Aliases for ENSG00000268465 Gene
External Ids for ENSG00000268465 Gene
- Ensembl: ENSG00000268465
- UniProtKB: M0QZ92
Previous GeneCards Identifiers for ENSG00000268465 Gene
- GC19P048969
Summaries for ENSG00000268465 Gene
GeneCards Summary for ENSG00000268465 Gene
ENSG00000268465 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is CYTH2.
Additional gene information for ENSG00000268465 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000268465 Gene
Genomics for ENSG00000268465 Gene
GeneHancer (GH) Regulatory Elements for ENSG00000268465 Gene
Promoters and enhancers for ENSG00000268465 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH19J048468 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE dbSUPER | 0.7 | +3.8 | 3773 | 3 | SP1 ZFX MNT NKRF POLR2A MLLT1 GTF2F1 CSDE1 ZNF687 FOS | CYTH2 ENSG00000268530 LOC105372430 GRWD1 SNRNP70 NOP53-AS1 BICRA ALDH16A1 PIH1D1 NOP53 | |
| GH19J048462 | Enhancer | 0.7 | ENCODE | 0.7 | -3.3 | -3338 | 0.2 | SIX5 EGR1 ZNF143 DEAF1 NR2C1 POLR2A NR2C2 HCFC1 IRF2 SUPT5H | SYNGR4 TMEM143 LMTK3 ENSG00000268465 KCNJ14 | |
| GH19J048455 | Promoter | 0.5 | EPDnew | 0.4 | -10.3 | -10277 | 0.1 | KCNJ14 GRWD1 ENSG00000268465 | ||
| GH19J048471 | Enhancer | 0.2 | FANTOM5 | 0.4 | +5.8 | 5826 | 0.1 | ENSG00000268530 CYTH2 ENSG00000268465 GC19P048479 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ENSG00000268465 on UCSC Golden Path with GeneCards custom track
Genomic Locations for ENSG00000268465 Gene
Genomic Locations for ENSG00000268465 Gene
- chr19:48,465,837-48,472,431
- (GRCh38/hg38)
- Size:
- 6,595 bases
- Orientation:
- Plus strand
- chr19:48,969,094-48,975,688
- (GRCh37/hg19)
- Size:
- 6,595 bases
- Orientation:
- Plus strand
Genomic View for ENSG00000268465 Gene
Genes around ENSG00000268465 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
ENSG00000268465 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
No data available for RefSeq DNA sequence for ENSG00000268465 Gene
Proteins for ENSG00000268465 Gene
-
Protein details for ENSG00000268465 Gene (UniProtKB/TrEMBL)
- Protein Symbol:
- M0QZ92-M0QZ92_HUMAN
- Recommended name:
- Uncharacterized protein
- Protein Accession:
- M0QZ92
Protein attributes for ENSG00000268465 Gene
- Size:
- 97 amino acids
- Molecular mass:
- 11308 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for ENSG00000268465 Gene
No Post-translational modifications
Other Protein References for ENSG00000268465 Gene
- ENSEMBL proteins:
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ENSG00000268465
- Origene Custom Protein Services for ENSG00000268465
No data available for DME Specific Peptides for ENSG00000268465 Gene
Domains & Families for ENSG00000268465 Gene
Protein Domains for ENSG00000268465 Gene
- InterPro:
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000268465 Gene
Function for ENSG00000268465 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ENSG00000268465
-
miRNA Products
Inhibitory RNA Products
Clone Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000268465 Gene
Localization for ENSG00000268465 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ENSG00000268465 Gene
Pathways & Interactions for ENSG00000268465 Gene
Interacting Proteins for ENSG00000268465 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0032012 | regulation of ARF protein signal transduction | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ENSG00000268465 Gene
Transcripts for ENSG00000268465 Gene
mRNA/cDNA for ENSG00000268465 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000595676 443 bps (ENST00000595676.1)
CRISPR Products
- Browse CRISPR knockouts for ENSG00000268465
miRNA Products
Inhibitory RNA Products
Clone Products
Relevant External Links for ENSG00000268465 Gene
- GeneLoc Exon Structure for
- ENSG00000268465
Expression for ENSG00000268465 Gene
