Aliases for ENSG00000271810 Gene

Aliases for ENSG00000271810 Gene

  • PPM-Type Phosphatase Domain-Containing Protein 13
  • Novel Protein, PPM1J-RHOC Readthrough 5
  • Uncharacterized Protein 13
  • AL603832.3 5

External Ids for ENSG00000271810 Gene

Previous GeneCards Identifiers for ENSG00000271810 Gene

  • GC01M113249
  • GC01M113253

Summaries for ENSG00000271810 Gene

GeneCards Summary for ENSG00000271810 Gene

ENSG00000271810 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include GTP binding. An important paralog of this gene is RHOA.

Additional gene information for ENSG00000271810 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000271810 Gene

Genomics for ENSG00000271810 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ENSG00000271810 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J112713 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -4.0 -3967 3.6 BRCA1 GATAD2A CTCF HNRNPL TEAD4 PRDM10 RFX1 IKZF1 ZNF7 JUND PPM1J ENSG00000261595 LOC105378910 lnc-RHOC-2 MOV10 CTTNBP2NL ST7L ENSG00000271810
GH01J112696 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +9.0 8980 11.2 BRCA1 ARHGAP35 SP1 HNRNPL GATAD2A CTCF ATF7 PRDM10 ZNF629 TFE3 RHOC piR-31288 piR-45215 LRIG2 ST7L ENSG00000232499 DDX20 SLC16A1-AS1 WNT2B CAPZA1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000271810 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ENSG00000271810 Gene

Genomic Locations for ENSG00000271810 Gene
chr1:112,702,614-112,711,433
(GRCh38/hg38)
Size:
8,820 bases
Orientation:
Minus strand
chr1:113,245,236-113,254,055
(GRCh37/hg19)
Size:
8,820 bases
Orientation:
Minus strand

Genomic View for ENSG00000271810 Gene

Genes around ENSG00000271810 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000271810 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000271810 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000271810 Gene

Proteins for ENSG00000271810 Gene

  • Protein details for ENSG00000271810 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    U3KQA9-U3KQA9_HUMAN
    Recommended name:
    PPM-type phosphatase domain-containing protein
    Protein Accession:
    U3KQA9

    Protein attributes for ENSG00000271810 Gene

    Size:
    248 amino acids
    Molecular mass:
    28056 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000271810 Gene

Protein Expression for ENSG00000271810 Gene

Post-translational modifications for ENSG00000271810 Gene

No Post-translational modifications

Other Protein References for ENSG00000271810 Gene

No data available for DME Specific Peptides for ENSG00000271810 Gene

Domains & Families for ENSG00000271810 Gene

Gene Families for ENSG00000271810 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ENSG00000271810 Gene

genes like me logo Genes that share domains with ENSG00000271810: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000271810 Gene

Function for ENSG00000271810 Gene

Phenotypes From GWAS Catalog for ENSG00000271810 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000271810 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003824 catalytic activity IEA --
GO:0003924 GTPase activity IEA --
GO:0005525 GTP binding IEA --
GO:0019901 protein kinase binding IBA --
genes like me logo Genes that share ontologies with ENSG00000271810: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000271810 Gene

Localization for ENSG00000271810 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000271810 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
GO:0005938 cell cortex IBA --
GO:0031410 cytoplasmic vesicle IBA --
GO:0032153 cell division site IBA --
GO:0043005 neuron projection IBA --
genes like me logo Genes that share ontologies with ENSG00000271810: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000271810 Gene

Pathways & Interactions for ENSG00000271810 Gene

PathCards logo

SuperPathways for ENSG00000271810 Gene

No Data Available

Interacting Proteins for ENSG00000271810 Gene

Gene Ontology (GO) - Biological Process for ENSG00000271810 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007015 actin filament organization IBA --
GO:0007163 establishment or maintenance of cell polarity IBA --
GO:0007264 small GTPase mediated signal transduction IEA --
GO:0007266 Rho protein signal transduction IBA --
GO:0008360 regulation of cell shape IBA --
genes like me logo Genes that share ontologies with ENSG00000271810: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000271810 Gene

Drugs & Compounds for ENSG00000271810 Gene

No Compound Related Data Available

Transcripts for ENSG00000271810 Gene

mRNA/cDNA for ENSG00000271810 Gene

5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000271810 Gene

No ASD Table

Relevant External Links for ENSG00000271810 Gene

GeneLoc Exon Structure for
ENSG00000271810

Expression for ENSG00000271810 Gene

Protein differential expression in normal tissues from HIPED for ENSG00000271810 Gene

This gene is overexpressed in Testis (32.7) and Fetal ovary (16.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for ENSG00000271810 Gene



No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000271810 Gene

Orthologs for ENSG00000271810 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000271810 Gene

Organism Taxonomy Gene Similarity Type Details
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 55 (a)
ManyToMany
Mouse
(Mus musculus)
Mammalia Rhoa 31
  • 55 (a)
ManyToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 48 (a)
ManyToMany
Chicken
(Gallus gallus)
Aves CRHOA 31
  • 55 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 55 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii rhoab 31
  • 54 (a)
OneToMany
Fruit Fly
(Drosophila melanogaster)
Insecta Rho1 31
  • 54 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea rho-1 31
  • 54 (a)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RHO1 31
  • 42 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.11308 31
  • 53 (a)
OneToMany
Species where no ortholog for ENSG00000271810 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for ENSG00000271810 Gene

ENSEMBL:
Gene Tree for ENSG00000271810 (if available)
TreeFam:
Gene Tree for ENSG00000271810 (if available)

Paralogs for ENSG00000271810 Gene

genes like me logo Genes that share paralogs with ENSG00000271810: view

Variants for ENSG00000271810 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000271810 Gene

Disorders for ENSG00000271810 Gene

Additional Disease Information for ENSG00000271810

No disorders were found for ENSG00000271810 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ENSG00000271810 Gene

Publications for ENSG00000271810 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 13

No data available for Mastermind for ENSG00000271810 Gene

Products for ENSG00000271810 Gene

Sources for ENSG00000271810 Gene