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Aliases for ENSG00000260643 Gene

Aliases for ENSG00000260643 Gene

  • AC092718.3 5

External Ids for ENSG00000260643 Gene

Previous GeneCards Identifiers for ENSG00000260643 Gene

  • GC16M081088

Summaries for ENSG00000260643 Gene

GeneCards Summary for ENSG00000260643 Gene

ENSG00000260643 is a Protein Coding gene. An important paralog of this gene is GCSH.

Additional gene information for ENSG00000260643 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000260643 Gene

Genomics for ENSG00000260643 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000260643 Gene

Promoters and enhancers for ENSG00000260643 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J081094 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 0.0 -11 2.7 HDGF PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A YY1 ZNF766 ZNF207 GCSH ENSG00000260643 ENSG00000284512 ATMIN PKD1L2
GH16J081076 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.4 +19.1 19133 2.1 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 SLC30A9 C16orf46 ENSG00000245059 ATMIN LOC105371361 ENSG00000260643 ENSG00000284512
GH16J081090 Promoter 0.5 EPDnew 0.4 +5.6 5598 0.1 GCSH ATMIN ENSG00000260643 ENSG00000284512 ENSG00000245059
GH16J081087 Promoter 0.5 EPDnew 0.4 +8.6 8623 0.1 GCSH ENSG00000284512 ENSG00000260643 ENSG00000245059
GH16J081082 Promoter 0.5 EPDnew 0.4 +13.9 13925 0.1 GCSH RNU6-1191P ENSG00000245059 ENSG00000260643 ENSG00000284512
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ENSG00000260643 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000260643 Gene

Genomic Locations for ENSG00000260643 Gene
chr16:81,053,587-81,096,296
(GRCh38/hg38)
Size:
42,710 bases
Orientation:
Minus strand
chr16:81,087,270-81,121,256
(GRCh37/hg19)
Size:
33,987 bases
Orientation:
Minus strand

Genomic View for ENSG00000260643 Gene

Genes around ENSG00000260643 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000260643 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000260643 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000260643 Gene

Proteins for ENSG00000260643 Gene

  • Protein details for ENSG00000260643 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A1W2PPQ1-A0A1W2PPQ1_HUMAN
    Recommended name:
    Glycine cleavage system H protein
    Protein Accession:
    A0A1W2PPQ1

    Protein attributes for ENSG00000260643 Gene

    Size:
    181 amino acids
    Molecular mass:
    19629 Da
    Cofactor:
    Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
    Quaternary structure:
    • The glycine cleavage system is composed of four proteins: P, T, L and H.

neXtProt entry for ENSG00000260643 Gene

Post-translational modifications for ENSG00000260643 Gene

No Post-translational modifications

Other Protein References for ENSG00000260643 Gene

No data available for DME Specific Peptides for ENSG00000260643 Gene

Domains & Families for ENSG00000260643 Gene

Gene Families for ENSG00000260643 Gene

Unknown:
  • Belongs to the GcvH family.
  • Belongs to the GcvH family.
  • Belongs to the GcvH family.

Protein Domains for ENSG00000260643 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000260643: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000260643 Gene

Function for ENSG00000260643 Gene

Molecular function for ENSG00000260643 Gene

UniProtKB/TrEMBL Function:
The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  • A0A1W2PRH4
  • A0A1W2PPQ1
  • A0A1W2PPE4

Phenotypes From GWAS Catalog for ENSG00000260643 Gene

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000260643 Gene

Localization for ENSG00000260643 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ENSG00000260643 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005960 glycine cleavage complex IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000260643: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ENSG00000260643 Gene

Pathways & Interactions for ENSG00000260643 Gene

SuperPathways for ENSG00000260643 Gene

No Data Available

Interacting Proteins for ENSG00000260643 Gene

Gene Ontology (GO) - Biological Process for ENSG00000260643 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019464 glycine decarboxylation via glycine cleavage system IEA --
genes like me logo Genes that share ontologies with ENSG00000260643: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000260643 Gene

Drugs & Compounds for ENSG00000260643 Gene

No Compound Related Data Available

Transcripts for ENSG00000260643 Gene

mRNA/cDNA for ENSG00000260643 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000260643 Gene

No ASD Table

Relevant External Links for ENSG00000260643 Gene

GeneLoc Exon Structure for
ENSG00000260643

Expression for ENSG00000260643 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ENSG00000260643 Gene

genes like me logo Genes that share expression patterns with ENSG00000260643: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000260643 Gene

Orthologs for ENSG00000260643 Gene

Evolution for ENSG00000260643 Gene

ENSEMBL:
Gene Tree for ENSG00000260643 (if available)
TreeFam:
Gene Tree for ENSG00000260643 (if available)

No data available for Orthologs for ENSG00000260643 Gene

Paralogs for ENSG00000260643 Gene

Paralogs for ENSG00000260643 Gene

genes like me logo Genes that share paralogs with ENSG00000260643: view

Variants for ENSG00000260643 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000260643 Gene

Disorders for ENSG00000260643 Gene

No disorders were found for ENSG00000260643 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000260643 Gene

Publications for ENSG00000260643 Gene

No publications were found for ENSG00000260643 Gene.

Products for ENSG00000260643 Gene

Sources for ENSG00000260643 Gene

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