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000268465 Gene
Orthologs for ENSG00000268465 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | CYTH2 35 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | CYTH2 35 |
|
OneToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | step 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | grp-1 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SEC7 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8851 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany |
- Species where no ortholog for ENSG00000268465 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for ENSG00000268465 Gene
Variants for ENSG00000268465 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000268465 Gene
Disorders for ENSG00000268465 Gene
No disorders were found for ENSG00000268465 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000268465 Gene
Publications for ENSG00000268465 Gene
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 13 58
No data available for External Links for ENSG00000268465 Gene
Products for ENSG00000268465 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ENSG00000268465
- Origene Custom Protein Services for ENSG00000268465
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- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for ENSG00000268465
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ENSG00000268465
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Cyagen custom Knockout/knockin (KOKI) mouse models for ENSG00000268465
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for ENSG00000268465
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for ENSG00000268465
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ENSG00000268465
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for ENSG00000268465
Sources for ENSG00000268465 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) HGMD
- (45) GAD
- (46) BGMUT
- (47) HuGE
- (48) Atlas
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) OCA
- (69) Proteopedia
- (70) MOPED
- (71) neXtProt
- (72) Reactome
- (73) GeneGo (Thomson Reuters)
- (74) fRNAdb
- (75) DISEASES
- (76) SIMAP
- (77) GenomeRNAi
- (78) LifeMap
- (79) miRTarBase
- (80) MalaCards
- (81) Invitrogen
- (82) BitterDB
- (83) ESI-BIO
- (84) RefSeq
- (85) BioSystems
- (86) MaxQB
- (87) IUPHAR
- (88) BioGPS
- (89) Illumina
- (90) COMPARTMENTS
- (91) HOMER
- (92) PaxDb
- (93) ApexBio
- (94) Addgene
- (95) antibodies-online
- (96) CYP
- (97) NONCODE
- (98) SwitchGear Genomics
- (99) TreeFam
- (100) PathCards
- (101) GeneReviews
- (102) GeneTex
- (103) Taconic Biosciences
- (104) GTEx
- (105) ProteomicsDB
- (106) SCBT
- (107) DGIdb
- (108) ClinicalTrials
- (109) FDA Approved Drugs
- (110) RVIS
- (111) SIGNOR
- (112) diseasecard
- (113) NIH Rare Diseases
- (114) Orphanet
- (115) UMLS
- (116) GTR
- (117) Disease Ontology
- (118) Genetics Home Reference
- (119) MeSH
- (120) MedlinePlus
- (121) CDC
- (122) NINDS
- (123) NCBI Bookshelf
- (124) ClinVar
- (125) Gene Damage Index
- (126) ViGene Biosciences
- (127) HPO
- (128) UDN
- (129) VISTA
- (130) FANTOM5
- (131) ENCODE
- (132) ProSci
- (133) Horizon
- (134) NURSA
- (135) IID
- (136) Cyagen
- (137) VectorBuilder
- (138) SNPedia
- (139) BRCA Exchange
- (140) St John's Lab
- (141) CIViC
- (142) ProteoGenix
- (143) dbSUPER
- (144) TISSUES
- (145) Gene ORGANizer
- (146) abm
- (147) CrownBio
- (148) Human Protein Atlas
- (149) GWAS Catalog
- (150) Monarch Initiative
- (151) DataMed
- (152) HumanCyc
- (153) genomics-online
- (154) UCNEbase
- (155) EPDnew
- (156) Applied Biosystems
- (157) GlyConnect
- (158) Aminode
- (159) GeneCopoeia
- (160) GPS-Prot
- (161) RNACentral
- (162) LncRNADisease
- (163) LOVD
- (164) miR2Disease
- (165) DiseaseEnhancer
- (166) Boster Bio
- (167) Biorbyt
- (168) Biocompare
- (169) Mastermind