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Aliases for ENSG00000268861 Gene

Aliases for ENSG00000268861 Gene

  • AC008878.3 5

External Ids for ENSG00000268861 Gene

Previous GeneCards Identifiers for ENSG00000268861 Gene

  • GC19P007446

Summaries for ENSG00000268861 Gene

GeneCards Summary for ENSG00000268861 Gene

ENSG00000268861 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF18.

Additional gene information for ENSG00000268861 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000268861 Gene

Genomics for ENSG00000268861 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000268861 Gene

Promoters and enhancers for ENSG00000268861 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I007380 Enhancer 1 FANTOM5 ENCODE 0.8 -2.0 -2029 0.3 ARID4B ZNF2 RAD21 ZNF335 ZNF121 ZNF143 ZNF654 ZNF280D ZNF362 PHF21A ARHGEF18 C3 ZNF557 STXBP2 PNPLA6 XAB2 EVI5L ENSG00000268861 GC19P007378 ENSG00000263264
GH19I007394 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.4 +12.7 12732 2.8 PKNOX1 ARID4B SIN3A ZNF48 ETS1 ZNF121 POLR2B GLIS2 E2F8 ELK1 ENSG00000267852 ARHGEF18 TEX45 PEX11G NDUFA7 ENSG00000268861 GC19P007434
GH19I007386 Enhancer 0.8 ENCODE 0.8 +4.4 4435 2 HDGF PKNOX1 ARID4B SIN3A BATF KLF5 IRF4 RAD21 EGR1 ZNF207 ENSG00000268861 ENSG00000267852 GC19P007378 ARHGEF18
GH19I007390 Enhancer 1.3 FANTOM5 Ensembl ENCODE 0.4 +8.8 8759 2 FOXA2 ARID4B SIN3A ATF7 FOS KLF13 TSHZ1 ZNF518A KAT8 NFIL3 ZNF557 XAB2 ELAVL1 GPR108 MAP2K7 KHSRP LRRC8E ARHGEF18 ENSG00000267852 ENSG00000268861
GH19I007415 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 0.3 +33.0 32956 1.4 ELF3 CLOCK FOXA2 MLX ARID4B DMAP1 ZNF48 ZSCAN9 RARA SLC30A9 ARHGEF18 GC19P007434 ENSG00000267852 ENSG00000268861
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ENSG00000268861 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000268861 Gene

Genomic Locations for ENSG00000268861 Gene
chr19:7,382,834-7,472,477
(GRCh38/hg38)
Size:
89,644 bases
Orientation:
Plus strand
chr19:7,445,850-7,535,131
(GRCh37/hg19)

Genomic View for ENSG00000268861 Gene

Genes around ENSG00000268861 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000268861 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000268861 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000268861 Gene

Proteins for ENSG00000268861 Gene

  • Protein details for ENSG00000268861 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WZG4
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    A0A087WZG4

    Protein attributes for ENSG00000268861 Gene

    Size:
    1122 amino acids
    Molecular mass:
    126215 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000268861 Gene

Post-translational modifications for ENSG00000268861 Gene

No Post-translational modifications

Other Protein References for ENSG00000268861 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000268861 Gene

Domains & Families for ENSG00000268861 Gene

Protein Domains for ENSG00000268861 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000268861: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000268861 Gene

Function for ENSG00000268861 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000268861 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA --
genes like me logo Genes that share ontologies with ENSG00000268861: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000268861 Gene

Localization for ENSG00000268861 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ENSG00000268861 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with ENSG00000268861: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ENSG00000268861 Gene

Pathways & Interactions for ENSG00000268861 Gene

SuperPathways for ENSG00000268861 Gene

No Data Available

Interacting Proteins for ENSG00000268861 Gene

Gene Ontology (GO) - Biological Process for ENSG00000268861 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035023 regulation of Rho protein signal transduction IEA --
GO:0065009 regulation of molecular function IEA --
genes like me logo Genes that share ontologies with ENSG00000268861: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000268861 Gene

Drugs & Compounds for ENSG00000268861 Gene

No Compound Related Data Available

Transcripts for ENSG00000268861 Gene

mRNA/cDNA for ENSG00000268861 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000268861 Gene

No ASD Table

Relevant External Links for ENSG00000268861 Gene

GeneLoc Exon Structure for
ENSG00000268861

Expression for ENSG00000268861 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000268861 Gene

Orthologs for ENSG00000268861 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENSG00000268861 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 88 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Arhgef18 34
  • 80 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 74 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 70 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 70 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 69 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 57 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii arhgef18b 34
  • 47 (a)
ManyToMany
arhgef18a 34
  • 40 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG10188 34
  • 19 (a)
OneToMany
Species where no ortholog for ENSG00000268861 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ENSG00000268861 Gene

ENSEMBL:
Gene Tree for ENSG00000268861 (if available)
TreeFam:
Gene Tree for ENSG00000268861 (if available)

Paralogs for ENSG00000268861 Gene

Paralogs for ENSG00000268861 Gene

genes like me logo Genes that share paralogs with ENSG00000268861: view

Variants for ENSG00000268861 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000268861 Gene

Disorders for ENSG00000268861 Gene

No disorders were found for ENSG00000268861 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000268861 Gene

Publications for ENSG00000268861 Gene

No publications were found for ENSG00000268861 Gene.

Products for ENSG00000268861 Gene

Sources for ENSG00000268861 Gene

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