSG00000236318 ENSG00000278569 GC07P017080
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ENSG00000278569 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000278569 Gene

Genomic Locations for ENSG00000278569 Gene
chr7:17,205,652-17,205,928
(GRCh38/hg38)
Size:
277 bases
Orientation:
Plus strand

Genomic View for ENSG00000278569 Gene

Genes around ENSG00000278569 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000278569 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000278569 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for ENSG00000278569 Gene

ORGUL Member Location for ENSG00000278569 gene

No data available for RefSeq DNA sequence for ENSG00000278569 Gene

Proteins for ENSG00000278569 Gene

Post-translational modifications for ENSG00000278569 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ENSG00000278569 Gene

Domains & Families for ENSG00000278569 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000278569 Gene

Function for ENSG00000278569 Gene

Phenotypes From GWAS Catalog for ENSG00000278569 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000278569 Gene

Localization for ENSG00000278569 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ENSG00000278569 Gene

Pathways & Interactions for ENSG00000278569 Gene

SuperPathways for ENSG00000278569 Gene

No Data Available

Interacting Proteins for ENSG00000278569 Gene

Gene Ontology (GO) - Biological Process for ENSG00000278569 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000278569 Gene

Drugs & Compounds for ENSG00000278569 Gene

No Compound Related Data Available

Transcripts for ENSG00000278569 Gene

fRNAdb Secondary structures for ENSG00000278569 Gene

  • FR000235

mRNA/cDNA for ENSG00000278569 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000278569 Gene

No ASD Table

Relevant External Links for ENSG00000278569 Gene

GeneLoc Exon Structure for
ENSG00000278569

Expression for ENSG00000278569 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000278569 Gene

Orthologs for ENSG00000278569 Gene

Evolution for ENSG00000278569 Gene

ENSEMBL:
Gene Tree for ENSG00000278569 (if available)
TreeFam:
Gene Tree for ENSG00000278569 (if available)

No data available for Orthologs for ENSG00000278569 Gene

Paralogs for ENSG00000278569 Gene

No data available for Paralogs for ENSG00000278569 Gene

Variants for ENSG00000278569 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000278569 Gene

Disorders for ENSG00000278569 Gene

No disorders were found for ENSG00000278569 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000278569 Gene

Publications for ENSG00000278569 Gene

  1. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C … Chen R (Nucleic acids research 2005) 1
  2. Structure, function and evolution of the signal recognition particle. (PMID: 12853463) Nagai K … Jovine L (The EMBO journal 2003) 1
  3. Structure of the phylogenetically most conserved domain of SRP RNA. (PMID: 10580470) Schmitz U … James TL (RNA (New York, N.Y.) 1999) 1
  4. The signal recognition particle (SRP) database. (PMID: 1317959) Zwieb C … Larsen N (Nucleic acids research 1992) 1

Products for ENSG00000278569 Gene

Sources for ENSG00000278569 Gene

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